Polycystin-1 regulates the stability and ubiquitination of transcription factor Jade-1

Polycystin-dependent fluid flow sensing targets histone deacetylase 5 to prevent the development of renal cysts

(2010) S. Xia et al.   DEVELOPMENT

Direct Ubiquitination of β-Catenin by Siah-1 and Regulation by the Exchange Factor TBL1

(2010) Yoana N. Dimitrova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Failure to ubiquitinate c-Met leads to hyperactivation of mTOR signaling in a mouse model of autosomal dominant polycystic kidney disease

(2010) Shan Qin et al.   JOURNAL OF CLINICAL INVESTIGATION

Cystic kidney disease: the role of Wnt signaling

(2010) Madeline A. Lancaster et al.   TRENDS IN MOLECULAR MEDICINE

Conditional Mutation of Pkd2 Causes Cystogenesis and Upregulates  -Catenin

(2009) I. Kim et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models

(2009) Y. Cao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

β-catenin gets jaded and von Hippel-Lindau is to blame

(2009) Jason D. Berndt et al.   TRENDS IN BIOCHEMICAL SCIENCES

Polycystin-1 C-terminal tail associates with β-catenin and inhibits canonical Wnt signaling

(2008) Mark Lal et al.   HUMAN MOLECULAR GENETICS

Neutrophil gelatinase-associated lipocalin suppresses cyst growth by Pkd1 null cells in vitro and in vivo

(2008) Feng Wei et al.   KIDNEY INTERNATIONAL

Jade-1 inhibits Wnt signalling by ubiquitylating β-catenin and mediates Wnt pathway inhibition by pVHL

(2008) Vipul C. Chitalia et al.   NATURE CELL BIOLOGY