Article
Pediatrics
Laurens D. Eeftinck Schattenkerk, Gijsbert D. Musters, S. E. Le Coultre, Wouter J. de Jonge, L. W. Ernest van Heurn, Joep Pm Derikx
Summary: This study identified the incidence of incisional hernia following abdominal surgery in infants to be 5.2%. High risk diseases included necrotizing enterocolitis, gastroschisis, and omphalocele. Risk factors for incisional hernia included wound infection, preterm birth, and history of stoma.
JOURNAL OF PEDIATRIC SURGERY
(2021)
Article
Surgery
A. V. Andriyashkin, K. M. Loban, A. A. Kalinina, G. B. Ivakhov, I. A. Zolotukhin, A. V. Sazhin
Summary: The incidence of postoperative VTE is high in patients after incisional hernia repair, with distal DVT being the predominant event. Component separation, duration of operation, and body mass index are statistically significant risk factors for VTE in patients undergoing surgery for incisional hernia.
Article
Surgery
Alberto G. Barranquero, Juan Jose Espert, Maria Magdalena Llompart Coll, Yolanda Maestre Gonzalez, Cristina Gas Ruiz, Jorge Juan Olsina Kissler, Rafael Villalobos Mori
Summary: The sandwich technique for parastomal hernia repair demonstrated a recurrence rate of 7.9% in this study, with postoperative complications emerging as the primary risk factor for hernia recurrence. The study was conducted in two tertiary referral centers in Catalonia, Spain, and included consecutive patients who underwent parastomal hernia repair using the sandwich technique between January 1, 2016 and December 31, 2021.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Medicine, General & Internal
Marine Goullieux, Fawaz Abo-Alhassan, Remi Vieira-Da-Silva, Papet Lauranne, Adeline Guiraud, Pablo Ortega-Deballon
Summary: This study aimed to compare the likelihood of bowel obstruction based on the placement of the mesh in ventral hernia repairs. The results showed no significant difference in terms of bowel obstruction between intraperitoneal and extraperitoneal mesh placement, but all cases of obstruction occurred in the intraperitoneal group.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Surgery
Timothy R. Holden, Bradley S. Kushner, Julia L. Hamilton, Britta Han, Sara E. Holden
Summary: This study found that polypharmacy is common in older adults undergoing TAR and is associated with in-hospital complications, postoperative delirium, cardiac events, ICU stay, length of stay, and discharge to a skilled nursing facility.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Surgery
Quintin P. Solano, Jyothi R. Thumma, Cody Mullens, Ryan Howard, Anne Ehlers, Lia Delaney, Brian Fry, Mary Shen, Michael Englesbe, Justin Dimick, Dana Telem
Summary: This study evaluated the hospital-level variation of ventral or incisional hernia repair in the kidney transplant population and found significant differences in hernia repair rates among different hospitals. Patient and hospital characteristics also varied across tertiles, particularly in diabetes and obesity.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Surgery
Oscar A. Olavarria, Naila H. Dhanani, Karla Bernardi, Julie L. Holihan, Cynthia S. Bell, Tien C. Ko, Mike K. Liang
Summary: Prophylactic mesh reinforcement of midline laparotomy closures appears to be effective in preventing incisional hernias, but it also increases the risk of surgical site occurrences.
Article
Multidisciplinary Sciences
Micaela Piccoli, Francesca Pecchini, Gaetano Vetrone, Romano Linguerri, Giuliano Sarro, Umberto Rivolta, Amedeo Elio, Gianluca Piccirillo, Giuseppe Faillace, Emilia Masci, Davide Guglielminetti, Chiara Santorelli, Giorgio Soliani, Margherita Koleva Radica, Vincenzo Trapani, Domenico Marchi, Johanna Chester, Luca Leonardi, Silvia Neri
Summary: This study retrospectively evaluated predictive factors of recurrence following LVHR and found that IH patients had a higher risk of recurrence compared to PH patients. LVHR with a light-weight polypropylene mesh has low complications and is appropriate for both IH and PH.
SCIENTIFIC REPORTS
(2022)
Article
Surgery
Deangelo H. Ferguson, Ciara G. Smith, Olubode A. Olufajo, Ahmad Zeineddin, Mallory Williams
Summary: According to the study, patients with COPD, Obesity, DM, and lower income status are more likely to experience complications after component separation surgery.
JOURNAL OF SURGICAL RESEARCH
(2021)
Article
Surgery
O. Y. Kudsi, K. Chang, N. Bou-Ayash, F. Gokcal
Summary: Comparing three methods of robotic PVH repair, it was found that rRM repair allows for use of larger meshes for larger defects but is associated with higher-grade complications; rTAPP repair results in the lowest morbidity and offers the highest mesh-to-defect ratio for smaller hernias; the rRM group had longer operative time.
Article
Surgery
Alberto G. Barranquero, Rafael Villalobos Mori, Yolanda Maestre Gonzalez, Gian Pier Protti, Guillermo Lopez Soler, Fernando Villarreal Leon, Irvin Jair Gonzalez Alfaro, Jorge Juan Olsina Kissler
Summary: This study evaluated the results of using the Parietex(TM) Composite Ventral Patch for ventral hernia repair with the open intraperitoneal onlay mesh technique. The results showed that the open IPOM technique with a preformed patch offered satisfactory results for the treatment of ventral and incisional hernias.
ANZ JOURNAL OF SURGERY
(2023)
Article
Surgery
Atsushi Morito, Keisuke Kosumi, Tatsuo Kubota, Shinsei Yumoto, Takashi Matsumoto, Kosuke Mima, Mitsuhiro Inoue, Takao Mizumoto, Nobutomo Miyanari, Hideo Baba
Summary: This study found that internal inguinal hernia and hernia size >= 3 cm were considered risk factors for postoperative seroma/hematoma formation after TAPP.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Surgery
Hironori Ishibashi, Ryo Wakejima, Ayaka Asakawa, Yusuke Sugita, Yuya Ishikawa, Mariko Hanafusa, Shunichi Baba, Yasuhiro Nakashima, Katsutoshi Seto, Kenichi Okubo
Summary: This study identified age, peripheral vascular disease, depression, and current smoking status as independent risk factors for postoperative delirium after anatomical lung resection for lung cancer. Smoking cessation for at least four weeks before surgery is recommended to reduce the incidence of postoperative delirium. The study also showed differences in overall survival between delirium and non-delirium groups, but after propensity score matching, there were no significant differences in survival outcomes between the two groups.
WORLD JOURNAL OF SURGERY
(2022)
Article
Health Care Sciences & Services
Anas Taha, Bassey Enodien, Vincent Ochs, Marta Bachmann, Maike Gripp, Michel Adamina, Stephanie Taha-Mehlitz, Daniel Frey
Summary: This study identified epidemiological and procedure related factors in ventral hernia repairs and their influence on surgical training. Factors influencing costs and revenue enhancement in VHR were analyzed, providing recommendations on improving financial results, training, and maintaining the profitability of hospitals in the future.
Article
Surgery
H. Hoffmann, F. Koeckerling, D. Adolf, F. Mayer, D. Weyhe, W. Reinpold, R. Fortelny, P. Kirchhoff
Summary: The outcomes of recurrent incisional hernia repair are significantly associated with potential influencing factors, which are very similar to the factors seen in primary incisional hernia repair. The impact of the primary incisional hernia repair technique, namely laparoscopic IPOM versus open mesh techniques, on the outcome of recurrent incisional hernia repair seems less pronounced than anticipated.
Letter
Rheumatology
Samy Hakroush, Jonas Franz, Joerg Larsen, Peter Korsten, Martin Sebastian Winkler, Bjoern Tampe
ANNALS OF THE RHEUMATIC DISEASES
(2023)
Letter
Rheumatology
Martin Sebastian Winkler, Peter Korsten, Claudia Binder, Bjoern Tampe
ANNALS OF THE RHEUMATIC DISEASES
(2023)
Letter
Rheumatology
Desiree Tampe, Martin S. Winkler, Peter Korsten, Samy Hakroush, Onnen Moerer, Bjoern Tampe
ANNALS OF THE RHEUMATIC DISEASES
(2023)
Letter
Rheumatology
Desiree Tampe, Peter Korsten, Samy Hakroush, Martin Sebastian Winkler, Bjoern Tampe
ANNALS OF THE RHEUMATIC DISEASES
(2023)
Article
Biochemistry & Molecular Biology
Markus Hoffmann, Nadine Krueger, Sebastian Schulz, Anne Cossmann, Cheila Rocha, Amy Kempf, Inga Nehlmeier, Luise Graichen, Anna-Sophie Moldenhauer, Martin S. Winkler, Martin Lier, Alexandra Dopfer-Jablonka, Hans-Martin Jaeck, Georg M. N. Behrens, Stefan Poehlmann
Summary: The Omicron variant of SARS-CoV-2 is spreading rapidly and shows resistance to most therapeutic antibodies. It also evades neutralization by antibodies induced by infection or vaccination more efficiently than the Delta variant. This suggests that therapeutic antibodies may not be effective against the Omicron variant, and double vaccination with BNT162b2 may not provide adequate protection against severe disease caused by this variant.
Editorial Material
Immunology
Prerna Arora, Amy Kempf, Inga Nehlmeier, Luise Graichen, Martin S. Winkler, Martin Lier, Sebastian Schulz, Hans-Martin Jaeck, Stefan Poehlmann, Markus Hoffmann
Summary: Since the beginning of the COVID-19 pandemic, various SARS-CoV-2 variants have emerged, with mutations in the viral spike (S) protein playing a critical role in the virus's infectivity, transmissibility, pathogenicity, and ability to evade neutralizing antibodies.
CELLULAR & MOLECULAR IMMUNOLOGY
(2022)
Review
Oncology
Anne Hendricks, Sophie Mueller, Martin Fassnacht, Christoph-Thomas Germer, Verena A. Wiegering, Armin Wiegering, Joachim Reibetanz
Summary: This study conducted a systematic review and meta-analysis to determine the oncologic value of locoregional lymphadenectomy (LND) in adrenocortical cancer (ACC). The results showed that LND can provide oncologic benefits for patients with localized ACC (stage I-III) undergoing curative-intended surgery.
Letter
Infectious Diseases
Prerna Arora, Lu Zhang, Cheila Rocha, Anzhalika Sidarovich, Amy Kempf, Sebastian Schulz, Anne Cossmann, Bernhard Manger, Eva Baier, Bjoern Tampe, Onnen Moerer, Steffen Dickel, Alexandra Dopfer-Jablonka, Hans-Martin Jaeck, Georg M. N. Behrens, Martin S. Winkler, Stefan Poehlmann, Markus Hoffmann
LANCET INFECTIOUS DISEASES
(2022)
Article
Respiratory System
Philip Baum, Martin E. Eichhorn, Johannes Diers, Armin Wiegering, Laura V. Klotz, Hauke Winter
Summary: This study analyzed sex-specific differences after lung cancer resections and found that women who underwent lung cancer surgery in Germany were younger, had fewer comorbidities, and had lower in-hospital mortality and postoperative complication rates compared to men.
Article
Microbiology
Markus Hoffmann, Anzhalika Sidarovich, Prerna Arora, Nadine Krueger, Inga Nehlmeier, Amy Kempf, Luise Graichen, Martin S. Winkler, Daniela Niemeyer, Christine Goffinet, Christian Drosten, Sebastian Schulz, Hans-Martin Jaeck, Stefan Poehlmann
Summary: The naturally occurring mutation E484D allows SARS-CoV-2 to enter host cells independently of ACE2 and renders it insensitive to the neutralizing antibody Imdevimab, which is used for COVID-19 therapy.
Article
Oncology
Philip Baum, Hauke Winter, Martin E. Eichhorn, Romina M. Roesch, Samantha Taber, Petros Christopoulos, Armin Wiegering, Jacopo Lenzi
Summary: The mortality trends of lung cancer in Europe and Northern America show variations, with an overall decrease but a significant increase in female mortality in countries other than the USA. This may be influenced by tobacco control, screening, therapeutic advances, and access to healthcare.
EUROPEAN JOURNAL OF CANCER
(2022)
Letter
Oncology
Philip Baum, Jacopo Lenzi, Samantha Taber, Hauke Winter, Armin Wiegering
JOURNAL OF CLINICAL ONCOLOGY
(2022)
Article
Multidisciplinary Sciences
Friedrich Anger, Sven Lichthardt, Imme Haubitz, Johanna Wagner, Stefan Loeb, Heinz Johannes Buhr, Christoph-Thomas Germer, Armin Wiegering
Summary: Emergency colorectal surgery in Germany has equal 30-day mortality and postoperative course throughout the week, but surgery performed during the week seems to be associated with a higher rate of severe postoperative complications and reoperation.
Article
Environmental Sciences
Anna Widder, Matthias Kelm, Joachim Reibetanz, Armin Wiegering, Niels Matthes, Christoph-Thomas Germer, Florian Seyfried, Sven Flemming
Summary: This study analyzed the postoperative inflammation status, short-term outcomes, and cost-effectiveness of robotic-assisted versus laparoscopic left hemicolectomy. The results showed that robotic-assisted surgery led to decreased hospital stay, lower complication rates, and reduced systemic stress response compared to laparoscopic surgery. Therefore, robotic-assisted left hemicolectomy is a safe and cost-effective procedure that may improve patient outcomes.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Critical Care Medicine
Martin S. Winkler, Marcin F. Osuchowski, Didier Payen, Antoni Torres, Steffen Dickel, Tomasz Skirecki
Summary: A clear indication for the use of glucocorticosteroids (GCs) in severe COVID-19 has been established, potentially leading to a wider use of GCs in critical illnesses. To better understand the heterogeneity of critical illness and optimize the use of GCs within the precision medicine approach, this study formulates ten major questions that need to be answered.