Pyrimethamine inhibits adult polycystic kidney disease by modulating STAT signaling pathways

Therapeutic mTOR Inhibition in Autosomal Dominant Polycystic Kidney Disease: What Is the Appropriate Serum Level?

(2010) G. Canaud et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Prospects for mTOR Inhibitor Use in Patients with Polycystic Kidney Disease and Hamartomatous Diseases

(2010) V. E. Torres et al.   Clinical Journal of the American Society of Nephrology

Failure to ubiquitinate c-Met leads to hyperactivation of mTOR signaling in a mouse model of autosomal dominant polycystic kidney disease

(2010) Shan Qin et al.   JOURNAL OF CLINICAL INVESTIGATION

A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy

(2010) Maoyin Pang et al.   KIDNEY INTERNATIONAL

Sirolimus and Kidney Growth in Autosomal Dominant Polycystic Kidney Disease

(2010) Andreas L. Serra et al.   NEW ENGLAND JOURNAL OF MEDICINE

Everolimus in Patients with Autosomal Dominant Polycystic Kidney Disease

(2010) Gerd Walz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evaluation of the effect of pyrimethamine, an anti-malarial drug, on HIV-1 replication

(2010) Raphael M. Oguariri et al.   VIRUS RESEARCH

Toxic tubular injury in kidneys from Pkd1-deletion mice accelerates cystogenesis accompanied by dysregulated planar cell polarity and canonical Wnt signaling pathways

(2009) H. Happe et al.   HUMAN MOLECULAR GENETICS

Renal injury is a third hit promoting rapid development of adult polycystic kidney disease

(2009) Ayumi Takakura et al.   HUMAN MOLECULAR GENETICS

Nifuroxazide inhibits survival of multiple myeloma cells by directly inhibiting STAT3

(2008) E. A. Nelson et al.   BLOOD

Pyrimethamine Induces Apoptosis of Melanoma Cells via a Caspase and Cathepsin Double-Edged Mechanism

(2008) A. M. Giammarioli et al.   CANCER RESEARCH

Intrinsic Epithelial Cells Repair the Kidney after Injury

(2008) Benjamin D. Humphreys et al.   Cell Stem Cell

Pkd1 Inactivation Induced in Adulthood Produces Focal Cystic Disease

(2008) A. Takakura et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Col2-Cre recombinase is co-expressed with endogenous type II collagen in embryonic renal epithelium and drives development of polycystic kidney disease following inactivation of ciliary genes

(2008) Elona Kolpakova-Hart et al.   MATRIX BIOLOGY