Chemical genetics unveils a key role of mitochondrial dynamics, cytochrome c release and IP3R activity in muscular dystrophy

Recombinant Expression, Biophysical Characterization, and Cardiolipin-Induced Changes of Two Caenorhabditis elegans Cytochrome c Proteins

(2013) Amber J. Vincelli et al.   BIOCHEMISTRY

Defects in mitochondrial localization and ATP synthesis in the mdx mouse model of Duchenne muscular dystrophy are not alleviated by PDE5 inhibition

(2012) J. M. Percival et al.   HUMAN MOLECULAR GENETICS

Mitochondrial disorders as windows into an ancient organelle

(2012) Scott B. Vafai et al.   NATURE

Fusion and Fission: Interlinked Processes Critical for Mitochondrial Health

(2011) David C. Chan   Annual Review of Genetics

Evaluation of exon-skipping strategies for Duchenne muscular dystrophy utilizing dystrophin-deficient zebrafish

(2011) Joachim Berger et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Caenorhabditis elegans as a chemical screening tool for the study o f neuromuscular disorders. Manual and semi-automated methods

(2011) Jean Giacomotto et al.   METHODS

Pre-clinical study of 21 approved drugs in the mdx mouse

(2011) Maïté Carre-Pierrat et al.   NEUROMUSCULAR DISORDERS

Mitochondrial involvement in cell death of non-mammalian eukaryotes

(2010) Eltyeb Abdelwahid et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

High-throughput screening and small animal models, where are we?

(2010) Jean Giacomotto et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1

(2010) Frits Kamp et al.   EMBO JOURNAL

The mitochondrial permeability transition from yeast to mammals

(2010) Luca Azzolin et al.   FEBS LETTERS

Treatment of Duchenne muscular dystrophy with ciclosporin A: a randomised, double-blind, placebo-controlled multicentre trial

(2010) Janbernd Kirschner et al.   LANCET NEUROLOGY

The cyclophilin inhibitor Debio 025 normalizes mitochondrial function, muscle apoptosis and ultrastructural defects inCol6a1−/−myopathic mice

(2009) T Tiepolo et al.   BRITISH JOURNAL OF PHARMACOLOGY

Evaluation of the therapeutic potential of carbonic anhydrase inhibitors in two animal models of dystrophin deficient muscular dystrophy

(2009) J. Giacomotto et al.   HUMAN MOLECULAR GENETICS

Genetic ablation of cyclophilin D rescues mitochondrial defects and prevents muscle apoptosis in collagen VI myopathic mice

(2009) Elena Palma et al.   HUMAN MOLECULAR GENETICS

Real-time imaging of mitochondria in transgenic zebrafish expressing mitochondrially targeted GFP

(2008) Min Jung Kim et al.   BIOTECHNIQUES

Investigation of Debio 025, a cyclophilin inhibitor, in the dystrophic mdx mouse, a model for Duchenne muscular dystrophy

(2008) J Reutenauer et al.   BRITISH JOURNAL OF PHARMACOLOGY

CED-9 and mitochondrial homeostasis in C. elegans muscle

(2008) F. J. Tan et al.   JOURNAL OF CELL SCIENCE

Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy

(2008) Douglas P Millay et al.   NATURE MEDICINE

Phospholipase C-ε Regulates Epidermal Morphogenesis in Caenorhabditis elegans

(2008) Rafael P. Vázquez-Manrique et al.   PLoS Genetics

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL