The IRF5–TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share

The genomic landscape of Neanderthal ancestry in present-day humans

(2014) Sriram Sankararaman et al.   NATURE

DNA-Binding Specificities of Human Transcription Factors

(2013) Arttu Jolma et al.   CELL

Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome

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Identification of three new cis-regulatory IRF5 polymorphisms: in vitro studies

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Genome-wide Association Study Identifies TNFSF15 and POU2AF1 as Susceptibility Loci for Primary Biliary Cirrhosis in the Japanese Population

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Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as Susceptibility Loci for Systemic Lupus Erythematosus in a Large-Scale Multiracial Replication Study

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Interferon Regulatory Factor 5 in the Pathogenesis of Systemic Lupus Erythematosus

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Irf5-deficient mice are protected from pristane-induced lupus via increased Th2 cytokines and altered IgG class switching

(2012) Di Feng et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Erratum: Interferon regulatory factor 5 gene variants and pharmacological and clinical outcome of Interferonb therapy in multiple sclerosis

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Immunochip analyses identify a novel risk locus for primary biliary cirrhosis at 13q14, multiple independent associations at four established risk loci and epistasis between 1p31 and 7q32 risk variants

(2012) Brian D. Juran et al.   HUMAN MOLECULAR GENETICS

Identification of CSK as a systemic sclerosis genetic risk factor through Genome Wide Association Study follow-up

(2012) Jose-Ezequiel Martin et al.   HUMAN MOLECULAR GENETICS

Interaction of the HIV-1 Intasome with Transportin 3 Protein (TNPO3 or TRN-SR2)

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Effects of IRF5 Lupus Risk Haplotype on Pathways Predicted to Influence B Cell Functions

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Monocytes from Irf5-/- Mice Have an Intrinsic Defect in Their Response to Pristane-Induced Lupus

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IRF5 Risk Polymorphisms Contribute to Interindividual Variance in Pattern Recognition Receptor-Mediated Cytokine Secretion in Human Monocyte-Derived Cells

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IRF5 gene polymorphisms in melanoma

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Presenting ENCODE

(2012) Magdalena Skipper et al.   NATURE

Bayesian refinement of association signals for 14 loci in 3 common diseases

(2012) Julian B Maller et al.   NATURE GENETICS

IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus

(2011) Timothy B Niewold et al.   ANNALS OF THE RHEUMATIC DISEASES

Interferon regulatory factor 5 is critical for the development of lupus in MRL/lpr mice

(2011) Yoshifumi Tada et al.   ARTHRITIS AND RHEUMATISM

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

(2011) Carl A Anderson et al.   NATURE GENETICS

Interferon regulatory factor 5 gene polymorphism confers risk to several rheumatic diseases and correlates with expression of alternative thymic transcripts

(2011) G. B. N. Nordang et al.   RHEUMATOLOGY

Replication of GWAS-identified systemic lupus erythematosus susceptibility genes affirms B-cell receptor pathway signalling and strengthens the role of IRF5 in disease susceptibility in a Northern European population

(2011) T. M. Jarvinen et al.   RHEUMATOLOGY

Cis-regulation of IRF5 expression is unable to fully account for systemic lupus erythematosus association: analysis of multiple experiments with lymphoblastoid cell lines

(2011) Elisa Alonso-Perez et al.   ARTHRITIS RESEARCH & THERAPY

Identification of a Systemic Lupus Erythematosus Susceptibility Locus at 11p13 between PDHX and CD44 in a Multiethnic Study

(2010) Christopher J. Lessard et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Exon 6 variants carried on systemic lupus erythematosus (SLE) risk haplotypes modulate IRF5 function

(2010) Feng Wen et al.   AUTOIMMUNITY

Promoter Insertion/Deletion in the IRF5 Gene Is Highly Associated with Susceptibility to Systemic Lupus Erythematosus in Distinct Populations, But Exerts a Modest Effect on Gene Expression in Peripheral Blood Mononuclear Cells

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Integrating common and rare genetic variation in diverse human populations

(2010)   NATURE

Variants at IRF5-TNPO3, 17q12-21 and MMEL1 are associated with primary biliary cirrhosis

(2010) Gideon M Hirschfield et al.   NATURE GENETICS

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

(2010) Eli A Stahl et al.   NATURE GENETICS

Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus

(2010) Timothy R D J Radstake et al.   NATURE GENETICS

Association of IRF5 gene polymorphisms and lupus nephritis in a Chinese population

(2010) LIANXIANG QIN et al.   NEPHROLOGY

The Lupus Family Registry and Repository

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Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus

(2010) Wanling Yang et al.   PLoS Genetics

Association of IRF5 polymorphisms with activation of the interferon   pathway

(2009) O. J. Rullo et al.   ANNALS OF THE RHEUMATIC DISEASES

The CGGGG insertion/deletion polymorphism of theIRF5promoter is a strong risk factor for primary Sjögren's syndrome

(2009) Corinne Miceli-Richard et al.   ARTHRITIS AND RHEUMATISM

Association Between IRF-5 Polymorphisms and Risk of Acute Coronary Syndrome

(2009) Jing-Han Fan et al.   DNA AND CELL BIOLOGY

A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

(2009) Vesela Gateva et al.   NATURE GENETICS

Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus

(2009) Jian-Wen Han et al.   NATURE GENETICS

Bayesian statistical methods for genetic association studies

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Estimating Local Ancestry in Admixed Populations

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Variants of the Interferon Regulatory Factor 5 Gene Regulate Expression of IRF5 mRNA in Atherosclerotic Tissue But Are Not Associated With Myocardial Infarction

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Association ofIRF5 polymorphisms with systemic lupus erythematosus in a Japanese population: Support for a crucial role of intron 1 polymorphisms

(2008) Aya Kawasaki et al.   ARTHRITIS AND RHEUMATISM

Association of the IRF5 risk haplotype with high serum interferon-α activity in systemic lupus erythematosus patients

(2008) Timothy B. Niewold et al.   ARTHRITIS AND RHEUMATISM

Interferon regulatory factor-5 is genetically associated with systemic lupus erythematosus in African Americans

(2008) J A Kelly et al.   GENES AND IMMUNITY

A panel of ancestry informative markers for estimating individual biogeographical ancestry and admixture from four continents: utility and applications

(2008) Indrani Halder et al.   HUMAN MUTATION

Primary biliary cirrhosis in Asians: Less common than in Europeans, but just as depressing

(2008) Geoffrey C Farrell   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

(2008) John B Harley et al.   NATURE GENETICS

UniPROBE: an online database of protein binding microarray data on protein-DNA interactions

(2008) D. E. Newburger et al.   NUCLEIC ACIDS RESEARCH