Journal
HETEROCYCLES
Volume 81, Issue 9, Pages 2123-2130Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.3987/COM-10-12009
Keywords
Wicklowia aquatica; Fungus; Nonadride; Waquafranone; Antifungal Activity
Categories
Funding
- National Science Foundation [CHE-0315591]
- National Institutes of Health [GM 60600]
- Direct For Biological Sciences
- Division Of Environmental Biology [0844722] Funding Source: National Science Foundation
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Three new nonadride derivatives, tetrahydroepiheveadride (1), dideoxoepiheveadride (2) and deoxodihydroepiheveadride (3), and two new C-9 compounds, waquafranone A (7) and B (8), which were suggestive of precursors of nonadrides, along with other known compounds epiheveadride (4), deoxoepiheveadride (5), dihydroepiheveadride (6), sydonic acid (9), hydroxysydonic acid (10), folipastatin (11), and agonodepside B (12), from the newly described freshwater aquatic fungus Wicklowia aquatica. The chemical structures of 1 - 12 were elucidated by the spectroscopic and chemical investigation and, comparison to literature data.
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