Article
Biotechnology & Applied Microbiology
Thomas E. Witte, Linda J. Harris, Hai D. T. Nguyen, Anne Hermans, Anne Johnston, Amanda Sproule, Jeremy R. Dettman, Christopher N. Boddy, David P. Overy
Summary: This study investigated the biosynthetic potential of F. poae isolates from Eastern Canada, revealing the presence of lineage-specific accessory chromosomes and confirming the production of apicidins in some isolates. The data presented here provide valuable insights into accessory chromosome evolution and the biosynthetic capabilities of F. poae.
Article
Mathematics, Applied
A. Khoshkenar, M. Ilie, K. Hosseini, D. Baleanu, S. Salahshour, C. Park, J. R. Lee
Summary: In this paper, a power series based on the M-fractional derivative is introduced, and new definitions, theorems, and corollaries regarding the power series in the M sense are presented and formally proved. Several ordinary differential equations involving the M-fractional derivative are solved to examine the validity of the results presented in the study.
Review
Plant Sciences
Masoumeh Khodaverdi, Mark D. Mullinger, Hannah R. Shafer, Jill C. Preston
Summary: The perennial non-core genus Melica has the potential to be an additional model for understanding the genetic basis of trait diversification in Pooideae grasses. It possesses features such as fast generation time, perenniality, and interesting variation in physiology and morphology. The next step is to generate a genome-based phylogeny and transformation tools for functional analysis.
Review
Biochemistry & Molecular Biology
Jovan Komluski, Eva H. Stukenbrock, Michael Habig
Summary: This review provides an overview and comparison of the possible mechanisms causing non-Mendelian transmission or meiotic drives of fungal accessory chromosomes, and discusses the structural traits of fungal accessory chromosomes affecting their meiotic transmission.
CHROMOSOME RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Fanny E. Hartmann, Sandra Lorena Ament-Velasquez, Aaron A. Vogan, Valerie Gautier, Stephanie Le Prieur, Myriam Berramdane, Alodie Snirc, Hanna Johannesson, Pierre Grognet, Fabienne Malagnac, Philippe Silar, Tatiana Giraud
Summary: The study reveals the presence of nonrecombining regions around the mating-type locus in the fungus Podospora anserina and related species, leading to occasional recombination due to the labile and polymorphic nature of these regions. The size and location of the nonrecombining region vary between strains and species, resulting in differences in heterozygosity levels. Low levels of heterozygosity suggest low but nonnull outcrossing rates in nature for these pseudohomothallic fungi, contributing to our understanding of mating-type chromosome evolution and mating systems.
MOLECULAR BIOLOGY AND EVOLUTION
(2021)
Review
Microbiology
Thomas E. Witte, Nicolas Villeneuve, Christopher N. Boddy, David P. Overy
Summary: Accessory chromosomes in fungi are strain-specific chromosomes that harbor pathogenicity or virulence factor genes, and play a role in secondary metabolism. Horizontal transfer between strains and dynamic crosstalk with core chromosomes make accessory chromosomes of interest for their evolutionary impact on secondary metabolite gene clusters. Various studies have explored the role of accessory chromosomes in toxin biosynthesis, offering fresh insights into the evolution of biosynthetic enzymes and regulatory mechanisms.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Rajan Giri, Hari K. Namballa, Ananta Sarker, Ian Alberts, Wayne W. Harding
Summary: The study synthesized and evaluated a series of 1-phenylbenzazepine derivatives with different substituents, revealing that the N-methyl group exhibits strong affinity towards D1R. Additionally, the 8-hydroxy-7-methoxy substituent shows stronger D1R affinity compared to the catechol moiety, while the C2' substituent has minimal impact on D1R selectivity.
BIOORGANIC CHEMISTRY
(2022)
Article
Mathematics, Applied
Wenjia Xie, Zhengyu Tian, Ye Zhang, Hang Yu, Weijie Ren
Summary: The paper conducts continuous research to explore the mechanism of numerical shock instabilities of Godunov-type schemes for strong shocks. Through dissipation analysis and numerical experiments, it is clarified that inadequate entropy production inside the numerical shock structure may be the cause of instability. A general entropy-control technique is developed to improve the robustness of Godunov-type schemes at strong shocks without introducing additional numerical dissipation, resulting in good performance in accuracy and robustness for various test cases.
COMPUTERS & MATHEMATICS WITH APPLICATIONS
(2021)
Article
Biochemistry & Molecular Biology
R. Alan Aitken, Andrew D. Harper, Ryan A. Inwood
Summary: The limitations of the reaction between 14 ortho-functionalised 2-aryloxazolines and butyllithium were investigated, revealing challenges in the Wittig rearrangement. While good diastereoselectivity was achieved in some compounds for asymmetric Wittig rearrangement, racemisation issues were encountered upon hydrolysis.
Article
Radiology, Nuclear Medicine & Medical Imaging
Liqiang Sun, Liqing Dong, Xiuchuan Jia, Yingmin Chen, Shuqian Zhang, Hui Zhang
Summary: Accessory Cardiac Bronchus (ACB) is a rare tracheobronchial branching abnormality that originates from the medial wall of the intermediate or main bronchus and directs towards the heart. This study reports 40 cases of ACB detected in routine spiral computed tomography (CT) examinations, with a frequency of 0.39%. ACB showed three types, with different origins and characteristics.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2022)
Article
Biotechnology & Applied Microbiology
Tomislav Cernava
Summary: Biological control is a powerful alternative in agriculture, but many potential biocontrol agents based on microorganisms fail during the transition to practicable applications. The key to success lies in targeted further experimentation and optimization.
BIOLOGICAL CONTROL
(2021)
Editorial Material
Genetics & Heredity
Thomas M. Guerin, Stephane Marcand
Summary: This article discusses Barbara McClintock's significant research and recent findings that shed light on the mechanism of chromatin bridge breakage in yeast and animal cells.
TRENDS IN GENETICS
(2022)
Article
Multidisciplinary Sciences
Andy C. W. Lui, Kah Chee Pow, Nan Lin, Lydia Pui Ying Lam, Guoquan Liu, Ian D. Godwin, Zhuming Fan, Chen Jing Khoo, Yuki Tobimatsu, Lanxiang Wang, Quan Hao, Clive Lo
Summary: The study reveals that sorghum and wild sugarcane accumulate different types of O-methylated stilbenes due to major differences in catalytic regioselectivities of O-methyltransferases. This research reports the inherent ability of two Saccharinae grasses to produce regioselectively O-methylated stilbenes. The findings have important implications for the bioengineering synthesis of O-methylated stilbenes.
NATURE COMMUNICATIONS
(2023)
Article
Engineering, Electrical & Electronic
Yajuan Liu, Jiayu Li, Fang Fang, Ju H. Park
Summary: A novel nonfragile sampled-data control scheme is presented for multi-agent systems with communication delays, aiming to reduce the computational burden and minimize the impact of controller uncertainties on system stability. By utilizing the state information of some intervals, a modified looped-functional is introduced, and the improved sufficient conditions for consensus of the MASs are derived in the form of linear matrix inequalities using the constructed Lyapunov functional and the free weighting matrix method. Two numerical simulations demonstrate the better performance of the proposed methods compared to existing literature.
IEEE TRANSACTIONS ON SIGNAL AND INFORMATION PROCESSING OVER NETWORKS
(2022)
Article
Biochemistry & Molecular Biology
Yash Pal Singh, Gauri Shankar, Shagufta Jahan, Gourav Singh, Navneet Kumar, Atanu Barik, Prabhat Upadhyay, Lovejit Singh, Kajal Kamble, Gireesh Kumar Singh, Sanjay Tiwari, Prabha Garg, Sarika Gupta, Gyan Modi
Summary: This study developed a novel multifunctional molecule, 13b, which showed potent inhibition of AChE and BChE, excellent antioxidant properties, and demonstrated a protective effect in neuronal toxicity experiments. Furthermore, 13b was able to cross the blood-brain barrier, indicating its potential value in the treatment of AD.
BIOORGANIC & MEDICINAL CHEMISTRY
(2021)
