Loss of cone photoreceptors caused by chromophore depletion is partially prevented by the artificial chromophore pro-drug, 9-cis-retinyl acetate

In conditions of limited chromophore supply rods entrap 11-cis-retinal leading to loss of cone function and cell death

(2009) M. Samardzija et al.   HUMAN MOLECULAR GENETICS

Metabolic Basis of Visual Cycle Inhibition by Retinoid and Nonretinoid Compounds in the Vertebrate Retina

(2008) Marcin Golczak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Trafficking of Membrane-Associated Proteins to Cone Photoreceptor Outer Segments Requires the Chromophore 11-cis-Retinal

(2008) H. Zhang et al.   JOURNAL OF NEUROSCIENCE

Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis

(2008) Albert M. Maguire et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effect of Gene Therapy on Visual Function in Leber's Congenital Amaurosis

(2008) James W.B. Bainbridge et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ultrahigh resolution optical coherence tomography and pancorrection for cellular imaging of the living human retina

(2008) Enrique J. Fernández et al.   OPTICS EXPRESS

Ultrahigh speed Spectral / Fourier domain OCT ophthalmic imaging at 70,000 to 312,500 axial scans per second

(2008) Benjamin Potsaid et al.   OPTICS EXPRESS

Retinal pigment epithelium segmentation by polarization sensitive optical coherence tomography

(2008) Erich Götzinger et al.   OPTICS EXPRESS

Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics

(2008) A. V. Cideciyan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Leber congenital amaurosis: Genes, proteins and disease mechanisms

(2008) Anneke I. den Hollander et al.   PROGRESS IN RETINAL AND EYE RESEARCH