Absence of ALOX5 gene prevents stress-induced memory deficits, synaptic dysfunction and tauopathy in a mouse model of Alzheimer's disease

Knockout of 5-lipoxygenase prevents dexamethasone-induced tau pathology in 3xTg mice

(2013) Yash B. Joshi et al.   AGING CELL

5-Lipoxygenase Activating Protein Reduction Ameliorates Cognitive Deficit, Synaptic Dysfunction, and Neuropathology in a Mouse Model of Alzheimer’s Disease

(2013) Phillip F. Giannopoulos et al.   BIOLOGICAL PSYCHIATRY

Gene knockout of 5-lipoxygenase rescues synaptic dysfunction and improves memory in the triple-transgenic model of Alzheimer's disease

(2013) P F Giannopoulos et al.   MOLECULAR PSYCHIATRY

Modulation of lipopolysaccharide-induced memory insult, γ-secretase, and neuroinflammation in triple transgenic mice by 5-lipoxygenase

(2013) Yash B. Joshi et al.   NEUROBIOLOGY OF AGING

5-Lipoxygenase gene transfer worsens memory, amyloid, and tau brain pathologies in a mouse model of alzheimer disease

(2012) Jin Chu et al.   ANNALS OF NEUROLOGY

Early Presynaptic and Postsynaptic Calcium Signaling Abnormalities Mask Underlying Synaptic Depression in Presymptomatic Alzheimer's Disease Mice

(2012) S. Chakroborty et al.   JOURNAL OF NEUROSCIENCE

Longitudinal assessment of Aβ and cognition in aging and Alzheimer disease

(2011) Victor L. Villemagne et al.   ANNALS OF NEUROLOGY

Chronic Stress Exacerbates Tau Pathology, Neurodegeneration, and Cognitive Performance through a Corticotropin-Releasing Factor Receptor-Dependent Mechanism in a Transgenic Mouse Model of Tauopathy

(2011) J. C. Carroll et al.   JOURNAL OF NEUROSCIENCE

Knockout of 5-Lipoxygenase Results in Age-Dependent Anxiety-Like Behavior in Female Mice

(2011) Yash B. Joshi et al.   PLoS One

Elevated basal cortisol level predicts lower hippocampal volume and cognitive decline in Alzheimer’s disease

(2009) Chi-Wei Huang et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Caffeic acid attenuates the decrease of cortical BDNF transcript IV mRNA induced by swim stress in wild-type but not in 5-lipoxygenase-deficient mice

(2008) Svetlana Dzitoyeva et al.   JOURNAL OF NEURAL TRANSMISSION

Behavioral stress accelerates plaque pathogenesis in the brain of Tg2576 mice via generation of metabolic oxidative stress

(2008) Kang-Woo Lee et al.   JOURNAL OF NEUROCHEMISTRY