Benzo(a)pyrene-7,8-diol-9,10-epoxide induced p53-independent necrosis via the mitochondria-associated pathway involving Bax and Bak activation

The p53 protein and its molecular network: Modelling a missing link between DNA damage and cell fate

(2013) Ján Eliaš et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Emodin induces apoptosis of human cervical cancer hela cells via intrinsic mitochondrial and extrinsic death receptor pathway

(2013) Wang Yaoxian et al.   Cancer Cell International

DNA damage signaling assessed in individual cells in relation to the cell cycle phase and induction of apoptosis

(2012) Zbigniew Darzynkiewicz et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Apoptosis and necrosis: two different outcomes of cigarette smoke condensate-induced endothelial cell death

(2012) B Messner et al.   Cell Death & Disease

Targeting p53 to mitochondria for cancer therapy

(2011) Lorenzo Galluzzi et al.   CELL CYCLE

Benzo(a)pyrene-induced mitochondrial dysfunction and cell death in p53-null Hep3B cells

(2011) Ying Jiang et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Methoxychlor induces apoptosis via mitochondria- and FasL-mediated pathways in adult rat testis

(2010) S. Vaithinathan et al.   CHEMICO-BIOLOGICAL INTERACTIONS

AIF promotes chromatinolysis and caspase-independent programmed necrosis by interacting with histone H2AX

(2010) Cédric Artus et al.   EMBO JOURNAL

Benzo(a)pyrene induces p73 mRNA expression and necrosis in human lung adenocarcinoma H1299 cells

(2010) Ying Jiang et al.   ENVIRONMENTAL TOXICOLOGY

Mutagenic activation and detoxification of benzo[a]pyrene in vitro by hepatic cytochrome P450 1A1 and phase II enzymes in three meat-producing animals

(2010) W. Darwish et al.   FOOD AND CHEMICAL TOXICOLOGY

Both p53–PUMA/NOXA–Bax-mitochondrion and p53–p21cip1 pathways are involved in the CDglyTK-mediated tumor cell suppression

(2009) Zhendong Yu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members

(2009) Tristan Gallenne et al.   JOURNAL OF CELL BIOLOGY

Essential Role for DNA-PKcs in DNA Double-Strand Break Repair and Apoptosis in ATM-Deficient Lymphocytes

(2009) Elsa Callén et al.   MOLECULAR CELL

Synergistic damage by UVA radiation and pollutants

(2009) KE Burke et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Posttranslational Modification of p53: Cooperative Integrators of Function

(2009) D. W. Meek et al.   Cold Spring Harbor Perspectives in Biology

Role of p53, PUMA, and Bax in wogonin-induced apoptosis in human cancer cells

(2008) Dae-Hee Lee et al.   BIOCHEMICAL PHARMACOLOGY

Catechin, green tea component, causes caspase-independent necrosis-like cell death in chronic myelogenous leukemia

(2008) Reo Iwasaki et al.   CANCER SCIENCE

Oxygen Radical Induced Gastric Mucosal Cell Death: Apoptosis or Necrosis?

(2008) Anna M. Leung et al.   DIGESTIVE DISEASES AND SCIENCES

Key role for Bak activation and Bak-Bax interaction in the apoptotic response to vinblastine

(2008) M. Upreti et al.   MOLECULAR CANCER THERAPEUTICS

Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax

(2008) J. I. Fletcher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Benzo[a]pyrene-induced necrosis in the HepG2 cells via PARP-1 activation and NAD+ depletion

(2008) T. Lin et al.   TOXICOLOGY

MAPK regulate p53-dependent cell death induced by benzo[a]pyrene: Involvement of p53 phosphorylation and acetylation

(2008) T. Lin et al.   TOXICOLOGY