Hippocampal dysfunction in the Euchromatin histone methyltransferase 1 heterozygous knockout mouse model for Kleefstra syndrome

Disruption of an EHMT1-Associated Chromatin-Modification Module Causes Intellectual Disability

(2012) Tjitske Kleefstra et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Sequencing Chromosomal Abnormalities Reveals Neurodevelopmental Loci that Confer Risk across Diagnostic Boundaries

(2012) Michael E. Talkowski et al.   CELL

A Mouse Model for MeCP2 Duplication Syndrome: MeCP2 Overexpression Impairs Learning and Memory and Synaptic Transmission

(2012) E. S. Na et al.   JOURNAL OF NEUROSCIENCE

HDAC1 Regulates Fear Extinction in Mice

(2012) S. Bahari-Javan et al.   JOURNAL OF NEUROSCIENCE

G9a/GLP Histone Lysine Dimethyltransferase Complex Activity in the Hippocampus and the Entorhinal Cortex Is Required for Gene Activation and Silencing during Memory Consolidation

(2012) S. Gupta-Agarwal et al.   JOURNAL OF NEUROSCIENCE

Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations

(2012) Brian J. O’Roak et al.   NATURE

Genetic and Epigenetic Networks in Intellectual Disabilities

(2011) Hans van Bokhoven   Annual Review of Genetics

Differential regulation of spontaneous and evoked neurotransmitter release at central synapses

(2011) Denise MO Ramirez et al.   CURRENT OPINION IN NEUROBIOLOGY

Dysregulation of Rho GTPases in the αPix/Arhgef6 mouse model of X-linked intellectual disability is paralleled by impaired structural and synaptic plasticity and cognitive deficits

(2011) Ger J.A. Ramakers et al.   HUMAN MOLECULAR GENETICS

Effects of Elevation of Brain Magnesium on Fear Conditioning, Fear Extinction, and Synaptic Plasticity in the Infralimbic Prefrontal Cortex and Lateral Amygdala

(2011) N. Abumaria et al.   JOURNAL OF NEUROSCIENCE

When Is the Hippocampus Involved in Recognition Memory?

(2011) G. R. I. Barker et al.   JOURNAL OF NEUROSCIENCE

Emerging major synaptic signaling pathways involved in intellectual disability

(2011) A Pavlowsky et al.   MOLECULAR PSYCHIATRY

De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia

(2011) G Kirov et al.   MOLECULAR PSYCHIATRY

Mutations causing syndromic autism define an axis of synaptic pathophysiology

(2011) Benjamin D. Auerbach et al.   NATURE

Epigenetics in the mature mammalian brain: Effects on behavior and synaptic transmission

(2011) Erika D. Nelson et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Rapid Synthesis of the X-Linked Mental Retardation Protein OPHN1 Mediates mGluR-Dependent LTD through Interaction with the Endocytic Machinery

(2011) Nael Nadif Kasri et al.   NEURON

Epigenetic Regulation of Learning and Memory by Drosophila EHMT/G9a

(2011) Jamie M. Kramer et al.   PLOS BIOLOGY

Sensory processing and stereotypical and repetitive behaviour in children with autism and intellectual disability

(2010) Annette V. Joosten et al.   Australian Occupational Therapy Journal

Neuronal circuits of fear extinction

(2010) Cyril Herry et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Membrane-Associated Glucocorticoid Activity Is Necessary for Modulation of Long-Term Memory via Chromatin Modification

(2010) B. Roozendaal et al.   JOURNAL OF NEUROSCIENCE

Histone Methylation Regulates Memory Formation

(2010) S. Gupta et al.   JOURNAL OF NEUROSCIENCE

A Subset of the Histone H3 Lysine 9 Methyltransferases Suv39h1, G9a, GLP, and SETDB1 Participate in a Multimeric Complex

(2010) Lauriane Fritsch et al.   MOLECULAR CELL

Fragile X mental retardation protein in learning-related synaptic plasticity

(2010) Valentina Mercaldo et al.   MOLECULES AND CELLS

Animal models of neuropsychiatric disorders

(2010) Eric J Nestler et al.   NATURE NEUROSCIENCE

Disruption of the epigenetic code: An emerging mechanism in mental retardation

(2010) Hans van Bokhoven et al.   NEUROBIOLOGY OF DISEASE

Behavioral phenotype in the 9q subtelomeric deletion syndrome: A report about two adult patients

(2009) Willem M.A. Verhoeven et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Reduced exploration, increased anxiety, and altered social behavior: Autistic-like features of euchromatin histone methyltransferase 1 heterozygous knockout mice

(2009) Monique C.M. Balemans et al.   BEHAVIOURAL BRAIN RESEARCH

Context conditioning and extinction in humans: differential contribution of the hippocampus, amygdala and prefrontal cortex

(2009) Simone Lang et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Qualitatively different modes of perirhinal–hippocampal engagement when rats explore novel vs. familiar objects as revealed by c-Fos imaging

(2009) Mathieu M. Albasser et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The Rho-linked mental retardation protein oligophrenin-1 controls synapse maturation and plasticity by stabilizing AMPA receptors

(2009) N. Nadif Kasri et al.   GENES & DEVELOPMENT

Further clinical and molecular delineation of the 9q subtelomeric deletion syndrome supports a major contribution of EHMT1 haploinsufficiency to the core phenotype

(2009) T Kleefstra et al.   JOURNAL OF MEDICAL GENETICS

Dendritic spine pathologies in hippocampal pyramidal neurons from Rett syndrome brain and after expression of Rett-associated MECP2 mutations

(2009) Christopher A. Chapleau et al.   NEUROBIOLOGY OF DISEASE

Control of Cognition and Adaptive Behavior by the GLP/G9a Epigenetic Suppressor Complex

(2009) Anne Schaefer et al.   NEURON

Differing presynaptic contributions to LTP and associative learning in behaving mice

(2009) Neolia Madronal   Frontiers in Behavioral Neuroscience

Criteria for validating mouse models of psychiatric diseases

(2008) Kathryn K. Chadman et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Pavlovian fear conditioning as a behavioral assay for hippocampus and amygdala function: cautions and caveats

(2008) Stephen Maren   EUROPEAN JOURNAL OF NEUROSCIENCE

Genetic and epigenetic defects in mental retardation

(2008) Jamie M. Kramer et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY