Epigenetic dysregulation of hairy and enhancer of split 4 (HES4) is associated with striatal degeneration in postmortem Huntington brains

Phosphorylation of neuronal Lysine-Specific Demethylase 1LSD1/KDM1A impairs transcriptional repression by regulating interaction with CoREST and histone deacetylases HDAC1/2

(2013) Emanuela Toffolo et al.   JOURNAL OF NEUROCHEMISTRY

Making sense of genetic heterogeneity: Emergence of pathways in developmental brain disorders

(2013) A. R. Paciorkowski et al.   NEUROLOGY

Targeting H3K4 trimethylation in Huntington disease

(2013) M. Vashishtha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GPR179 Is Required for Depolarizing Bipolar Cell Function and Is Mutated in Autosomal-Recessive Complete Congenital Stationary Night Blindness

(2012) Neal S. Peachey et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Structure-Function of the G Protein–Coupled Receptor Superfamily

(2012) Vsevolod Katritch et al.   Annual Review of Pharmacology and Toxicology

Like a rolling histone: Epigenetic regulation of neural stem cells and brain development by factors controlling histone acetylation and methylation

(2012) Tobias Lilja et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Restructuring G-Protein- Coupled Receptor Activation

(2012) Martin Audet et al.   CELL

ATRX induction by mutant huntingtin via Cdx2 modulates heterochromatin condensation and pathology in Huntington's disease

(2012) J Lee et al.   CELL DEATH AND DIFFERENTIATION

Epigenetic mechanisms in neurological disease

(2012) Mira Jakovcevski et al.   NATURE MEDICINE

β-arrestin 2 regulates Aβ generation and γ-secretase activity in Alzheimer's disease

(2012) Amantha Thathiah et al.   NATURE MEDICINE

TMEM106B risk variant is implicated in the pathologic presentation of Alzheimer disease

(2012) N. J. Rutherford et al.   NEUROLOGY

Assessment of cortical and striatal involvement in 523 Huntington disease brains

(2012) T. C. Hadzi et al.   NEUROLOGY

Novel INF2 mutation p. L77P in a family with glomerulopathy and Charcot-Marie-Tooth neuropathy

(2012) Patricia Q. Rodriguez et al.   PEDIATRIC NEPHROLOGY

Hes4 Controls Proliferative Properties of Neural Stem Cells During Retinal Ontogenesis

(2012) Warif El Yakoubi et al.   STEM CELLS

Transcription Elongation and Tissue-Specific Somatic CAG Instability

(2012) Agathi-Vasiliki Goula et al.   PLoS Genetics

Epigenetic Signatures of Autism

(2011) Hennady P. Shulha   ARCHIVES OF GENERAL PSYCHIATRY

Functionally biased modulation of A3 adenosine receptor agonist efficacy and potency by imidazoquinolinamine allosteric enhancers

(2011) Zhan-Guo Gao et al.   BIOCHEMICAL PHARMACOLOGY

Jagged2 controls the generation of motor neuron and oligodendrocyte progenitors in the ventral spinal cord

(2011) M A Rabadán et al.   CELL DEATH AND DIFFERENTIATION

Brain networks in Huntington disease

(2011) David Eidelberg et al.   JOURNAL OF CLINICAL INVESTIGATION

Functional selectivity of adenosine receptor ligands

(2011) Dennis Verzijl et al.   Purinergic Signalling

ChIPpeakAnno: a Bioconductor package to annotate ChIP-seq and ChIP-chip data

(2010) Lihua J Zhu et al.   BMC BIOINFORMATICS

Conserved role of intragenic DNA methylation in regulating alternative promoters

(2010) Alika K. Maunakea et al.   NATURE

Teaching old receptors new tricks: biasing seven-transmembrane receptors

(2010) Sudarshan Rajagopal et al.   NATURE REVIEWS DRUG DISCOVERY

Charting histone modifications and the functional organization of mammalian genomes

(2010) Vicky W. Zhou et al.   NATURE REVIEWS GENETICS

TMEM106B is a susceptibility locus for FTLD

(2010) Heather B. Wood   Nature Reviews Neurology

TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers

(2010) N. Finch et al.   NEUROLOGY

Developmental regulation and individual differences of neuronal H3K4me3 epigenomes in the prefrontal cortex

(2010) I. Cheung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Huntingtin facilitates polycomb repressive complex 2

(2009) Ihn Sik Seong et al.   HUMAN MOLECULAR GENETICS

Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies

(2009) Rocio G Urdinguio et al.   LANCET NEUROLOGY

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

(2009) Mitchell Guttman et al.   NATURE

Huntington's disease: the case for genetic modifiers

(2009) James F Gusella et al.   Genome Medicine

Chromatin switching and transcriptional regulation in disease

(2008) Lezanne Ooi et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Epigenetic Regulation in Human Brain—Focus on Histone Lysine Methylation

(2008) Schahram Akbarian et al.   BIOLOGICAL PSYCHIATRY

Isolation of neuronal chromatin from brain tissue

(2008) Yan Jiang et al.   BMC NEUROSCIENCE

Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2

(2008) D. Pasini et al.   GENES & DEVELOPMENT

NGF-promoted axon growth and target innervation requires GITRL-GITR signaling

(2008) Gerard W O'Keeffe et al.   NATURE NEUROSCIENCE

The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice

(2008) E. A. Thomas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Novel CpG Island Set Identifies Tissue-Specific Methylation at Developmental Gene Loci

(2008) Robert Illingworth et al.   PLOS BIOLOGY