Association of polyalanine and polyglutamine coiled coils mediates expansion disease-related protein aggregation and dysfunction

Analysis of De NovoHOXA13Polyalanine Expansions Supports Replication Slippage Without Repair in Their Generation

(2013) Kailey M. Owens et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Coiled-coil motifs enhance the toxicity of polyQ proteins (Comment on DOI 10.1002/bies.201300001)

(2013) Wlodzimierz J. Krzyzosiak   BIOESSAYS

Depletion of Cognate Charged Transfer RNA Causes Translational Frameshifting within the Expanded CAG Stretch in Huntingtin

(2013) Hannah Girstmair et al.   Cell Reports

Trinucleotide Repeats: A Structural Perspective

(2013) Bruno Almeida et al.   Frontiers in Neurology

The Amyloid State of Proteins in Human Diseases

(2012) David Eisenberg et al.   CELL

Polyglutamine neurodegeneration: expanded glutamines enhance native functions

(2012) Harry T Orr   CURRENT OPINION IN GENETICS & DEVELOPMENT

DEF6, a Novel Substrate for the Tec Kinase ITK, Contains a Glutamine-rich Aggregation-prone Region and Forms Cytoplasmic Granules that Co-localize with P-bodies

(2012) Fiona Hey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polyalanine-independent Conformational Conversion of Nuclear Poly(A)-binding Protein 1 (PABPN1)

(2012) Reno Winter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assessing Polyglutamine Conformation in the Nucleating Event by Molecular Dynamics Simulations

(2012) Markus S. Miettinen et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Evolution and function of CAG/polyglutamine repeats in protein–protein interaction networks

(2012) Martin H. Schaefer et al.   NUCLEIC ACIDS RESEARCH

Glutamine Repeat Variants in Human RUNX2 Associated with Decreased Femoral Neck BMD, Broadband Ultrasound Attenuation and Target Gene Transactivation

(2012) Nigel A. Morrison et al.   PLoS One

Control of Nonapoptotic Developmental Cell Death in Caenorhabditis elegans by a Polyglutamine-Repeat Protein

(2012) E. S. Blum et al.   SCIENCE

PolyQ disease: misfiring of a developmental cell death program?

(2012) Elyse S. Blum et al.   TRENDS IN CELL BIOLOGY

Identification of Human Proteins That Modify Misfolding and Proteotoxicity of Pathogenic Ataxin-1

(2012) Spyros Petrakis et al.   PLoS Genetics

Length-Dependent Aggregation of Uninterrupted Polyalanine Peptides

(2011) Joseph P. Bernacki et al.   BIOCHEMISTRY

Molecular dynamics simulations of the folding of poly(alanine) peptides

(2011) Peter Palenčár et al.   JOURNAL OF MOLECULAR MODELING

Triplet repeat RNA structure and its role as pathogenic agent and therapeutic target

(2011) W. J. Krzyzosiak et al.   NUCLEIC ACIDS RESEARCH

Alanine Zipper-Like Coiled-Coil Domains Are Necessary for Homotypic Dimerization of Plant GAGA-Factors in the Nucleus and Nucleolus

(2011) Dierk Wanke et al.   PLoS One

Recent progress in understanding Alzheimer's β-amyloid structures

(2011) Marcus Fändrich et al.   TRENDS IN BIOCHEMICAL SCIENCES

Essential Role of Coiled Coils for Aggregation and Activity of Q/N-Rich Prions and PolyQ Proteins

(2010) Ferdinando Fiumara et al.   CELL

Natural selection drives the accumulation of amino acid tandem repeats in human proteins

(2010) L. Mularoni et al.   GENOME RESEARCH

Assessing mutant huntingtin fragment and polyglutamine aggregation by atomic force microscopy

(2010) Kathleen A. Burke et al.   METHODS

Elevated Evolutionary Rate in Genes with Homopolymeric Amino Acid Repeats Constituting Nondisordered Structure

(2010) J. Gojobori et al.   MOLECULAR BIOLOGY AND EVOLUTION

Repeat expansion disease: progress and puzzles in disease pathogenesis

(2010) Albert R. La Spada et al.   NATURE REVIEWS GENETICS

PolyQ Disease: Too Many Qs, Too Much Function?

(2010) Ian H. Kratter et al.   NEURON

Plasticity of Intermediate Filament Subunits

(2010) Robert Kirmse et al.   PLoS One

Protein destabilization by electrostatic repulsions in the two-stranded α-helical coiled-coil/leucine zipper

(2010) Wayne D. Kohn et al.   PROTEIN SCIENCE

Salt Dependence of an α-Helical Peptide Folding Energy Landscapes

(2009) Kan Xiong et al.   BIOCHEMISTRY

Identification of a Unique “Stability Control Region” that Controls Protein Stability of Tropomyosin: A Two-stranded α-Helical Coiled-coil

(2009) Robert S. Hodges et al.   JOURNAL OF MOLECULAR BIOLOGY

Repression of Runx2 by Androgen Receptor (AR) in Osteoblasts and Prostate Cancer Cells: AR Binds Runx2 and Abrogates Its Recruitment to DNA

(2009) Sanjeev K. Baniwal et al.   MOLECULAR ENDOCRINOLOGY

Molecular mechanisms underlying polyalanine diseases

(2009) C. Messaed et al.   NEUROBIOLOGY OF DISEASE

Hsp70 Chaperones and Type I PRMTs Are Sequestered at Intranuclear Inclusions Caused by Polyalanine Expansions in PABPN1

(2009) João Paulo Tavanez et al.   PLoS One

BioVenn – a web application for the comparison and visualization of biological lists using area-proportional Venn diagrams

(2008) Tim Hulsen et al.   BMC GENOMICS

Fifty years of coiled-coils and α-helical bundles: A close relationship between sequence and structure

(2008) David A.D. Parry et al.   JOURNAL OF STRUCTURAL BIOLOGY

Coiled-Coil Irregularities and Instabilities in Group A Streptococcus M1 Are Required for Virulence

(2008) C. McNamara et al.   SCIENCE