Drosophila orthologue of WWOX, the chromosomal fragile site FRA16D tumour suppressor gene, functions in aerobic metabolism and regulates reactive oxygen species

Signaling from membrane receptors to tumor suppressor WW domain-containing oxidoreductase

(2011) Jean-Yun Chang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

IDH1R132 mutation identified in one human melanoma metastasis, but not correlated with metastases to the brain

(2010) Giselle Y. Lopez et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Signatures of mutation and selection in the cancer genome

(2010) Graham R. Bignell et al.   NATURE

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

(2010) F. Weinberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of the Kinases RIP1 and RIP3 in TNF-Induced Necrosis

(2010) P. Vandenabeele et al.   Science Signaling

Fragile gene product, Fhit, in oxidative and replicative stress responses

(2009) Hiroshi Okumura et al.   CANCER SCIENCE

Nox proteins in signal transduction

(2009) David I. Brown et al.   FREE RADICAL BIOLOGY AND MEDICINE

A spontaneous mutation of theWwoxgene and audiogenic seizures in rats with lethal dwarfism and epilepsy

(2009) H. Suzuki et al.   GENES BRAIN AND BEHAVIOR

The role of cellular oxidative stress in regulating glycolysis energy metabolism in hepatoma cells

(2009) Dong-yun Shi et al.   Molecular Cancer

Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia Genome

(2009) Elaine R. Mardis et al.   NEW ENGLAND JOURNAL OF MEDICINE

IDH1andIDH2Mutations in Gliomas

(2009) Hai Yan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Generation and Characterization of Mice Carrying a Conditional Allele of the Wwox Tumor Suppressor Gene

(2009) John H. Ludes-Meyers et al.   PLoS One

Targeted Ablation of the WW Domain-Containing Oxidoreductase Tumor Suppressor Leads to Impaired Steroidogenesis

(2008) Rami I. Aqeilan et al.   ENDOCRINOLOGY

Fhit Interaction with Ferredoxin Reductase Triggers Generation of Reactive Oxygen Species and Apoptosis of Cancer Cells

(2008) Francesco Trapasso et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The WWOX Tumor Suppressor Is Essential for Postnatal Survival and Normal Bone Metabolism

(2008) Rami I. Aqeilan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FlyBase: enhancing Drosophila Gene Ontology annotations

(2008) S. Tweedie et al.   NUCLEIC ACIDS RESEARCH

Induction of hsp70, hsp60, hsp83 and hsp26 and oxidative stress markers in benzene, toluene and xylene exposed Drosophila melanogaster: Role of ROS generation

(2008) Mahendra Pratap Singh et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY