Micro-dystrophin and follistatin co-delivery restores muscle function in aged DMD model

AAV-mediated Overexpression of Human α7 Integrin Leads to Histological and Functional Improvement in Dystrophic Mice

(2013) Kristin N Heller et al.   MOLECULAR THERAPY

Microdystrophin Ameliorates Muscular Dystrophy in the Canine Model of Duchenne Muscular Dystrophy

(2013) Jin-Hong Shin et al.   MOLECULAR THERAPY

Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatin

(2012) Catherine E. Winbanks et al.   JOURNAL OF CELL BIOLOGY

Glucocorticoid-Treated Mice Are an Inappropriate Positive Control for Long-Term Preclinical Studies in the mdx Mouse

(2012) Arpana Sali et al.   PLoS One

Dual exon skipping in myostatin and dystrophin for Duchenne muscular dystrophy

(2011) Dwi U Kemaladewi et al.   BMC Medical Genomics

Decreased specific force and power production of muscle fibers from myostatin-deficient mice are associated with a suppression of protein degradation

(2011) Christopher L. Mendias et al.   JOURNAL OF APPLIED PHYSIOLOGY

Pre-clinical study of 21 approved drugs in the mdx mouse

(2011) Maïté Carre-Pierrat et al.   NEUROMUSCULAR DISORDERS

Combination of Myostatin Pathway Interference and Dystrophin Rescue Enhances Tetanic and Specific Force in Dystrophic mdx Mice

(2010) Julie Dumonceaux et al.   MOLECULAR THERAPY

Gene Therapy of mdx Mice With Large Truncated Dystrophins Generated by Recombination Using rAAV6

(2010) Guy L Odom et al.   MOLECULAR THERAPY

Aminoglycoside-induced mutation suppression (stop codon readthrough) as a therapeutic strategy for Duchenne muscular dystrophy

(2010) Vinod Malik et al.   Therapeutic Advances in Neurological Disorders

Follistatin induces muscle hypertrophy through satellite cell proliferation and inhibition of both myostatin and activin

(2009) Hélène Gilson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Dystrophins carrying spectrin-like repeats 16 and 17 anchor nNOS to the sarcolemma and enhance exercise performance in a mouse model of muscular dystrophy

(2009) Yi Lai et al.   JOURNAL OF CLINICAL INVESTIGATION

Effects of prednisolone on skeletal muscle contractility inmdxmice

(2009) Kristen A. Baltgalvis et al.   MUSCLE & NERVE

Inhibition of myostatin with emphasis on follistatin as a therapy for muscle disease

(2009) Louise R. Rodino-Klapac et al.   MUSCLE & NERVE

Follistatin Gene Delivery Enhances Muscle Growth and Strength in Nonhuman Primates

(2009) J. Kota et al.   Science Translational Medicine

Overexpression of Galgt2 in skeletal muscle prevents injury resulting from eccentric contractions in both mdx and wild-type mice

(2008) Paul T. Martin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Myostatin Propeptide Gene Delivery by Adeno-Associated Virus Serotype 8 Vectors Enhances Muscle Growth and Ameliorates Dystrophic Phenotypes in mdx Mice

(2008) Chunping Qiao et al.   HUMAN GENE THERAPY

Myostatin Directly Regulates Skeletal Muscle Fibrosis

(2008) Zhao Bo Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Long-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitors

(2008) A. M. Haidet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transgenic expression of a myostatin inhibitor derived from follistatin increases skeletal muscle mass and ameliorates dystrophic pathology in mdx mice

(2007) Masashi Nakatani et al.   FASEB JOURNAL