Genetic instability in lymphoblastoid cell lines expressing biallelic and monoallelic variants in the human MUTYH gene

Role of MUTYH in human cancer

(2013) Filomena Mazzei et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Understanding the role of the Q338H MUTYH variant in oxidative damage repair

(2013) Eleonora Turco et al.   NUCLEIC ACIDS RESEARCH

Base excision repair and cancer

(2012) Susan S. Wallace et al.   CANCER LETTERS

Loss of MUTYH function in human cells leads to accumulation of oxidative damage and genetic instability

(2012) V Ruggieri et al.   ONCOGENE

A large-scale meta-analysis to refine colorectal cancer risk estimates associated with MUTYH variants

(2010) E Theodoratou et al.   BRITISH JOURNAL OF CANCER

Functional analysis of MUTYH mutated proteins associated with familial adenomatous polyposis

(2010) Vito G. D’Agostino et al.   DNA REPAIR

Oxygen as a friend and enemy: How to combat the mutational potential of 8-oxo-guanine

(2010) Barbara van Loon et al.   DNA REPAIR

Association between monoallelic MUTYH mutation and colorectal cancer risk: a meta-regression analysis

(2010) Aung Ko Win et al.   Familial Cancer

Adenine DNA glycosylase activity of 14 Human MutY homolog (MUTYH) variant proteins found in patients with colorectal polyposis and cancer

(2010) Masanori Goto et al.   HUMAN MUTATION

Cancer risks for monoallelic MUTYH mutation carriers with a family history of colorectal cancer

(2010) Aung Ko Win et al.   INTERNATIONAL JOURNAL OF CANCER

A Structural Hinge in Eukaryotic MutY Homologues Mediates Catalytic Activity and Rad9–Rad1–Hus1 Checkpoint Complex Interactions

(2010) Paz J. Luncsford et al.   JOURNAL OF MOLECULAR BIOLOGY

Role of MUTYH and MSH2 in the Control of Oxidative DNA Damage, Genetic Instability, and Tumorigenesis

(2009) M. T. Russo et al.   CANCER RESEARCH

Adenine removal activity and bacterial complementation with the human MutY homologue (MUTYH) and Y165C, G382D, P391L and Q324R variants associated with colorectal cancer

(2009) Sucharita Kundu et al.   DNA REPAIR

Expanded Extracolonic Tumor Spectrum in MUTYH-Associated Polyposis

(2009) Stefanie Vogt et al.   GASTROENTEROLOGY

MUTYHmutations associated with familial adenomatous polyposis: functional characterization by a mammalian cell-based assay

(2009) Sara Molatore et al.   HUMAN MUTATION

Clinical Implications of the Colorectal Cancer Risk Associated With MUTYH Mutation

(2009) Steven J. Lubbe et al.   JOURNAL OF CLINICAL ONCOLOGY

The use of PIG-A as a sentinel gene for the study of the somatic mutation rate and of mutagenic agents in vivo

(2009) Benedetta Peruzzi et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Redox signaling between DNA repair proteins for efficient lesion detection

(2009) A. K. Boal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An 8-oxo-guanine repair pathway coordinated by MUTYH glycosylase and DNA polymerase  

(2009) B. van Loon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of Mutant MUTYH Proteins Associated With Familial Colorectal Cancer

(2008) Mohsin Ali et al.   GASTROENTEROLOGY

Analysis of MUTYH Genotypes and Colorectal Phenotypes in Patients With MUTYH-Associated Polyposis

(2008) Maartje Nielsen et al.   GASTROENTEROLOGY

Overexpression of human NOX1 complex induces genome instability in mammalian cells

(2007) Federica Chiera et al.   FREE RADICAL BIOLOGY AND MEDICINE