Trans-chromosomic mice containing a human CYP3A cluster for prediction of xenobiotic metabolism in humans

Expression and Regulation of Human Fetal-Specific CYP3A7 in Mice

(2012) Xiao-Yan Pang et al.   ENDOCRINOLOGY

Quantitative Prediction of Human Pregnane X Receptor and Cytochrome P450 3A4 Mediated Drug-Drug Interaction in a Novel Multiple Humanized Mouse Line

(2011) M. Hasegawa et al.   MOLECULAR PHARMACOLOGY

Human Artificial Chromosomes for Gene Delivery and the Development of Animal Models

(2011) Yasuhiro Kazuki et al.   MOLECULAR THERAPY

Species Differences in Mechanism-Based Inactivation of CYP3A in Humans, Rats and Mice

(2010) Sasitorn Aueviriyavit et al.   Drug Metabolism and Pharmacokinetics

Simultaneous Absolute Quantification of 11 Cytochrome P450 Isoforms in Human Liver Microsomes by Liquid Chromatography Tandem Mass Spectrometry with In Silico Target Peptide Selection

(2010) Hirotaka Kawakami et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Rat transgenesis via embryonic stem cells electroporated with the Kusabira-orange gene

(2010) Masumi Hirabayashi et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Transfer of human artificial chromosome vectors into stem cells

(2010) Mitsuo Oshimura et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Inhibition and Stimulation of Intestinal and Hepatic CYP3A Activity: Studies in Humanized CYP3A4 Transgenic Mice Using Triazolam

(2009) R. A. B. van Waterschoot et al.   DRUG METABOLISM AND DISPOSITION

Potential Strategies for Minimizing Mechanism-Based Inhibition of Cytochrome P450 3A4

(2008) Shu-Feng Zhou   CURRENT PHARMACEUTICAL DESIGN

A Double Transgenic Mouse Model Expressing Human Pregnane X Receptor and Cytochrome P450 3A4

(2008) X. Ma et al.   DRUG METABOLISM AND DISPOSITION

Post-transcriptional Regulation of Human Pregnane X Receptor by Micro-RNA Affects the Expression of Cytochrome P450 3A4

(2008) Shingo Takagi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A highly Stable and Nonintegrated Human Artificial Chromosome (HAC) Containing the 2.4 Mb Entire Human Dystrophin Gene

(2008) Hidetoshi Hoshiya et al.   MOLECULAR THERAPY

In vivoapproach for the evaluation of mechanism-based inhibition of cytochrome P450 3A in rats

(2008) N. Sekiguchi et al.   XENOBIOTICA

Pharmacokinetics in Drug Discovery

(2007) Ana Ruiz-Garcia et al.   JOURNAL OF PHARMACEUTICAL SCIENCES