FOXO3 determines the accumulation of α-synuclein and controls the fate of dopaminergic neurons in the substantia nigra

Induction of macroautophagy by exogenously introduced calcium

(2014) Wentao Gao et al.   Autophagy

Consideration about negative controls for LC3 and expression vectors for four colored fluorescent protein-LC3 negative controls

(2014) Isei Tanida et al.   Autophagy

Utilizing flow cytometry to monitor autophagy in living mammalian cells

(2014) Elena Shvets et al.   Autophagy

Oxidative stress-induced posttranslational modifications of alpha-synuclein: Specific modification of alpha-synuclein by 4-hydroxy-2-nonenal increases dopaminergic toxicity

(2013) Wei Xiang et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

FOXO3A directs a protective autophagy program in haematopoietic stem cells

(2013) Matthew R. Warr et al.   NATURE

Nigrostriatal overabundance of α-synuclein leads to decreased vesicle density and deficits in dopamine release that correlate with reduced motor activity

(2012) Meret Nora Gaugler et al.   ACTA NEUROPATHOLOGICA

Lysine methylation of FOXO3 regulates oxidative stress-induced neuronal cell death

(2012) Qi Xie et al.   EMBO REPORTS

Phosphorylation of α-Synuclein Protein at Ser-129 Reduces Neuronal Dysfunction by Lowering Its Membrane Binding Property inCaenorhabditis elegans

(2012) Tomoki Kuwahara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modulation of glutamine metabolism by the PI(3)K–PKB–FOXO network regulates autophagy

(2012) Kristan E. van der Vos et al.   NATURE CELL BIOLOGY

Gene Expression Profiles in Parkinson Disease Prefrontal Cortex Implicate FOXO1 and Genes under Its Transcriptional Regulation

(2012) Alexandra Dumitriu et al.   PLoS Genetics

Mutant A53T α-Synuclein Induces Neuronal Death by Increasing Mitochondrial Autophagy

(2011) Vinay Choubey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of genetic variants in human longevity

(2010) Wen-Hung Chung et al.   AGEING RESEARCH REVIEWS

New insights into the role of mitochondrial dysfunction and protein aggregation in Parkinson's disease

(2010) Weilin Xie et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Activation of FoxO by LRRK2 induces expression of proapoptotic proteins and alters survival of postmitotic dopaminergic neuron in Drosophila

(2010) Tomoko Kanao et al.   HUMAN MOLECULAR GENETICS

Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity

(2010) Ying Zhao et al.   NATURE CELL BIOLOGY

Reduced IGF-1 Signaling Delays Age-Associated Proteotoxicity in Mice

(2009) Ehud Cohen et al.   CELL

FoxOs Cooperatively Regulate Diverse Pathways Governing Neural Stem Cell Homeostasis

(2009) Ji-hye Paik et al.   Cell Stem Cell

FoxO3 Regulates Neural Stem Cell Homeostasis

(2009) Valérie M. Renault et al.   Cell Stem Cell

FoxO Transcription Factors Promote Autophagy in Cardiomyocytes

(2009) Arunima Sengupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

α-Synuclein and neuronal cell death

(2009) Mark R Cookson   Molecular Neurodegeneration

Targeted overexpression of the parkin substrate Pael-R in the nigrostriatal system of adult rats to model Parkinson's disease

(2009) Julien Dusonchet et al.   NEUROBIOLOGY OF DISEASE

FOXO3a-dependent regulation of Pink1 (Park6) mediates survival signaling in response to cytokine deprivation

(2009) Y. Mei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuronal pigmented autophagic vacuoles: lipofuscin, neuromelanin, and ceroid as macroautophagic responses during aging and disease

(2008) David Sulzer et al.   JOURNAL OF NEUROCHEMISTRY