4.2 Article

A NOVEL THREE-COMPONENT COUPLING REACTION OF ARYNES, ISOCYANIDES, AND CYANOFORMATES: A STRAIGHTFORWARD ACCESS TO CYANO-SUBSTITUTED IMINOISOBENZOFURANS

Journal

HETEROCYCLES
Volume 86, Issue 2, Pages 933-940

Publisher

Japan Inst Heterocyclic Chemistry
DOI: 10.3987/COM-12-S(N)77

Keywords

Aryne; Isocyanide; Cyanoformate; Three-Component Coupling; Oxygen Heterocycle

Funding

  1. JSPS [24550119]
  2. Grants-in-Aid for Scientific Research [24550119] Funding Source: KAKEN

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Iminoisobenzofuran derivatives have been prepared in moderate yields by the palladium-catalyzed three-component coupling reaction of arynes, isocyanides, and cyanoformates. This paper is dedicated to Professor Ei-ichi Negishi on the occasion of his 77th birthday.

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