Article
Multidisciplinary Sciences
Paul Ritsche, Philipp Wirth, Martino Franchi, Oliver Faude
Summary: This study presents a novel semi-automatic ImageJ script (ACSAuto) for quantifying lower limb muscle ACSA, which shows good reliability compared to manual analysis. The script demonstrates high consistency and small mean bias when compared to manual measurements, potentially reducing time needed for evaluating ultrasound images.
SCIENTIFIC REPORTS
(2021)
Article
Medicine, General & Internal
Hamidullah Salimi, Shoichiro Ohyama, Hidetomi Terai, Yusuke Hori, Shinji Takahashi, Masatoshi Hoshino, Akito Yabu, Hasibullah Habibi, Akio Kobayashi, Tadao Tsujio, Shiro Kotake, Hiroaki Nakamura
Summary: This study found that bioelectrical impedance analysis is a reliable method to assess trunk muscle mass and correlates with traditional quantitative and functional assessments of trunk muscles.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Geriatrics & Gerontology
Peng Gao, Da Gan, Shanshan Li, Qingcong Kang, Xiaoyan Wang, Weifang Zheng, Xiaochen Xu, Xueyin Zhao, Wei He, Joyce Wu, Ying Lu, Ann W. Hsing, Shankuan Zhu
Summary: This study examined the associations between body flexibility and sarcopenia. The results showed that high flexibility was inversely associated with low muscle mass, low muscle strength, and sarcopenia. Furthermore, increasing flexibility was associated with a reduced risk of incident low muscle mass, low muscle strength, and sarcopenia.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2023)
Article
Multidisciplinary Sciences
Hyunghun Moon, Sung-Ki Lee, Won-Moon Kim, Yong-Gon Seo
Summary: The study found that corrective exercise is more effective in improving the condition of patients with thoracic hyperkyphosis, showing better outcomes in increasing muscle strength and endurance, improving the value of Cobb's angle, and increasing the cross-sectional area of deep muscles in the neck.
SCIENTIFIC REPORTS
(2021)
Article
Medicine, General & Internal
Soo Yeon Park, Kyoung Ho Yoon, Sung Hyun Hwang, Taeg Su Ko, Hee Sung Lee
Summary: Weakening muscle strength around the knee makes it more susceptible to aging-related damage. This study found an association between knee flexor muscle strength and its cross-sectional area (CSA), and observed that both flexor muscle strength and CSA decrease with aging.
Article
Nutrition & Dietetics
Maha H. Alhussain, Shaea Alkahtani, Osama Aljuhani, Syed Shahid Habib
Summary: The study found an association between nutrient intake and diagnostic measures of sarcopenia.
Article
Agriculture, Dairy & Animal Science
Luke K. Fuerniss, Bradley J. Johnson
Summary: This study validated a semi-automated workflow that can efficiently and objectively identify the type and measure the size of muscle fibers compared to a manual technique. The semi-automated workflow is six times faster than the manual workflow and yields similar results. This study demonstrates the efficiency and objectivity of the semi-automated workflow in imaging, classifying, and measuring muscle fibers.
JOURNAL OF ANIMAL SCIENCE
(2023)
Article
Clinical Neurology
Xiaoguang Zhao, Siyuan Chen, Nan Liu, Fei Hu, Jiabin Yu
Summary: This study aimed to explore the relationship between handgrip strength and successful aging in older adults. It found a close association between handgrip strength and successful aging, suggesting that older adults with greater handgrip strength can successfully deal with the challenges of aging.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Endocrinology & Metabolism
Jie Cao, Didi Zuo, Tingting Han, Hongxia Liu, Wenwen Liu, Jia Zhang, Yurong Weng, Xian Jin, Zengai Chen, Yaomin Hu
Summary: Skeletal muscle mass plays a crucial role in health and disease. This study found a strong correlation between erector spinae muscle area assessed from chest CT and bioelectrical impedance analysis (BIA), especially in male subjects and obese individuals.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Environmental Sciences
Xiya Qin, Lulu Song, Gaojie Fan, Qing Liu, Mingyang Wu, Jianing Bi, Qing Fang, Zhengce Wan, Yongman Lv, Youjie Wang
Summary: This study aimed to investigate the effect of metal co-exposure on sex-specific handgrip strength. Linear regression, restricted cubic spline (RCS) model, and weighted quantile sum (WQS) regression were used to evaluate the association of single metal as well as metal mixture with handgrip strength. The results showed that several metallic elements were adversely associated with handgrip strength, especially among men, and cadmium (Cd) may contribute most to the conjunct risk.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Medicine, General & Internal
Stefano Borghi, Matteo Bonato, Antonio La Torre, Giuseppe Banfi, Jacopo Antonino Vitale
Summary: This study investigated the association between lower limb strength, muscle mass and composition, and balance ability in elders. The results showed positive correlations between lower limb strength and appendicular muscle mass, as well as negative correlations between knee extensor strength and thigh intermuscular adipose tissue. Dynamic balance ability did not correlate with any morphological variables of the muscle.
Article
Endocrinology & Metabolism
Ningxin Chen, Tingting Han, Hongxia Liu, Jie Cao, Wenwen Liu, Didi Zuo, Ting Zhang, Xiucai Lan, Xian Jin, Yurong Weng, Yaomin Hu
Summary: This study found a correlation between skeletal muscle fat content and hyperuricemia, indicating that a higher skeletal muscle fat index may be associated with a higher risk of hyperuricemia, independent of body mass index.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Chaoran Liu, Pui Yan Wong, Xin Tong, Simon Kwoon-Ho Chow, Vivian Wing-Yin Hung, Wing-Hoi Cheung, Ling Qin, Sheung Wai Law, Ronald Man Yeung Wong
Summary: This study aimed to investigate the roles of fat and muscle in bone structures and the relationship between obesity and sarcopenia in age-related osteoporosis. Data from 400 participants were analyzed to study the correlation between fat, muscle, and bone, and logistic regression analyses were used to explore the risk of osteoporosis. The results showed that low muscle mass and function were harmful to bone health, while obesity had limited protective roles in osteoporosis.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Nutrition & Dietetics
Zhiying Li, Lijie Gao, Xiaoqing Zhong, Guanrui Feng, Fengqiu Huang, Sujian Xia
Summary: This study investigated the relationship between visceral fat area (VFA) and hyperuricemia (HUA) among non-obese adults. The results showed a positive association between VFA and HUA, with a nonlinear dose-response relationship observed in males.
Article
Geriatrics & Gerontology
Zhihan Lai, Yin Yang, Zhengmin (Min) Qian, Michael G. Vaughn, Maya Tabet, Hualiang Lin
Summary: This study suggests that exposure to ambient air pollution might be a risk factor for sarcopenia.
Article
Psychology, Developmental
Heidrun Lioba Wunram, Stefanie Hamacher, Max Oberste, Susanne Neufang, Luisa Belke, Franziska Jaenicke, Christine Graf, Eckhard Schoenau, Stephan Bender, Oliver Fricke
Summary: Recent meta-analyses have shown a moderate effect of physical activity in treating adolescent depression. Positive prior sports experiences and motivational factors, such as beliefs, expectancies, and enjoyment related to physical activity, can increase the effectiveness of exercise therapy in juvenile depression. Motivational placebo-related factors significantly influence the outcomes of exercise treatment, with a neutral mindset being sufficient to benefit more from physical activity.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2022)
Article
Endocrinology & Metabolism
Lenka Petruzelkova, Pavlina Jiranova, Jan Soupal, Milos Kozak, Lukas Plachy, Vit Neuman, Stepanka Pruhova, Barbora Obermannova, Stanislava Kolouskova, Zdenek Sumnik
Summary: This study found that switching from sensor-augmented pump to AndroidAPS resulted in significantly improved glycemic control in preschool and school-aged children with type 1 diabetes, with increased time in range and decreased HbA1c levels.
PEDIATRIC DIABETES
(2021)
Article
Endocrinology & Metabolism
Zdenek Sumnik, Marketa Pavlikova, Renata Pomahacova, Petra Venhacova, Lenka Petruzelkova, Jaroslav Skvor, David Neumann, Jan Vosahlo, Petra Konecna, Jindrich Cizek, Jiri Strnadel, Stepanka Pruhova, Ondrej Cinek
Summary: The study revealed a rapid increase in CGM use in Czechia over three years following general reimbursement. HbA1c was found to be negatively associated with time spent on CGM, with a continuing decrease observed in the >70% category. Reimbursement for CGM likely contributes to the improvement of T1D control at the population level.
PEDIATRIC DIABETES
(2021)
Article
Endocrinology & Metabolism
Johnny Ludvigsson, Zdenek Sumnik, Terezie Pelikanova, Lia Nattero Chavez, Elena Lundberg, Itxaso Rica, Maria A. Martinez-Brocca, Marisol Ruiz de Adana, Jeanette Wahlberg, Anastasia Katsarou, Ragnar Hanas, Cristina Hernandez, Maria Clemente Leon, Ana Gomez-Gila, Marcus Lind, Marta Ferrer Lozano, Theo Sas, Ulf Samuelsson, Stepanka Pruhova, Fabricia Dietrich, Sara Puente Marin, Anders Nordlund, Ulf Hannelius, Rosaura Casas
Summary: Intralymphatic administration of GAD-alum combined with vitamin D supplementation did not meet the primary endpoint in all patients with T1D, but showed greater preservation of C-peptide in patients with the HLA DR3-DQ2 genotype. This treatment was well-tolerated and may be considered a disease-modifying approach for T1D patients with the specific genetic background.
Article
Environmental Sciences
Heidrun Lioba Wunram, Max Oberste, Stefanie Hamacher, Susanne Neufang, Nils Grote, Maya Kristina Krischer, Wilhelm Bloch, Eckhard Schoenau, Stephan Bender, Oliver Fricke
Summary: This study analyzed the influence of exercise on depressive adolescents and found that physical activity could alleviate depression severity partly through immunomodulation. The results also showed that sex and body mass index could impact the levels of pro-inflammatory cytokines and depression severity in adolescents with depression.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Nutrition & Dietetics
Vit Neuman, Lukas Plachy, Stepanka Pruhova, Stanislava Kolouskova, Lenka Petruzelkova, Barbora Obermannova, Jana Vyzralkova, Petra Konecna, Jan Vosahlo, Martina Romanova, Marketa Pavlikova, Zdenek Sumnik
Summary: This study aimed to investigate the frequency of low-carbohydrate diet (LCD) use among children with type 1 diabetes (T1D) and its association with clinical and laboratory data. Results showed that 39% of the children had experience with carbohydrate restriction, with 5.8% currently following the LCD. The LCD group had modestly better disease control but also showed a tendency toward more frequent hypoglycemia.
Article
Psychiatry
Marie-Lene Scheiderer, Lynn Marie Reuter, Katharina Brockmann, Daniela Reis, David Martin, Alfred Langler, Oliver Fricke
Summary: The study aimed to develop a questionnaire on the architecture of child and adolescent psychiatric facilities to investigate the relationship between architectural features and patient recovery parameters. Through extensive literary analysis and expert interviews, the study identified helpful architectural aspects for therapy, forming the basis for the questionnaire's 20 items.
ZEITSCHRIFT FUR KINDER-UND JUGENDPSYCHIATRIE UND PSYCHOTHERAPIE
(2022)
Article
Medicine, General & Internal
Christa K. Raak, Thomas Ostermann, Anna-Li Schoenenberg-Tu, Oliver Fricke, David D. Martin, Sibylle Robens, Wolfram Scharbrodt
Summary: This study aimed to examine gender differences in postoperative pain and pain medication consumption after spinal sequestrectomy. The reanalysis of data showed no significant differences between male and female patients in pain severity, pain perception, and opioid use.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Health Care Sciences & Services
Peter Schmidt, Daniela Reis, Andreas G. Schulte, Oliver Fricke
Summary: German dentists (with key expertise in paediatric dentistry) have limited competence and comfort levels in treating children and adolescents with disabilities and psycho-emotional disorders. It is necessary to include special care dentistry in the core curriculum to improve their ability to provide care for these patients.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Editorial Material
Endocrinology & Metabolism
Tiago Jeronimo dos Santos, Agata Chobot, Claudia Piona, Klemen Dovc, Torben Biester, Katarzyna Anna Gajewska, Carine de Beaufort, Zdenek Sumnik, Lenka Petruzelkova
PEDIATRIC DIABETES
(2022)
Article
Pediatrics
Louisa Thiekoetter, Peter Schmidt, Marie-Lene Scheiderer, Heidrun Wunram, Michael Paulussen, Daniela Reis, Oliver Fricke
Summary: This study investigated the stress response of German pediatricians to child abuse scenarios and found that they perceived more threat and stress in these situations. The study also found that pediatricians had moderate familiarity with child protection laws and guidelines, but faced communication difficulties with parents and welfare services. Suggestions for improvement include more training and guidance, as well as increased communication among colleagues.
Article
Endocrinology & Metabolism
Ledjonani Toni, Lukas Plachy, Petra Dusatkova, Shenali Anne Amaratunga, Lenka Elblova, Zdenek Sumnik, Stanislava Kolouskova, Marta Snajderova, Barbora Obermannova, Stepanka Pruhova, Jan Lebl
Summary: This study aimed to decipher the genetic causes of short stature in children born small for gestational age and found a high diagnostic yield with a central role of the growth plate, as well as contributions from the GH-IGF-1 and thyroid axes, and intracellular regulation and signaling.
HORMONE RESEARCH IN PAEDIATRICS
(2023)
Article
Endocrinology & Metabolism
Zdenek Sumnik, Marketa Pavlikova, Vit Neuman, Lenka Petruzelkova, Petra Konecna, Petra Venhacova, Jaroslav Skvor, Renata Pomahacova, David Neumann, Jan Vosahlo, Jiri Strnadel, Kamila Kocourkova, Barbora Obermannova, Alzbeta Santova, Lukas Plachy, Stepanka Pruhova, Ondrej Cinek
Summary: This study assesses the differences in key parameters of type 1 diabetes control associated with treatment and monitoring modalities, including the newly introduced hybrid closed-loop (HCL) algorithm. The results show that the HCL technology is superior to other treatment modalities in CGM-derived parameters and should be considered as a treatment of choice in all eligible patients.
HORMONE RESEARCH IN PAEDIATRICS
(2023)
Article
Chemistry, Analytical
Anna-Li Schoenenberg-Tu, Dirk Cysarz, Benjamin Petzold, Carl Benjamin Bluemel, Christa Raak, Oliver Fricke, Friedrich Edelhaeuser, Wolfram Scharbrodt
Summary: This study investigated the impact of temporal resolution of intracranial pressure (ICP) signal on pressure time dose (PTD) calculation. The results showed that lower temporal resolutions led to increased PTD, regardless of waveform morphology and frequency of threshold exceedance. Beat-to-beat PTD best reflected the impact of threshold exceedance frequency and waveform morphology. Therefore, PTD calculation should be standardized, and beat-by-beat PTD could serve as an easy-to-grasp indicator for the impact of frequency and waveform morphology of ICP elevations on ICP burden.
Article
Public, Environmental & Occupational Health
Peter Schmidt, Oliver Fricke, Andreas G. Schulte
Summary: The study found that children and adolescents in need of assistance are inadequately cared for in terms of dental care compared to their peers. Therefore, there is an urgent need to intensify dental care and obtain medical information accurately to implement targeted prevention measures.
