Article
Biology
Garrett J. Blair, Changliang Guo, Shiyun Wang, Michael S. Fanselow, Peyman Golshani, Daniel Aharoni, Hugh T. Blair
Summary: This study found that place cells in the hippocampus of rats undergo remapping during the memory of aversive events, indicating that reorganization of hippocampal population codes may play a role in storing memories for aversive events.
Article
Computer Science, Artificial Intelligence
Tristan Baumann, Hanspeter A. Mallot
Summary: The firing fields of hippocampal place cells, known as remapping, change when a rat enters a new compartment in a maze. Remapping cannot be explained solely by path integration and local sensory cues, but requires additional context recognition at gateways between compartments. A model is proposed where place and grid cells follow a joint attractor dynamic, depending on each other's activity and resetting during remapping triggered by passage through a gateway.
Article
Neurosciences
Joshua B. Julian, Christian F. Doeller
Summary: Julian and Doeller demonstrate that modulation of map-like representations in the human hippocampal-entorhinal system predicts contextual memory retrieval during virtual reality navigation, regardless of visual experience. The study shows how hippocampal-entorhinal mechanisms mediate contextual memory in humans and suggest that the hippocampal formation plays a crucial role in spatial behavior under uncertain conditions.
NATURE NEUROSCIENCE
(2021)
Article
Neurosciences
Jake Ormond, Simon A. Serka, Joshua P. Johansen
Summary: The study explores how episodic memories for distinct experiences occurring within familiar environments are encoded in the hippocampal place cell system. They developed a spatial decision-making task in which male rats learned to navigate a multiarm maze. The results suggest that recruitment into replay events may be a mechanism to incorporate new contextual information into a previously formed and stabilized spatial representation.
JOURNAL OF NEUROSCIENCE
(2023)
Article
Biophysics
Fan Mo, Zhaojie Xu, Gucheng Yang, Penghui Fan, Yiding Wang, Botao Lu, Juntao Liu, Mixia Wang, Luyi Jing, Wei Xu, Ming Li, Jin Shan, Yilin Song, Xinxia Cai
Summary: This study utilized a silicon-based motion microelectrode array to record electrophysiological signals of place cells in the hippocampus of mice in motion. The results revealed the mapping relationships between environmental cues and place cells in short-term memory and identified the existence of place-related cells. Furthermore, the study demonstrated the different roles of place cells in CA1, CA3, and DG regions in spatial memory processing during familiarization with new environments.
BIOSENSORS & BIOELECTRONICS
(2022)
Editorial Material
Neurosciences
Juraj Bevandi, Lisa Genzel, H. Freyja Olafsdottir
Summary: Research on hippocampal circuits indicates that the spatial map encodes new information via pre-existing latent place fields.
Article
Neurosciences
John Widloski, David J. Foster
Summary: This study found that flexibility is crucial for hippocampus-dependent memory. The researchers recorded hippocampal replays and found that they could adapt to different spatial and reward contingencies. The replays were flexible in reflecting the learned contingencies in the environment and were distinct from place field responses.
Article
Multidisciplinary Sciences
Can Dong, Antoine D. Madar, Mark E. J. Sheffield
Summary: The study found that CA1 and CA3 play different roles in spatial memory processing. Place fields in CA1 emerge rapidly but tend to shift backwards from trial-to-trial and remap upon re-exposure to the environment a day later, while place fields in CA3 develop gradually and show more stable trial-to-trial and day-to-day dynamics, indicating distinct functional roles in representing space for each subfield.
NATURE COMMUNICATIONS
(2021)
Article
Neurosciences
Devyn E. Smith, Isabelle L. Moore, Nicole M. Long
Summary: This study identifies brain states using scalp EEG from male and female human subjects and shows the extent to which temporal overlap promotes interference and induces retrieval. Greater temporal overlap leads to impaired memory for the past event selectively when the top-down goal is to encode the present event. Additionally, greater temporal overlap leads to automatic retrieval of a past event, independent of top-down goals. These findings provide insight into the role of temporal overlap on interference and memory formation.
JOURNAL OF NEUROSCIENCE
(2022)
Article
Computer Science, Artificial Intelligence
Bingbing Wei, Hongyu Chen, Qinghai Ding, Haibo Luo
Summary: To address the problem of robustly adapting to appearance variations in challenging situations, the proposed online updatable Siamese tracker (SiamSTC) leverages spatiotemporal context to improve accuracy and robustness of tracking. It builds a memory bank to collect spatial and temporal contexts and utilizes a template update module to learn an adaptive target template. The method achieves state-of-the-art tracking performance on various challenging benchmarks.
KNOWLEDGE-BASED SYSTEMS
(2023)
Article
Psychology, Experimental
James E. Kragel, Joel L. Voss
Summary: The study found that memories for episodes have a temporal structure, with individuals being able to reinstate eye movement sequences between different events during complex scene viewing, which weaken over time and are associated with successful memory. Even after considering consistent eye movements produced by inherent scene properties, memory-driven reinstatement still occurs.
JOURNAL OF EXPERIMENTAL PSYCHOLOGY-GENERAL
(2021)
Article
Biology
Isabel I. C. Low, Lisa M. Giocomo, Alex H. Williams
Summary: Researchers found that neurons in navigational brain regions can change their firing patterns in response to changing contextual factors while preserving local computations. By training neural network models to track position and report transiently-cued context changes in simple environments, they showed that the activity patterns are similar to population-wide remapping in the navigational brain region. Furthermore, the models' solution generalizes to more complex navigation and inference tasks.
Review
Biology
Eleonore Duvelle, Roddy M. Grieves, Matthijs A. A. Van der Meer
Summary: The hippocampus is crucial for encoding, organizing, and using structured representations to plan for the future. This review focuses on examining the role of 'splitter cells' in understanding hippocampal function and proposes two major theoretical ideas about temporal context and state inference. The findings support both theories but also highlight the need for further research to refine our understanding of hippocampal function.
Article
Neurosciences
Chuqi Liu, Zhifang Ye, Chuansheng Chen, Nikolai Axmacher, Gui Xue
Summary: The hippocampus is important in representing spatial locations and sequences, but its role in memory for the temporal order of random items is not well understood. This study found that different subfields of the hippocampus contain representations of multiple features of sequence structure and can flexibly transform these representations to support accurate temporal order memory.
Article
Multidisciplinary Sciences
Shota Shimoda, Takaaki Ozawa, Yukio Ichitani, Kazuo Yamada
Summary: The length of the familiarization period has an impact on performance in spontaneous recognition tests, especially in associative recognition memory. Longer familiarization periods are necessary for long-term associative recognition memory than for non-associative memory, while successful discrimination can still be achieved under short and long familiarization periods in place and object recognition tests.
Article
Neurosciences
Geoffrey W. Diehl, Olivia J. Hon, Stefan Leutgeb, Jill K. Leutgeb
Article
Biochemistry & Molecular Biology
Ipshita Zutshi, Mark P. Brandon, Maylin L. Fu, Macayla L. Donegan, Jill K. Leutgeb, Stefan Leutgeb
Article
Neurosciences
Takuya Sasaki, Vernica C. Piattil, Ernie Hwaun, Siavash Ahmadi, John E. Lisman, Stefan Leutgeb, Jill K. Leutgeb
NATURE NEUROSCIENCE
(2018)
Article
Cell Biology
Magdalene I. Schlesiger, Brittney L. Boublil, Jena B. Hales, Jill K. Leutgeb, Stefan Leutgeb
Article
Neurosciences
Honi Sanders, Daoyun Ji, Takuya Sasaki, Jill K. Leutgeb, Matthew A. Wilson, John E. Lisman
Article
Multidisciplinary Sciences
Ipshita Zutshi, Maylin L. Fu, Varoth Lilascharoen, Jill K. Leutgeb, Byung Kook Lim, Stefan Leutgeb
NATURE COMMUNICATIONS
(2018)
Article
Neurosciences
Emily A. Mankin, Kay Thurley, Alireza Chenani, Olivia V. Haas, Luca Debs, Josephine Henke, Melissa Galinato, Jill K. Leutgeb, Stefan Leutgeb, Christian Leibold
Article
Multidisciplinary Sciences
Alireza Chenani, Marta Sabariego, Magdalene Schlesiger, Jill K. Leutgeb, Stefan Leutgeb, Christian Leibold
NATURE COMMUNICATIONS
(2019)
Article
Biochemistry & Molecular Biology
Catherine A. Marcinkiewcz, Gabrielle Bierlein-De La Rosa, Cayce E. Dorrier, Mackenzie McKnight, Jeffrey F. DiBerto, Dipanwati Pati, Carol A. Gianessi, Olivia J. Hon, Greg Tipton, Zoe A. McElligott, Eric Delpire, Thomas L. Kash
ACS CHEMICAL NEUROSCIENCE
(2019)
Article
Biology
Laura A. Ewell, Kyle B. Fischer, Christian Leibold, Stefan Leutgeb, Jill K. Leutgeb
Correction
Neurosciences
J. Andrew Hardaway, Lindsay R. Halladay, Christopher M. Mazzone, Dipanwita Pati, Daniel W. Bloodgood, Michelle Kim, Jennifer Jensen, Jeffrey F. DiBerto, Kristen M. Boyt, Ami Shiddapur, Ava Erfani, Olivia J. Hon, Sofia Neira, Christina M. Stanhope, Jonathan A. Sugam, Michael P. Saddoris, Greg Tipton, Zoe McElligott, Thomas C. Jhou, Garret D. Stuber, Michael R. Bruchas, Cynthia M. Bulik, Andrew Holmes, Thomas L. Kash
Article
Biochemistry & Molecular Biology
Elizabeth K. Unger, Jacob P. Keller, Michael Altermatt, Ruqiang Liang, Aya Matsui, Chunyang Dong, Olivia J. Hon, Zi Yao, Junqing Sun, Samba Banala, Meghan E. Flanigan, David A. Jaffe, Samantha Hartanto, Jane Carlen, Grace O. Mizuno, Phillip M. Borden, Amol Shivange, Lindsay P. Cameron, Steffen Sinning, Suzanne M. Underhill, David E. Olson, Susan G. Amara, Duncan Temple Lang, Gary Rudnick, Jonathan S. Marvin, Luke D. Lavis, Henry A. Lester, Veronica A. Alvarez, Andrew J. Fisher, Jennifer A. Prescher, Thomas L. Kash, Vladimir Yarov-Yarovoy, Viviana Gradinaru, Loren L. Looger, Lin Tian