High Efficiency Restriction Enzyme–Free Linear Amplification-Mediated Polymerase Chain Reaction Approach for Tracking Lentiviral Integration Sites Does Not Abrogate Retrieval Bias

A genome-wide analysis of lentivector integration sites using targeted sequence capture and next generation sequencing technology

(2012) Duran Ustek et al.   INFECTION GENETICS AND EVOLUTION

Hematopoietic stem cell engineering at a crossroads

(2011) I. Riviere et al.   BLOOD

You Can Count on This: Barcoded Hematopoietic Stem Cells

(2011) Hanno Glimm et al.   Cell Stem Cell

Genotoxicity of retroviral hematopoietic stem cell gene therapy

(2011) Grant D Trobridge   EXPERT OPINION ON BIOLOGICAL THERAPY

Lentiviral Vectors: Their Molecular Design, Safety, and Use in Laboratory and Preclinical Research

(2011) Boro Dropulić   HUMAN GENE THERAPY

Tracking single hematopoietic stem cells in vivo using high-throughput sequencing in conjunction with viral genetic barcoding

(2011) Rong Lu et al.   NATURE BIOTECHNOLOGY

A method to sequence and quantify DNA integration for monitoring outcome in gene therapy

(2011) Troy Brady et al.   NUCLEIC ACIDS RESEARCH

Stem cell gene therapy: the risks of insertional mutagenesis and approaches to minimize genotoxicity

(2011) Chuanfeng Wu et al.   Frontiers of Medicine

Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells

(2010) Eirini P Papapetrou et al.   NATURE BIOTECHNOLOGY

Genome-wide high-throughput integrome analyses by nrLAM-PCR and next-generation sequencing

(2010) Anna Paruzynski et al.   Nature Protocols

Efficacy of Gene Therapy for X-Linked Severe Combined Immunodeficiency

(2010) Salima Hacein-Bey-Abina et al.   NEW ENGLAND JOURNAL OF MEDICINE

Stem-Cell Gene Therapy for the Wiskott–Aldrich Syndrome

(2010) Kaan Boztug et al.   NEW ENGLAND JOURNAL OF MEDICINE

Retrovirus gene therapy for X-linked chronic granulomatous disease can achieve stable long-term correction of oxidase activity in peripheral blood neutrophils

(2009) E. M. Kang et al.   BLOOD

Comprehensive genomic access to vector integration in clinical gene therapy

(2009) Richard Gabriel et al.   NATURE MEDICINE

Hematopoietic Stem Cell Gene Therapy with a Lentiviral Vector in X-Linked Adrenoleukodystrophy

(2009) N. Cartier et al.   SCIENCE

Flanking-sequence exponential anchored–polymerase chain reaction amplification: a sensitive and highly specific method for detecting retroviral integrant–host–junction sequences

(2008) M.A. Pule et al.   CYTOTHERAPY

Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients

(2008) Steven J. Howe et al.   JOURNAL OF CLINICAL INVESTIGATION