The early-onset torsion dystonia-associated protein, torsinA, is a homeostatic regulator of endoplasmic reticulum stress response

The early-onset torsion dystonia-associated protein, torsinA, displays molecular chaperone activity in vitro

(2010) Alexander J. Burdette et al.   CELL STRESS & CHAPERONES

Chemical enhancement of torsinA function in cell and animal models of torsion dystonia

(2010) S. Cao et al.   Disease Models & Mechanisms

Protein Homeostasis and Aging: Taking Care of Proteins From the Cradle to the Grave

(2009) R. I. Morimoto et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

LULL1 Retargets TorsinA to the Nuclear Envelope Revealing an Activity That Is Impaired by the DYT1 Dystonia Mutation

(2009) Abigail B. Vander Heyden et al.   MOLECULAR BIOLOGY OF THE CELL

A role for motoneuron subtype–selective ER stress in disease manifestations of FALS mice

(2009) Smita Saxena et al.   NATURE NEUROSCIENCE

Endoplasmic Reticulum Stress in Disease Pathogenesis

(2008) Jonathan H. Lin et al.   Annual Review of Pathology-Mechanisms of Disease

Reduced Translocation of Nascent Prion Protein During ER Stress Contributes to Neurodegeneration

(2008) Neena S. Rane et al.   DEVELOPMENTAL CELL

Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging

(2008) R. I. Morimoto   GENES & DEVELOPMENT

siRNA knock-down of mutant torsinA restores processing through secretory pathway in DYT1 dystonia cells

(2008) J. W. Hewett et al.   HUMAN MOLECULAR GENETICS

Dystonia-associated mutations cause premature degradation of torsinA protein and cell-type-specific mislocalization to the nuclear envelope

(2008) L. M. Giles et al.   HUMAN MOLECULAR GENETICS

The pathophysiological basis of dystonias

(2008) Xandra O. Breakefield et al.   NATURE REVIEWS NEUROSCIENCE

Consequences of the DYT1 mutation on torsinA oligomerization and degradation

(2008) K.L. Gordon et al.   NEUROSCIENCE

Hypothesis-based RNAi screening identifies neuroprotective genes in a Parkinson's disease model

(2008) S. Hamamichi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adapting Proteostasis for Disease Intervention

(2008) William E. Balch et al.   SCIENCE

Activation of the Unfolded Protein Response Is Required for Defenses against Bacterial Pore-Forming Toxin In Vivo

(2008) Larry J. Bischof et al.   PLoS Pathogens