Enhanced Function of Redirected Human T Cells Expressing Linker for Activation of T Cells That Is Resistant to Ubiquitylation

Treatment of Advanced Leukemia in Mice with mRNA Engineered T Cells

(2011) David M. Barrett et al.   HUMAN GENE THERAPY

Functional Nanoscale Organization of Signaling Molecules Downstream of the T Cell Antigen Receptor

(2011) Eilon Sherman et al.   IMMUNITY

CARs on Track in the Clinic

(2011) Donald B Kohn et al.   MOLECULAR THERAPY

Enhanced T-cell signaling in cells bearing linker for activation of T-cell (LAT) molecules resistant to ubiquitylation

(2011) L. Balagopalan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T Cells with Chimeric Antigen Receptors Have Potent Antitumor Effects and Can Establish Memory in Patients with Advanced Leukemia

(2011) M. Kalos et al.   Science Translational Medicine

Genetic Modification of T Cells

(2010) Chiara Bonini et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Improved Clinical Outcome in Indolent B-Cell Lymphoma Patients Vaccinated with Autologous Tumor Cells Experiencing Immunogenic Death

(2010) R. Zappasodi et al.   CANCER RESEARCH

Development and application of a multiplexable flow cytometry-based assay to quantify cell-mediated cytolysis

(2010) Lan-Feng Cao et al.   CYTOMETRY PART A

An improved technique for calculating relative response in cellular proliferation experiments

(2010) Mark E. Munson   CYTOMETRY PART A

The Importance of LAT in the Activation, Homeostasis, and Regulatory Function of T Cells

(2010) Shudan Shen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decreased Diacylglycerol Metabolism Enhances ERK Activation and Augments CD8+T Cell Functional Responses

(2010) Matthew J. Riese et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dendritic cells control T cell tonic signaling required for responsiveness to foreign antigen

(2010) K. Hochweller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Inducible Costimulator (ICOS) Is Critical for the Development of Human TH17 Cells

(2010) C. M. Paulos et al.   Science Translational Medicine

The TCR-mediated signaling pathways that control the direction of helper T cell differentiation

(2010) Toshinori Nakayama et al.   SEMINARS IN IMMUNOLOGY

Lymphoproliferative disorders involving T helper effector cells with defective LAT signalosomes

(2010) Romain Roncagalli et al.   Seminars in Immunopathology

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

(2009) L. A. Johnson et al.   BLOOD

Loss of the LAT Adaptor Converts Antigen-Responsive T Cells into Pathogenic Effectors that Function Independently of the T Cell Receptor

(2009) Michael Mingueneau et al.   IMMUNITY

Chimeric Receptors Containing CD137 Signal Transduction Domains Mediate Enhanced Survival of T Cells and Increased Antileukemic Efficacy In Vivo

(2009) Michael C. Milone et al.   MOLECULAR THERAPY

Detection of sequential polyubiquitylation on a millisecond timescale

(2009) Nathan W. Pierce et al.   NATURE

Complete but curtailed T-cell response to very low-affinity antigen

(2009) Dietmar Zehn et al.   NATURE

TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation

(2009) Björn F Lillemeier et al.   NATURE IMMUNOLOGY

Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains

(2009) C. Carpenito et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of lymphocyte development and activation by negative regulatory transmembrane adapter proteins

(2008) Luca Simeoni et al.   IMMUNOLOGICAL REVIEWS