Journal
HORMONES-INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM
Volume 13, Issue 3, Pages 314-322Publisher
SPRINGER INTERNATIONAL PUBLISHING AG
DOI: 10.14310/horm.2002.1505
Keywords
Abortion; Hyperprolactinaemia; Luteal phase defect; Miscarriage; Recurrent pregnancy loss
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Endocrine disorders play a major role in approximately 8% to 12% of recurrent pregnancy loss (RPL). Indeed, the local hormonal milieu is crucial in both embryo attachment and early pregnancy. Endocrine abnormalities, including thyroid disorders, luteal phase defects, polycystic ovary syndrome, hyperprolactinaemia and diabetes have to be evaluated in any case of RPL. Moreover, elevated androgen levels and some endocrinological aspects of endometriosis are also factors contributing to RPL. In the present article, we review the significance of endocrine disease on RPL.
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