Efficient Melanoma Cell Killing and Reduced Melanoma Growth in Mice by a Selective Replicating Adenovirus Armed with Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand

Phase II trial of mapatumumab, a fully human agonistic monoclonal antibody that targets and activates the tumour necrosis factor apoptosis-inducing ligand receptor-1 (TRAIL-R1), in patients with refractory colorectal cancer

(2010) T Trarbach et al.   BRITISH JOURNAL OF CANCER

Effect of Administration Route on the Biodistribution and Shedding of Replication-Deficient HAdV-5: A Qualitative Modelling Approach

(2010) Birgitte Tiesjema et al.   CURRENT GENE THERAPY

Increased expression of MAP2 inhibits melanoma cell proliferation, invasion and tumor growth in vitro and in vivo

(2010) Zhiqi Song et al.   EXPERIMENTAL DERMATOLOGY

Review: On TRAIL for malignant glioma therapy?

(2010) J. M. A. Kuijlen et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Is TRAIL the holy grail of cancer therapy?

(2009) Thomas Newsom-Davis et al.   APOPTOSIS

Antitumor activity of Ad-IU2, a prostate-specific replication-competent adenovirus encoding the apoptosis inducer, TRAIL

(2009) J A Jiménez et al.   CANCER GENE THERAPY

Conditionally replicating adenovirus improves gene replication efficiency and anticancer effect of E1-deleted adenovirus carrying TRAIL in head and neck squamous cell carcinoma

(2009) Seon-Hui Shim et al.   CANCER SCIENCE

Efficient and selective tumor cell lysis and induction of apoptosis in melanoma cells by a conditional replication-competent CD95L adenovirus

(2009) Lothar F. Fecker et al.   EXPERIMENTAL DERMATOLOGY

Potent Antitumor Effect of Interleukin-24 Gene in the Survivin Promoter and Retinoblastoma Double-Regulated Oncolytic Adenovirus

(2009) Kang Jian Zhang et al.   HUMAN GENE THERAPY

Results of a Phase III, Randomized, Placebo-Controlled Study of Sorafenib in Combination With Carboplatin and Paclitaxel As Second-Line Treatment in Patients With Unresectable Stage III or Stage IV Melanoma

(2009) Axel Hauschild et al.   JOURNAL OF CLINICAL ONCOLOGY

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and paclitaxel have cooperative in vivo effects against glioblastoma multiforme cells

(2009) J. F. Dorsey et al.   MOLECULAR CANCER THERAPEUTICS

A Phase 1 Study of Mapatumumab (Fully Human Monoclonal Antibody to TRAIL-R1) in Patients with Advanced Solid Malignancies

(2008) S. J. Hotte et al.   CLINICAL CANCER RESEARCH

Expression and Function of Bcl-2 Proteins in Melanoma

(2008) Jurgen Eberle et al.   CURRENT GENOMICS

Intralesional Adenovirus-mediated Interleukin-2 Gene Transfer for Advanced Solid Cancers and Melanoma

(2008) Reinhard Dummer et al.   MOLECULAR THERAPY