Loss of c-Jun N-terminal kinase-interacting protein-1 does not affect axonal transport of the amyloid precursor protein or Aβ production

Amyloid-  Peptide Oligomers Disrupt Axonal Transport through an NMDA Receptor-Dependent Mechanism That Is Mediated by Glycogen Synthase Kinase 3  in Primary Cultured Hippocampal Neurons

(2013) H. Decker et al.   JOURNAL OF NEUROSCIENCE

Axonal transport deficits and neurodegenerative diseases

(2013) Stéphanie Millecamps et al.   NATURE REVIEWS NEUROSCIENCE

Amyotrophic lateral sclerosis-associated mutant VAPBP56S perturbs calcium homeostasis to disrupt axonal transport of mitochondria

(2012) G. M. Morotz et al.   HUMAN MOLECULAR GENETICS

Enhanced  -secretase processing alters APP axonal transport and leads to axonal defects

(2012) E. M. Rodrigues et al.   HUMAN MOLECULAR GENETICS

Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates A  production

(2012) A. Vagnoni et al.   HUMAN MOLECULAR GENETICS

Multiple γ-secretase product peptides are coordinately increased in concentration in the cerebrospinal fluid of a subpopulation of sporadic Alzheimer’s disease subjects

(2012) Saori Hata et al.   Molecular Neurodegeneration

A Small Peptide Sequence is Sufficient for Initiating Kinesin-1 Activation Through Part of TPR Region of KLC1

(2012) Takanori Kawano et al.   TRAFFIC

Calsyntenin-1 shelters APP from proteolytic processing during anterograde axonal transport

(2012) M. Steuble et al.   Biology Open

GULP1 is a novel APP-interacting protein that alters APP processing

(2011) Candy Yan Hao et al.   BIOCHEMICAL JOURNAL

A kinesin-1 binding motif in vaccinia virus that is widespread throughout the human genome

(2011) Mark P Dodding et al.   EMBO JOURNAL

Phosphorylation of kinesin light chain 1 at serine 460 modulates binding and trafficking of calsyntenin-1

(2011) A. Vagnoni et al.   JOURNAL OF CELL SCIENCE

Axonal transport of APP and the spatial regulation of APP cleavage and function in neuronal cells

(2011) Silke Brunholz et al.   EXPERIMENTAL BRAIN RESEARCH

Alternative processing of γ-secretase substrates in common forms of mild cognitive impairment and alzheimer's disease: Evidence for γ-secretase dysfunction

(2010) Saori Hata et al.   ANNALS OF NEUROLOGY

A  Oligomers Cause Localized Ca2+ Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines

(2010) H. Zempel et al.   JOURNAL OF NEUROSCIENCE

The secretases: enzymes with therapeutic potential in Alzheimer disease

(2010) Bart De Strooper et al.   Nature Reviews Neurology

Amyloid-β-Derived Diffusible Ligands Cause Impaired Axonal Transport of Mitochondria in Neurons

(2010) Xinglong Wang et al.   Neurodegenerative Diseases

The functional neurophysiology of the amyloid precursor protein (APP) processing pathway

(2010) A.D. Randall et al.   NEUROPHARMACOLOGY

X11  rescues memory and long-term potentiation deficits in Alzheimer's disease APPswe Tg2576 mice

(2009) J. C. Mitchell et al.   HUMAN MOLECULAR GENETICS

Phosphorylated Tau Interacts with c-Jun N-terminal Kinase-interacting Protein 1 (JIP1) in Alzheimer Disease

(2009) Lars M. Ittner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid precursor protein 695 associates with assembled NR2A- and NR2B-containing NMDA receptors to result in the enhancement of their cell surface delivery

(2009) Sarah L. Cousins et al.   JOURNAL OF NEUROCHEMISTRY

Axonal Stress Kinase Activation and Tau Misbehavior Induced by Kinesin-1 Transport Defects

(2009) T. L. Falzone et al.   JOURNAL OF NEUROSCIENCE

Axonal Transport Defects in Neurodegenerative Diseases

(2009) G. A. Morfini et al.   JOURNAL OF NEUROSCIENCE

APP Anterograde Transport Requires Rab3A GTPase Activity for Assembly of the Transport Vesicle

(2009) A. Szodorai et al.   JOURNAL OF NEUROSCIENCE

Kinesin superfamily motor proteins and intracellular transport

(2009) Nobutaka Hirokawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta

(2009) G. Pigino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calsyntenins Mediate TGN Exit of APP in a Kinesin-1-Dependent Manner

(2009) Alexander Ludwig et al.   TRAFFIC

Role of Axonal Transport in Neurodegenerative Diseases

(2008) Kurt J. De Vos et al.   Annual Review of Neuroscience

The JIP1 Scaffold Protein Regulates Axonal Development in Cortical Neurons

(2008) Federico Dajas-Bailador et al.   CURRENT BIOLOGY

Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain

(2003) H. F. Dovey et al.   JOURNAL OF NEUROCHEMISTRY