Systematic annotation of celiac disease loci refines pathological pathways and suggests a genetic explanation for increased interferon-gamma levels

Innate Immune Activity Conditions the Effect of Regulatory Variants upon Monocyte Gene Expression

(2014) B. P. Fairfax et al.   SCIENCE

Mapping of Immune-Mediated Disease Genes

(2013) Isis Ricaño-Ponce et al.   Annual Review of Genomics and Human Genetics

Human SNP Links Differential Outcomes in Inflammatory and Infectious Disease to a FOXO3-Regulated Pathway

(2013) James C. Lee et al.   CELL

Compromised quality of life in patients with both Type 1 diabetes mellitus and coeliac disease

(2013) S. F. Bakker et al.   DIABETIC MEDICINE

Improving coeliac disease risk prediction by testing non-HLA variants additional to HLA variants

(2013) Jihane Romanos et al.   GUT

Fine mapping of the celiac disease-associated LPP locus reveals a potential functional variant

(2013) Rodrigo Almeida et al.   HUMAN MOLECULAR GENETICS

Global Chromatin State Analysis Reveals Lineage-Specific Enhancers during the Initiation of Human T helper 1 and T helper 2 Cell Polarization

(2013) R. David Hawkins et al.   IMMUNITY

BACH2 represses effector programs to stabilize Treg-mediated immune homeostasis

(2013) Rahul Roychoudhuri et al.   NATURE

Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans

(2013) Sanne P. Smeekens et al.   Nature Communications

Human Disease-Associated Genetic Variation Impacts Large Intergenic Non-Coding RNA Expression

(2013) Vinod Kumar et al.   PLoS Genetics

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Identification of early gene expression changes during human Th17 cell differentiation

(2012) S. Tuomela et al.   BLOOD

An integrative computational systems biology approach identifies differentially regulated dynamic transcriptome signatures which drive the initiation of human T helper cell differentiation

(2012) Tarmo Äijö et al.   BMC GENOMICS

Linking disease associations with regulatory information in the human genome

(2012) M. A. Schaub et al.   GENOME RESEARCH

Annotation of functional variation in personal genomes using RegulomeDB

(2012) A. P. Boyle et al.   GENOME RESEARCH

Celiac Disease: An Immunological Jigsaw

(2012) Bertrand Meresse et al.   IMMUNITY

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

High abundance of plasma cells secreting transglutaminase 2–specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions

(2012) Roberto Di Niro et al.   NATURE MEDICINE

Integration of GWAS SNPs and tissue specific expression profiling reveal discrete eQTLs for human traits in blood and brain

(2012) Dena G. Hernandez et al.   NEUROBIOLOGY OF DISEASE

From genome-wide association studies to disease mechanisms: celiac disease as a model for autoimmune diseases

(2012) Vinod Kumar et al.   Seminars in Immunopathology

Unraveling the Regulatory Mechanisms Underlying Tissue-Dependent Genetic Variation of Gene Expression

(2012) Jingyuan Fu et al.   PLoS Genetics

Mapping and analysis of chromatin state dynamics in nine human cell types

(2011) Jason Ernst et al.   NATURE

Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

(2011) Gosia Trynka et al.   NATURE GENETICS

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

Review: Nutritional and Dietary Aspects of Celiac Disease

(2011) Álvaro García-Manzanares et al.   NUTRITION IN CLINICAL PRACTICE

Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology

(2011) Elizabeth J. Rossin et al.   PLoS Genetics

Genome-wide Profiling of Interleukin-4 and STAT6 Transcription Factor Regulation of Human Th2 Cell Programming

(2010) Laura L. Elo et al.   IMMUNITY

Multiple common variants for celiac disease influencing immune gene expression

(2010) Patrick C A Dubois et al.   NATURE GENETICS

The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored

(2010) D. Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

TH17 (and TH1) signatures of intestinal biopsies of CD patients in response to gliadin

(2009) Ainara Castellanos-Rubio et al.   AUTOIMMUNITY

Using biological networks to search for interacting loci in genome-wide association studies

(2009) Mathieu Emily et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Using genome-wide pathway analysis to unravel the etiology of complex diseases

(2009) Clara C. Elbers et al.   GENETIC EPIDEMIOLOGY

Pathway and network-based analysis of genome-wide association studies in multiple sclerosis

(2009) S. E. Baranzini et al.   HUMAN MOLECULAR GENETICS

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

(2009) L. A. Hindorff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identifying Relationships among Genomic Disease Regions: Predicting Genes at Pathogenic SNP Associations and Rare Deletions

(2009) Soumya Raychaudhuri et al.   PLoS Genetics

Pathways-based analyses of whole-genome association study data in bipolar disorder reveal genes mediating ion channel activity and synaptic neurotransmission

(2008) Kathleen Askland et al.   HUMAN GENETICS

Newly identified genetic risk variants for celiac disease related to the immune response

(2008) Karen A Hunt et al.   NATURE GENETICS

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH