A novel Caenorhabditis elegans allele, smn-1(cb131), mimicking a mild form of spinal muscular atrophy, provides a convenient drug screening platform highlighting new and pre-approved compounds

SAHA ameliorates the SMA phenotype in two mouse models for spinal muscular atrophy

(2010) Markus Riessland et al.   HUMAN MOLECULAR GENETICS

Altered Intracellular Ca2+ Homeostasis in Nerve Terminals of Severe Spinal Muscular Atrophy Mice

(2010) R. Ruiz et al.   JOURNAL OF NEUROSCIENCE

GM1 ganglioside in Parkinson's disease: Results of a five year open study

(2010) Jay S. Schneider et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

SMA CARNI-VAL Trial Part I: Double-Blind, Randomized, Placebo-Controlled Trial of L-Carnitine and Valproic Acid in Spinal Muscular Atrophy

(2010) Kathryn J. Swoboda et al.   PLoS One

Conserved Genes Act as Modifiers of Invertebrate SMN Loss of Function Defects

(2010) Maria Dimitriadi et al.   PLoS Genetics

Fast, automated measurement of nematode swimming (thrashing) without morphometry

(2009) Steven D Buckingham et al.   BMC NEUROSCIENCE

Management of myasthenic conditions: nonimmune issues

(2009) Zohar Argov   CURRENT OPINION IN NEUROLOGY

Sialic acids as regulators of molecular and cellular interactions

(2009) Roland Schauer   CURRENT OPINION IN STRUCTURAL BIOLOGY

An in vitro screening cascade to identify neuroprotective antioxidants in ALS

(2009) Siân C. Barber et al.   FREE RADICAL BIOLOGY AND MEDICINE

Evaluation of the therapeutic potential of carbonic anhydrase inhibitors in two animal models of dystrophin deficient muscular dystrophy

(2009) J. Giacomotto et al.   HUMAN MOLECULAR GENETICS

Impaired Synaptic Vesicle Release and Immaturity of Neuromuscular Junctions in Spinal Muscular Atrophy Mice

(2009) L. Kong et al.   JOURNAL OF NEUROSCIENCE

Sustained-release oral fampridine in multiple sclerosis: a randomised, double-blind, controlled trial

(2009) Andrew D Goodman et al.   LANCET

Spinal muscular atrophy: why do low levels of survival motor neuron protein make motor neurons sick?

(2009) Arthur H. M. Burghes et al.   NATURE REVIEWS NEUROSCIENCE

Valproic acid blocks excitability in SMA type I mouse motor neurons

(2009) Kristen Rak et al.   NEUROBIOLOGY OF DISEASE

Deletion of smn-1, the Caenorhabditis elegans ortholog of the spinal muscular atrophy gene, results in locomotor dysfunction and reduced lifespan

(2008) M. Briese et al.   HUMAN MOLECULAR GENETICS

Strategies for automated analysis of C. elegans locomotion

(2008) Steven D. Buckingham et al.   INVERTEBRATE NEUROSCIENCE

The effect of hydroxyurea in spinal muscular atrophy cells and patients

(2008) Wen-Chen Liang et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Dose comparison trial of sustained-release fampridine in multiple sclerosis

(2008) A. D. Goodman et al.   NEUROLOGY