Journal
HFSP JOURNAL
Volume 3, Issue 6, Pages 373-378Publisher
HFSP PUBLISHING
DOI: 10.2976/1.3249971
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Funding
- NSF [0504239]
- ANR [05-NANO-062-03]
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Chromatin structure is a powerful tool to regulate eukaryotic transcription. Moreover, nucleosomes are constantly remodeled, disassembled, and reassembled in the body of transcribed genes. Here we propose a general model that explains, in quantitative terms, how transcription elongation affects nucleosome structure at a distance as a result of the positive torque the polymerases create as they translocate along DNA templates. [DOI: 10.2976/1.3249971]
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