A sequence variant associated with sortilin-1 (SORT1) on 1p13.3 is independently associated with abdominal aortic aneurysm
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Title
A sequence variant associated with sortilin-1 (SORT1) on 1p13.3 is independently associated with abdominal aortic aneurysm
Authors
Keywords
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Journal
HUMAN MOLECULAR GENETICS
Volume 22, Issue 14, Pages 2941-2947
Publisher
Oxford University Press (OUP)
Online
2013-03-28
DOI
10.1093/hmg/ddt141
References
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- Association of the single nucleotide polymorphism rs599839 in the vicinity of the sortilin 1 gene with LDL and triglyceride metabolism, coronary heart disease and myocardial infarction
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- Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL-uptake and serum LDL levels which translates to the risk of coronary artery disease
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- Identification of a genetic variant associated with abdominal aortic aneurysms on chromosome 3p12.3 by genome wide association
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- Circulating Markers of Abdominal Aortic Aneurysm Presence and Progression
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- The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm
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