Strategies to produce hepatocytes and hepatocyte-like cells from pluripotent stem cells

Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors

(2011) Pengyu Huang et al.   NATURE

Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors

(2011) Sayaka Sekiya et al.   NATURE

Efficient and Directive Generation of Two Distinct Endoderm Lineages from Human ESCs and iPSCs by Differentiation Stage-Specific SOX17 Transduction

(2011) Kazuo Takayama et al.   PLoS One

Induction of a mature hepatocyte phenotype in adult liver derived progenitor cells by ectopic expression of transcription factors

(2011) Razvan Iacob et al.   Stem Cell Research

Comparison of Hepatic-like Cell Production from Human Embryonic Stem Cells and Adult Liver Progenitor Cells: CAR Transduction Activates a Battery of Detoxification Genes

(2011) Natalie Funakoshi et al.   Stem Cell Reviews and Reports

Functional Characterization of Hepatocytes for Cell Transplantation: Customized Cell Preparation for Each Receptor

(2010) A. Bonora-Centelles et al.   CELL TRANSPLANTATION

Hepatic Differentiation of Mouse iPS Cells in Vitro

(2010) Masaya Iwamuro et al.   CELL TRANSPLANTATION

Generation of murine hepatic lineage cells from induced pluripotent stem cells

(2010) Hui Gai et al.   DIFFERENTIATION

Induced pluripotency: history, mechanisms, and applications

(2010) M. Stadtfeld et al.   GENES & DEVELOPMENT

Generation of endoderm-derived human induced pluripotent stem cells from primary hepatocytes

(2010) Hua Liu et al.   HEPATOLOGY

Efficient Generation of Hepatoblasts From Human ES Cells and iPS Cells by Transient Overexpression of Homeobox Gene HEX

(2010) Mitsuru Inamura et al.   MOLECULAR THERAPY

Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells

(2010) Jose M Polo et al.   NATURE BIOTECHNOLOGY

Human Embryonic and Rat Adult Stem Cells with Primitive Endoderm-Like Phenotype Can Be Fated to Definitive Endoderm, and Finally Hepatocyte-Like Cells

(2010) Philip Roelandt et al.   PLoS One

Oct4-Induced Pluripotency in Adult Neural Stem Cells

(2009) Jeong Beom Kim et al.   CELL

Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells

(2009) Zhihua Song et al.   CELL RESEARCH

Functional Assessment of the Quality of Human Hepatocyte Preparations for Cell Transplantation

(2009) María Teresa Donato et al.   CELL TRANSPLANTATION

Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells

(2009) Karim Si-Tayeb et al.   HEPATOLOGY

Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development

(2009) Thomas Touboul et al.   HEPATOLOGY

Hepatocyte-like cells derived from human embryonic stem cells specifically via definitive endoderm and a progenitor stage

(2009) Gabriella Brolén et al.   JOURNAL OF BIOTECHNOLOGY

Virus-free induction of pluripotency and subsequent excision of reprogramming factors

(2009) Keisuke Kaji et al.   NATURE

piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

(2009) Knut Woltjen et al.   NATURE

Suppression of induced pluripotent stem cell generation by the p53–p21 pathway

(2009) Hyenjong Hong et al.   NATURE

Immortalization eliminates a roadblock during cellular reprogramming into iPS cells

(2009) Jochen Utikal et al.   NATURE

Derivation and Characterization of Hepatic Progenitor Cells from Human Embryonic Stem Cells

(2009) Dongxin Zhao et al.   PLoS One

Hepatic Differentiation of Mouse Embryonic Stem Cells in Three-Dimensional Polymer Scaffolds

(2009) Tao Liu et al.   TISSUE ENGINEERING PART A

Stem Cells and Early Lineage Development

(2008) Janet Rossant   CELL

Stem cell therapy for inherited metabolic disorders of the liver

(2008) Susan Ellor et al.   EXPERIMENTAL HEMATOLOGY

Differentiation and Transplantation of Human Embryonic Stem Cell–Derived Hepatocytes

(2008) Hesham Basma et al.   GASTROENTEROLOGY

The promise of human induced pluripotent stem cells for research and therapy

(2008) Shin-ichi Nishikawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Generation of Pluripotent Stem Cells from Adult Mouse Liver and Stomach Cells

(2008) T. Aoi et al.   SCIENCE

Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors

(2008) K. Okita et al.   SCIENCE

Efficient Differentiation of Functional Hepatocytes from Human Embryonic Stem Cells

(2008) Sadhana Agarwal et al.   STEM CELLS

Three-Dimensional Primary Hepatocyte Culture in Synthetic Self-Assembling Peptide Hydrogel

(2008) Sihong Wang et al.   TISSUE ENGINEERING PART A