Altered lipid metabolism in a Drosophila model of Friedreich's ataxia

Phospholipase A2, reactive oxygen species, and lipid peroxidation in CNS pathologies

(2011) Rao Muralikrishna Adibhatla et al.   BMB Reports

Human apolipoprotein D overexpression in transgenic mice induces insulin resistance and alters lipid metabolism

(2009) Sonia Do Carmo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Hyperoxia-induced neurodegeneration as a tool to identify neuroprotective genes in Drosophila melanogaster

(2009) Christoph Gruenewald et al.   FREE RADICAL BIOLOGY AND MEDICINE

Functional genomic analysis of frataxin deficiency reveals tissue-specific alterations and identifies the PPARγ pathway as a therapeutic target in Friedreich’s ataxia

(2009) Giovanni Coppola et al.   HUMAN MOLECULAR GENETICS

Maintaining the brain: insight into human neurodegeneration from Drosophila melanogaster mutants

(2009) Derek Lessing et al.   NATURE REVIEWS GENETICS

Bacterial frataxin CyaY is the gatekeeper of iron-sulfur cluster formation catalyzed by IscS

(2009) Salvatore Adinolfi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Apolipoprotein D modulates F2-isoprostane and 7-ketocholesterol formation and has a neuroprotective effect on organotypic hippocampal cultures after kainate-induced excitotoxic injury

(2009) Xin He et al.   NEUROSCIENCE LETTERS

Impaired Nuclear Nrf2 Translocation Undermines the Oxidative Stress Response in Friedreich Ataxia

(2009) Vincent Paupe et al.   PLoS One

Control of Metabolic Homeostasis by Stress Signaling Is Mediated by the Lipocalin NLaz

(2009) Julie Hull-Thompson et al.   PLoS Genetics

Apolipoprotein D is involved in the mechanisms regulating protection from oxidative stress

(2008) Maria D. Ganfornina et al.   AGING CELL

Cell functions impaired by frataxin deficiency are restored by drug-mediated iron relocation

(2008) O. Kakhlon et al.   BLOOD

The plant Apolipoprotein D ortholog protects Arabidopsis against oxidative stress

(2008) Jean-Benoit F Charron et al.   BMC PLANT BIOLOGY

PPAR-γ Agonist Azelaoyl PAF Increases Frataxin Protein and mRNA Expression. New Implications for the Friedreich’s Ataxia Therapy

(2008) Daniele Marmolino et al.   CEREBELLUM

Overexpression of frataxin in the mitochondria increases resistance to oxidative stress and extends lifespan inDrosophila

(2008) Alexander P. Runko et al.   FEBS LETTERS

Major targets of iron-induced protein oxidative damage in frataxin-deficient yeasts are magnesium-binding proteins

(2008) Verónica Irazusta et al.   FREE RADICAL BIOLOGY AND MEDICINE

Molecular interactions of the neuronal GPI-anchored lipocalin Lazarillo

(2008) Diego Sanchez et al.   JOURNAL OF MOLECULAR RECOGNITION

Neuroprotective Effect of Apolipoprotein D against Human Coronavirus OC43-Induced Encephalitis in Mice

(2008) S. Do Carmo et al.   JOURNAL OF NEUROSCIENCE

Human ApoD, an apolipoprotein up-regulated in neurodegenerative diseases, extends lifespan and increases stress resistance in Drosophila

(2008) J. Muffat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen peroxide scavenging rescues frataxin deficiency in a Drosophila model of Friedreich's ataxia

(2008) P. R. Anderson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteomic analysis of hearts from frataxin knockout mice: Marked rearrangement of energy metabolism, a response to cellular stress and altered expression of proteins involved in cell structure, motility and metabolism

(2008) Robert Sutak et al.   PROTEOMICS