Abnormality of autophagic function and cathepsin expression in the liver from patients with non-alcoholic fatty liver disease

A cathepsin L-specific inhibitor preferentially inhibits degradation of autophagosomal LC3 and GABARAP in HeLa and Huh-7 cells

(2014) Takashi Ueno et al.   Autophagy

Active cathepsins B, L, and S in murine and human pancreatitis

(2012) Victoria Lyo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Suppression of autophagy sensitizes Kupffer cells to endotoxin

(2012) Hiroo Fukada et al.   HEPATOLOGY RESEARCH

Changes in Autophagic Response in Patients with Chronic Hepatitis C Virus Infection

(2011) Pierre-Emmanuel Rautou et al.   AMERICAN JOURNAL OF PATHOLOGY

Hepatic steatosis inhibits autophagic proteolysis via impairment of autophagosomal acidification and cathepsin expression

(2011) Yoshihiro Inami et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Functions of Autophagy in Hepatic and Pancreatic Physiology and Disease

(2011) Mark J. Czaja   GASTROENTEROLOGY

Pharmacological therapy of nonalcoholic steatohepatitis

(2011) Mariko Hojo et al.   HEPATOLOGY RESEARCH

Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells

(2011) Yoshihiro Inami et al.   JOURNAL OF CELL BIOLOGY

Autophagy by hepatitis B virus and for hepatitis B virus

(2010) Donna Sir et al.   Autophagy

Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance

(2010) Ling Yang et al.   Cell Metabolism

Autophagy mediates the process of cellular senescence characterizing bile duct damages in primary biliary cirrhosis

(2010) Motoko Sasaki et al.   LABORATORY INVESTIGATION

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

The early autophagic pathway is activated by hepatitis B virus and required for viral DNA replication

(2010) D. Sir et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of CAA0225, a Novel Inhibitor Specific for Cathepsin L, as a Probe for Autophagic Proteolysis

(2009) Katsuyuki Takahashi et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Hepatic Autophagy Is Suppressed in the Presence of Insulin Resistance and Hyperinsulinemia

(2009) Hui-Yu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of hepatitis C virus replication by chloroquine targeting virus-associated autophagy

(2009) Tomokazu Mizui et al.   JOURNAL OF GASTROENTEROLOGY

Activity-Based Proteome Profiling of Hepatoma Cells during Hepatitis C Virus Replication Using Protease Substrate Probes

(2009) David R. Blais et al.   JOURNAL OF PROTEOME RESEARCH

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

Autophagy in the liver

(2008) Xiao-Ming Yin et al.   HEPATOLOGY

Induction of incomplete autophagic response by hepatitis C virus via the unfolded protein response

(2008) Donna Sir et al.   HEPATOLOGY

Liver diseases and metabolic syndrome

(2008) Sumio Watanabe et al.   JOURNAL OF GASTROENTEROLOGY

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production

(2008) Tatsuya Saitoh et al.   NATURE

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE

Cysteine cathepsins: Cellular roadmap to different functions

(2007) Klaudia Brix et al.   BIOCHIMIE