Development of novel antibacterial drugs to combat multiple resistant organisms
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Title
Development of novel antibacterial drugs to combat multiple resistant organisms
Authors
Keywords
New antibiotics, Multidrug resistance, FDA
Journal
LANGENBECKS ARCHIVES OF SURGERY
Volume 400, Issue 2, Pages 153-165
Publisher
Springer Nature
Online
2015-02-10
DOI
10.1007/s00423-015-1280-4
References
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- In VitroandIn VivoAntibacterial Activities of Omadacycline, a Novel Aminomethylcycline
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- (2013) L Silvia Munoz-Price et al. LANCET INFECTIOUS DISEASES
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- (2012) Kenneth S. Thomson ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
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- (2012) Trudy H. Grossman et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Unmet Medical Need in Infectious Diseases
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- (2012) George G Zhanel et al. Expert Review of Anti-Infective Therapy
- Activity of JNJ-Q2, a new fluoroquinolone, tested against contemporary pathogens isolated from patients with community-acquired bacterial pneumonia
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- A randomised, double-blind trial comparing ceftobiprole medocaril with ceftriaxone with or without linezolid for the treatment of patients with community-acquired pneumonia requiring hospitalisation
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