Intermediate filament protein accumulation in motor neurons derived from giant axonal neuropathy iPSCs rescued by restoration of gigaxonin

Restoration of Cytoskeleton Homeostasis After Gigaxonin Gene Transfer for Giant Axonal Neuropathy

(2013) Silke Mussche et al.   HUMAN GENE THERAPY

Giant axonal neuropathy–associated gigaxonin mutations impair intermediate filament protein degradation

(2013) Saleemulla Mahammad et al.   JOURNAL OF CLINICAL INVESTIGATION

Proteomic analysis in giant axonal neuropathy: New insights into disease mechanisms

(2012) Silke Mussche et al.   MUSCLE & NERVE

Sensory-motor deficits and neurofilament disorganization in gigaxonin-null mice

(2011) Thibault Ganay et al.   Molecular Neurodegeneration

Modelling schizophrenia using human induced pluripotent stem cells

(2011) Kristen J. Brennand et al.   NATURE

A functionally characterized test set of human induced pluripotent stem cells

(2011) Gabriella L Boulting et al.   NATURE BIOTECHNOLOGY

Genetic correction and analysis of induced pluripotent stem cells from a patient with gyrate atrophy

(2011) S. E. Howden et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells

(2010) Maria C.N. Marchetto et al.   CELL

What can pluripotent stem cells teach us about neurodegenerative diseases?

(2010) Hynek Wichterle et al.   NATURE NEUROSCIENCE

Gigaxonin controls vimentin organization through a tubulin chaperone-independent pathway

(2009) D. W. Cleveland et al.   HUMAN MOLECULAR GENETICS

Dysfunctions of neuronal and glial intermediate filaments in disease

(2009) Ronald K.H. Liem et al.   JOURNAL OF CLINICAL INVESTIGATION

Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs

(2009) Gabsang Lee et al.   NATURE

A chemical platform for improved induction of human iPSCs

(2009) Tongxiang Lin et al.   NATURE METHODS

Disease-Specific Induced Pluripotent Stem Cells

(2008) In-Hyun Park et al.   CELL

Modest loss of peripheral axons, muscle atrophy and formation of brain inclusions in mice with targeted deletion of gigaxonin exon 1

(2008) Florence Dequen et al.   JOURNAL OF NEUROCHEMISTRY

Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons

(2008) J. T. Dimos et al.   SCIENCE