Article
Biochemistry & Molecular Biology
Olawande C. Olagoke, Ana L. A. Segatto, Blessing A. Afolabi, Joao B. T. Rocha
Summary: The study validates Nauphoeta cinerea as an experimental organism for studying STZ-induced metabolic disruptions, and finds that STZ treatment leads to changes in the expression of inflammation and antioxidant genes.
CHEMICO-BIOLOGICAL INTERACTIONS
(2021)
Article
Behavioral Sciences
Hsiang-Wen Hsieh, Shu-Chun Chen, Wan-Chen Huang, Shu Fang, En-Cheng Yang, Chu-Chun Hsu, Rong Kou
Summary: The study reveals an increase in tryptophan and tyrosine levels in the hemolymph of male Nauphoeta cinerea after social contact, with different responses in dominants and subordinates. Additionally, different outcomes were observed after male-female interactions, with varying levels of amino acids and behaviors observed. The results suggest a multi-dimensional physiological response to social contact in N. cinerea, alongside previously characterized responses in pheromone and juvenile hormone levels.
HORMONES AND BEHAVIOR
(2021)
Article
Parasitology
Carlos Vinicius Barros Oliveira, Daniel Honorato Neves, Elayne Eally de Souza Morais, Thalyta Julyanne Silva de Oliveira, Mayara Maria da Silva, Luiz Marivando Barros, Antonia Eliene Duarte
Summary: This study identified and characterized the distribution of protozoa in the digestive system of the lobster cockroach Nauphoeta cinerea. The findings reveal the presence of diverse protozoa and potential human pathogens in this system. Further molecular and genetic testing is needed to understand the interactions between these endocommensal protozoa and their invertebrate hosts.
ACTA PARASITOLOGICA
(2022)
Article
Environmental Sciences
Isaac A. Adedara, Umin-Awaji S. Godswill, Miriam A. Mike, Blessing A. Afolabi, Chizoba C. Amorha, Joseph Sule, Joao B. T. Rocha, Ebenezer O. Farombi
Summary: The global detection of ciprofloxacin and atrazine in soil is related to intensive agricultural activities and industrial waste discharge. Nauphoeta cinerea, a terrestrial insect, showed neurobehavioral and cellular responses when exposed singly and jointly to atrazine and ciprofloxacin. Exposure to binary mixtures of these chemicals led to greater locomotor and exploratory deficits in the insects compared to exposure to individual compounds, highlighting the need for further research on the ecological risks of contaminants.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Cell Biology
Olawande C. Olagoke, Blessing A. Afolabi, Joao B. T. Rocha
Summary: Developing new models to study diabetes in invertebrates is crucial for adhering to the 3R's principle and advancing our understanding of the complex molecular mechanisms involved in glucose toxicity. The use of Streptozotocin (STZ) as a model for type 1 diabetes in rodents is well-known, but its effects in insects, such as cockroaches, are less understood. By injecting different doses of STZ into cockroaches, researchers observed disruptions in glucose utilization in the insect's head and fat body, leading to changes in glucose content, survival rates, oxidative stress levels, and other markers. Additionally, increased levels of glutathione-related activities suggest a compensatory response to the rise in reactive oxygen species, highlighting potential metabolic disturbances in cockroaches exposed to glucose analogues.
MOLECULAR AND CELLULAR BIOCHEMISTRY
(2021)
Article
Environmental Sciences
Isaac A. Adedara, Oluwatoyin O. Abioye, Gbemisola T. Oyedele, Cynthia N. Ikeji, Blessing A. Afolabi, Joao B. T. Rocha, Ebenezer O. Farombi
Summary: This study evaluated the toxicological impact of PFOA on Nauphoeta cinerea insects. The results showed that PFOA exposure led to reduced locomotory abilities and increased freezing time in the insects, along with changes in several biochemical markers. This indicates that PFOA poses an ecological risk to Nauphoeta cinerea.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Environmental Sciences
Gbemisola T. Oyedele, Isaac A. Adedara, Cynthia N. Ikeji, Blessing A. Afolabi, Joao B. T. Rocha, Ebenezer O. Farombi
Summary: Metoprolol, a drug used for hypertension and cardiovascular diseases, has been detected globally in various environmental matrices and is a emerging contaminant of concern. This study evaluated the toxicological impact of environmentally relevant concentrations of metoprolol on Nauphoeta cinerea nymphs. The results showed that metoprolol exposure reduced the insects' behavior and induced oxidative and inflammatory injury in their bodies. These findings suggest that metoprolol contamination may have potential health effects on non-target insects.
ENVIRONMENTAL TOXICOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Pedro Silvino Pereira, Adrielle Rodrigues Costa, Thalyta Julyanne Silva de Oliveira, Carlos Vinicius Barros Oliveira, Maria do Carmo Alves de Lima, Jamerson Ferreira de Oliveira, Bonglee Kim, Henrique D. M. Coutinho, Antonia Eliene Duarte, Jean Paul Kamdem, Teresinha Goncalves da Silva
Summary: Thiazolidine compounds NJ20 and NW05 potentiated the effect of norfloxacin in resistant bacteria, showing moderate neurotoxicity and good antioxidant action in the model organism tested. NW05 did not show toxicity or significant antioxidant activity. Further complementary tests related to antioxidant prospecting of these compounds at different concentrations are desirable.
Article
Environmental Sciences
Isaac A. Adedara, Babajide O. Ajayi, Blessing A. Afolabi, Ifeoluwa O. Awogbindin, Joao B. T. Rocha, Ebenezer O. Farombi
Summary: The study found that exposure to carbamazepine (CBZ) and diazepam (DZP) binary mixtures caused a decrease in behavior and antioxidant status in Nauphoeta cinerea, indicating the potential neurotoxicity through induction of inflammation and oxidative stress.
Article
Multidisciplinary Sciences
Yukako Inoue, Robert P. Burriss, Toshikazu Hasegawa, Toko Kiyonari
Summary: Although testosterone is generally believed to promote dominance behaviors, its relationship with achieving and maintaining social status in humans is ambiguous. Inoue et al.'s study found that high status modulates the dominance behaviors induced by testosterone. Our study, conducted in a university rugby team, showed that individuals with higher baseline salivary testosterone levels exhibited more dominance as their position in the hierarchy increased.
SCIENTIFIC REPORTS
(2023)
Article
Biochemistry & Molecular Biology
Matej Milacek, Lenka Bittova, Sarka Tumova, Ondrej Luksan, Robert Hanus, Pavlina Kyjakova, Ales Machara, Ales Marek, Marek Jindra
Summary: Juvenile hormone controls insect reproduction and development through a receptor complex consisting of Met and Tai proteins, affecting vitellogenesis in cockroaches and caste polyphenism in termites. Studies show high-affinity binding of JH III by Met proteins in cockroaches and termites, with evidence of JH receptor agonist binding in hemimetabolous species.
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
(2021)
Article
Environmental Sciences
Adesina A. Babalola, Khadija A. Mohammed, Adeboye A. Olaseni, Gbemisola T. Oyedele, Isaac A. Adedara, Joao B. T. Rocha, Ebenezer O. Farombi
Summary: This study aimed to investigate the reversibility of the toxicity of perfluorooctanoic acid (PFOA) in adult male and female Nauphoeta cinerea. Both sexes were exposed to different concentrations of PFOA in drinking water for 21 days. The results showed that PFOA exposure led to deficits in locomotor and exploratory capabilities and increased anxiety behaviors in Nauphoeta cinerea, which persisted even after cessation of exposure. PFOA also caused a decrease in acetylcholinesterase activity and increased oxidative stress in the insects, although some of the effects were reversed after cessation of exposure. However, lipid peroxidation and protein carbonyl levels remained elevated in both sexes. Overall, this study demonstrated that PFOA exposure resulted in persistent neurobehavioral and oxidative injuries in adult Nauphoeta cinerea.
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
(2023)
Article
Biology
Zhaoxin Li, Caisheng Zhou, Yumei Chen, Wentao Ma, Yunlong Cheng, Jinxin Chen, Yu Bai, Wei Luo, Na Li, Erxia Du, Sheng Li
Summary: This study identifies the epidermal growth factor receptor (Egfr) as a crucial factor in promoting juvenile hormone (JH) biosynthesis in adult female German cockroaches. The study reveals the detailed molecular mechanism of Egfr signaling and its involvement in regulating JH biosynthesis. This provides new insights into the intricate regulation of JH biosynthesis during insect development.
Article
Fisheries
Michael J. Landman, Basseer M. Codabaccus, Chris G. Carter, Quinn P. Fitzgibbon, Gregory G. Smith
Summary: This study found that dietary PC content had no significant effects on survival, growth, chemical composition, and lipid distribution in juvenile slipper lobsters, indicating that slipper lobsters have efficient mechanisms for lipid digestion. Furthermore, majority of dietary TL and TAG were utilized for energy and metabolic processes, while PC was more reliant on biosynthesis.
Article
Biochemistry & Molecular Biology
Blessing A. Obafemi, Isaac A. Adedara, Ana L. A. Segatto, Diogo O. Souza, Joao B. T. da Rocha, Olawande C. Olagoke
Summary: In this study, the mechanism of inflammatory response to organometallic cation methylmercury, common cooking seasoning (NaCl and MSG), and their crosstalk with redox signaling were investigated using the lobster cockroach as a model. The activation of Nox/Duox NADPH oxidases, along with JNK and Rel signaling pathways, was found to play crucial roles during methylmercury and MSG exposure.
JOURNAL OF FOOD BIOCHEMISTRY
(2023)
Article
Entomology
Zachary Y. Huang, Stephanie Lin, Kiheung Ahn
Article
Entomology
Zachary Y. Huang, Guowu Bian, Zhiyong Xi, Xianbing Xie
Article
Biology
Elizabeth A. Tibbetts, Michelle L. Fearon, Ellery Wong, Zachary Y. Huang, Robin M. Tinghitella
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2018)
Article
Multidisciplinary Sciences
Julia D. Fine, Hagai Y. Shpigler, Allyson M. Ray, Nathanael J. Beach, Alison L. Sankey, Amy Cash-Ahmed, Zachary Y. Huang, Ieva Astrauskaite, Ran Chao, Huimin Zhao, Gene E. Robinson
Article
Entomology
Chuang Zhang, Subas Pokhrel, Zhenhong Wu, Xiaoqing Miao, Zachary Y. Huang, Wenchao Yang
Article
Biotechnology & Applied Microbiology
Fang Liu, Tengfei Shi, Lei Qi, Xin Su, Deqian Wang, Jie Dong, Zachary Y. Huang
Article
Food Science & Technology
Wenchao Yang, Chuang Zhang, Charlie Li, Zachary Yong Huang, Xiaoqing Miao
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
(2019)
Article
Multidisciplinary Sciences
Pierre Lau, Vaughn Bryant, James D. Ellis, Zachary Y. Huang, Joseph Sullivan, Daniel R. Schmehl, Ana R. Cabrera, Juliana Rangel
Article
Entomology
Wenfeng Li, Cheng Wang, Zachary Y. Huang, Yanping Chen, Richou Han
Article
Agronomy
Bai-Zhong Zhang, Xu Su, Lan-Fen Xie, Cong-Ai Zhen, Gui-Lei Hu, Kun Jiang, Zachary Y. Huang, Run-Qiang Liu, Yang-Fan Gao, Xi-Ling Chen, Xi-Wu Gao
Editorial Material
Entomology
Bradley N. Metz, Judy Wu-Smart, Michael Simone-Finstrom
Article
Entomology
Fang Liu, Xinjian Xu, Yuan Zhang, Hongxia Zhao, Zachary Y. Huang
Article
Ecology
Muhammad Shoaib Saleem, Zachary Y. Huang, Meghan O. Milbrath
FRONTIERS IN ECOLOGY AND EVOLUTION
(2020)
Article
Entomology
Fang Liu, Lixian Wu, Yuan Zhang, Qiang Li, Liangbin Li, Zachary Y. Huang, Hongxia Zhao
Summary: This study revealed that Mblk-1 expression is significantly higher in the brains of forager bees compared to nurse bees, and inhibition of Mblk-1 can decrease sucrose responsiveness in foragers. These findings suggest that Mblk-1 may regulate the sucrose responsiveness of foragers by targeting AmGR1.
Article
Biodiversity Conservation
Jonathan L. Teichroew, Jianchu Xu, Antje Ahrends, Zachary Y. Huang, Ken Tan, Zhenghua Xie
BIOLOGICAL CONSERVATION
(2017)
Article
Behavioral Sciences
Farrah N. Madison, Verner P. Bingman, Tom Smulders, Christine R. Lattin
Summary: Although research on the avian hippocampus has been limited, it is crucial for understanding its evolution and changes over time. The avian hippocampus plays important roles in spatial cognition as well as regulating anxiety, approach-avoidance behavior, and stress responses. Future research should focus on elucidating the cellular and molecular mechanisms, including endocrinology, to resolve outstanding questions about avian hippocampal function and organization.
HORMONES AND BEHAVIOR
(2024)
Article
Behavioral Sciences
Judith A. H. Smit, Riet Vooijs, Peter Lindenburg, Alexander T. Baugh, Wouter Halfwerk
Summary: This study investigates the effects of urbanization on hormone levels in tungara frogs and found that urban frogs and forest frogs have different endocrine phenotypes. Exposure to urban noise and light pollution led to an increase in testosterone and a decrease in corticosterone in urban frogs, while forest frogs showed no endocrine response to sensory pollutants. These results suggest that urbanization can modulate hormone levels and influence behavior in frogs.
HORMONES AND BEHAVIOR
(2024)
Article
Behavioral Sciences
Hannah D. Fulenwider, Yangmiao Zhang, Andrey E. Ryabinin
Summary: Social hierarchies have significant effects on overall health of individuals in animal groups, particularly the lowest-ranking individuals. Tube test can be used to determine social rank in male and female mice, and the complex interactions between social rank, sex, environment, and testing length influence peptide levels.
HORMONES AND BEHAVIOR
(2024)