Candidate locus analysis of the TERT–CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk

Hypomethylation of the CTCFL/BORIS promoter and aberrant expression during endometrial cancer progression suggests a role as an Epi-driver gene

(2015) Erling A. Hoivik et al.   Oncotarget

Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk

(2014) Jodie N. Painter et al.   HUMAN MOLECULAR GENETICS

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33

(2014) Z. Wang et al.   HUMAN MOLECULAR GENETICS

Microarray Analysis Reveals Distinct Gene Expression Profiles Among Different Tumor Histology, Stage and Disease Outcomes in Endometrial Adenocarcinoma

(2014) Paulette Mhawech-Fauceglia et al.   PLoS One

CRR9/CLPTM1L Regulates Cell Survival Signaling and Is Required for Ras Transformation and Lung Tumorigenesis

(2013) M. A. James et al.   CANCER RESEARCH

Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression

(2013) Zsofia Kote-Jarai et al.   HUMAN MOLECULAR GENETICS

High Frequency Strand Slippage Mutations inCTCFin MSI-Positive Endometrial Cancers

(2013) Israel Zighelboim et al.   HUMAN MUTATION

Germline and somatic polymerase ϵ and δ mutations define a new class of hypermutated colorectal and endometrial cancers

(2013) Sarah Briggs et al.   JOURNAL OF PATHOLOGY

Integrated genomic characterization of endometrial carcinoma

(2013) Gad Getz et al.   NATURE

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

(2013) Paul D P Pharoah et al.   NATURE GENETICS

Turning of COGS moves forward findings for hormonally mediated cancers

(2013) Lori C Sakoda et al.   NATURE GENETICS

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

(2013) Stig E Bojesen et al.   NATURE GENETICS

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

(2013) Kyriaki Michailidou et al.   NATURE GENETICS

Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer

(2013) Hui Shen et al.   Nature Communications

Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk

(2013) Fergus J. Couch et al.   PLoS Genetics

Annotation of functional variation in personal genomes using RegulomeDB

(2012) A. P. Boyle et al.   GENOME RESEARCH

Thyroid cancer susceptibility polymorphisms: confirmation of loci on chromosomes 9q22 and 14q13, validation of a recessive 8q24 locus and failure to replicate a locus on 5q24

(2012) Angela M Jones et al.   JOURNAL OF MEDICAL GENETICS

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

(2012) Claire Palles et al.   NATURE GENETICS

HNF1B and Endometrial Cancer Risk: Results from the PAGE study

(2012) Veronica Wendy Setiawan et al.   PLoS One

Using Penalised Logistic Regression to Fine Map HLA Variants for Rheumatoid Arthritis

(2011) Charlotte M. Vignal et al.   ANNALS OF HUMAN GENETICS

Identifier mapping performance for integrating transcriptomics and proteomics experimental results

(2011) Roger S Day et al.   BMC BIOINFORMATICS

Fine-mapping of colorectal cancer susceptibility loci at 8q23.3, 16q22.1 and 19q13.11: refinement of association signals and use of in silico analysis to suggest functional variation and unexpected candidate target genes

(2011) Luis G. Carvajal-Carmona et al.   HUMAN MOLECULAR GENETICS

A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor–negative breast cancer

(2011) Christopher A Haiman et al.   NATURE GENETICS

Genome-wide association study identifies a common variant associated with risk of endometrial cancer

(2011) Amanda B Spurdle et al.   NATURE GENETICS

Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study

(2011) Zsofia Kote-Jarai et al.   NATURE GENETICS

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

Telomere length and genetic analyses in population-based studies of endometrial cancer risk

(2010) Jennifer Prescott et al.   CANCER

Multiple Genetic Variants in Telomere Pathway Genes and Breast Cancer Risk

(2010) J. Shen et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33

(2010) Gloria M Petersen et al.   NATURE GENETICS

Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer

(2010) Clare Turnbull et al.   NATURE GENETICS

Genotype imputation for genome-wide association studies

(2010) Jonathan Marchini et al.   NATURE REVIEWS GENETICS

A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma

(2009) Maria Teresa Landi et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Two Estrogen-Related Variants in CYP19A1 and Endometrial Cancer Risk: A Pooled Analysis in the Epidemiology of Endometrial Cancer Consortium

(2009) V. W. Setiawan et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

New common variants affecting susceptibility to basal cell carcinoma

(2009) Simon N Stacey et al.   NATURE GENETICS

Sequence variants at the TERT-CLPTM1L locus associate with many cancer types

(2009) Thorunn Rafnar et al.   NATURE GENETICS

Genome-wide association study identifies five susceptibility loci for glioma

(2009) Sanjay Shete et al.   NATURE GENETICS

Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation

(2009) H. B. Salvesen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

Common 5p15.33 and 6p21.33 variants influence lung cancer risk

(2008) Yufei Wang et al.   NATURE GENETICS

Multiple loci identified in a genome-wide association study of prostate cancer

(2008) Gilles Thomas et al.   NATURE GENETICS

Lung cancer susceptibility locus at 5p15.33

(2008) James D McKay et al.   NATURE GENETICS

Simultaneous Analysis of All SNPs in Genome-Wide and Re-Sequencing Association Studies

(2008) Clive J. Hoggart et al.   PLoS Genetics