Loss of caveolin-1 expression in knock-in mouse model of Huntington's disease suppresses pathophysiology in vivo

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Caveolin-1 is ubiquitinated and targeted to intralumenal vesicles in endolysosomes for degradation

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Altered cholesterol homeostasis contributes to enhanced excitotoxicity in Huntington’s disease

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Cholesterol Defect Is Marked across Multiple Rodent Models of Huntington's Disease and Is Manifest in Astrocytes

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Huntingtin coordinates the dynein-mediated dynamic positioning of endosomes and lysosomes

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Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease

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Cholesterol involvement in the pathogenesis of neurodegenerative diseases

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Mutant Huntingtin Impairs Post-Golgi Trafficking to Lysosomes by Delocalizing Optineurin/Rab8 Complex from the Golgi Apparatus

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