Review
Biochemistry & Molecular Biology
Ronni Baran, Daniela Grimm, Manfred Infanger, Markus Wehland
Summary: OSA is a common disease affecting millions worldwide, with CPAP therapy being a common treatment method to prevent complications such as hypertension by improving airway patency.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Clinical Neurology
Yi Cai, Hailey M. Juszczak, Emily K. Cope, Andrew N. Goldberg
Summary: Recent evidence suggests a bidirectional relationship between obstructive sleep apnea and microbiota composition, where sleep quality and microbiota alterations influence each other. Animal model studies support the idea that the microbiome mediates disease states associated with obstructive sleep apnea, and potential treatment options include probiotics, prebiotics, and microbiota transplantation.
Article
Nutrition & Dietetics
Silvia Conde, Fatima O. Martins, Sara S. Dias, Paula Pinto, Cristina Barbara, Emilia C. Monteiro
Summary: This study investigated the effect of caffeine consumption on patients with obstructive sleep apnea (OSA) and found that higher caffeine consumption does not alter the variables related to the disease.
Article
Peripheral Vascular Disease
Min Ru Chee, Jesse Hoo, Renata Libianto, Stella M. Gwini, Garun Hamilton, Om Narayan, Morag J. Young, Peter J. Fuller, Jun Yang
Summary: This study found a high prevalence of possible or likely primary aldosteronism among patients with both obstructive sleep apnea and hypertension, suggesting that they should be routinely screened for PA. No correlation was found between aldosterone, renin, or aldosterone:renin ratio and the apnea-hypopnea index, indicating the need for further research on the relationship between these conditions.
Article
Clinical Neurology
Jacqueline H. Geer, Guido J. Falcone, Kevin N. Vanent, Audrey C. Leasure, Daniel Woo, Jennifer R. Molano, Lauren H. Sansing, Carl D. Langefeld, Margaret A. Pisani, Henry K. Yaggi, Kevin N. Sheth
Summary: The study found that obstructive sleep apnea (OSA) is associated with the risk of intracerebral hemorrhage (ICH). Cases with OSA were more likely to be male and have hypertension, heart disease, hyperlipidemia, and higher body mass index compared to those without OSA. Logistic regression analysis showed that OSA is a risk factor for ICH.
Article
Clinical Neurology
Le Wang, Donghui Wei, Jing Zhang, Jie Cao, Xinxin Zhang
Summary: This cross-sectional study found a significant positive association between REM AHI and hypertension in OSA patients, with a more pronounced effect in female patients.
NATURE AND SCIENCE OF SLEEP
(2022)
Article
Clinical Neurology
Ning Xia, Hao Wang, Yu Chen, Xiao-Jun Fan, Xiu-Hong Nie
Summary: This study aimed to explore the relationship between sleep efficiency (SE) and the prevalence of hypertension in Chinese obstructive sleep apnea (OSA) patients. The results showed that OSA patients with low SE were more likely to have hypertension, especially in female, younger ages, obese, moderate and severe OSA patients, compared to primary snorers.
NATURE AND SCIENCE OF SLEEP
(2023)
Article
Respiratory System
Soraya Giatti, Ronaldo B. Santos, Aline N. Aielo, Wagner A. Silva, Barbara K. Parise, Silvana P. Souza, Andrea Pio-Abreu, Luiz A. Bortolotto, Paulo A. Lotufo, Isabela M. Bensenor, Luciano F. Drager
Summary: The study found that the association between urinary sodium excretion and obstructive sleep apnea (OSA) was not significant overall, but did have an impact on patients with hypertension.
ANNALS OF THE AMERICAN THORACIC SOCIETY
(2021)
Article
Clinical Neurology
Riku Huttunen, Timo Leppanen, Brett Duce, Arie Oksenberg, Sami Myllymaa, Juha Toyras, Henri Korkalainen
Summary: This study developed an automatic sleep staging method based on photoplethysmography (PPG) signal, successfully differentiating between obstructive sleep apnea (OSA) severity categories and revealing that better sleep continuity evaluation results are achieved using shorter epoch-to-epoch intervals.
Article
Psychiatry
Xuan Zhang, Ning Zhang, Yang Yang, Shuo Wang, Ping Yu, Bo-Yuan Guan, Chun-Xue Wang
Summary: This retrospective study explored the characteristics and treatment status of obstructive sleep apnea (OSA) patients with hypertension. The study found that patients in the severe group had higher BMI, higher N1% and lower N2%, average, and minimum blood oxygen. The acceptance of titration therapy among OSA patients with hypertension was low.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Biochemistry & Molecular Biology
Piotr Macek, Rafal Poreba, Pawel Gac, Katarzyna Bogunia-Kubik, Marta Dratwa, Mieszko Wieckiewicz, Anna Wojakowska, Monika Michalek-Zrabkowska, Grzegorz Mazur, Helena Martynowicz
Summary: This study found no relationship between obstructive sleep apnea (OSA) and TERT SNPs. However, SNPs of the TERT gene were found to be associated with hypertension and diabetes prevalence.
Article
Clinical Neurology
Catherine Falla, Alan Young, Alun Pope, Denise M. O'Driscoll
Summary: Respiratory events during REM sleep are significantly associated with morning hypertensive blood pressure, while the relationship with evening hypertensive blood pressure is not significant. Age and BMI are independent factors influencing morning hypertension.
Article
Cardiac & Cardiovascular Systems
Rong Ren, Ye Zhang, Linghui Yang, Virend K. Somers, Naima Covassin, Xiangdong Tang
Summary: Sleep fragmentation is independently associated with hypertension in patients with obstructive sleep apnea (OSA).
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Review
Medicine, General & Internal
Servet Altay, Selma Firat, Yuksel Peker, TURCOSACT Collaborators
Summary: Hypertension is a global health issue and a major risk factor for cardiovascular and cerebrovascular diseases. Obstructive sleep apnea is characterized by recurrent episodes of breathing pauses and reduced airflow due to upper airway obstruction. There is increasing evidence of a link between obstructive sleep apnea and hypertension. Optimal blood pressure control is recommended as the primary treatment for hypertensive patients with obstructive sleep apnea.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Peripheral Vascular Disease
Kazuomi Kario, Douglas A. Hettrick, Aleksander Prejbisz, Andrzej Januszewicz
Summary: There is a bidirectional, causal relationship between obstructive sleep apnea (OSA) and hypertension, with hypoxia/hypercapnia-related sympathetic activation being the key mechanism. While continuous positive airway pressure is the gold standard therapy for OSA, its effects on blood pressure are modest. Antihypertensive agents targeting sympathetic pathways or the renin-angiotensin-aldosterone system may have potential in patients with comorbid hypertension and OSA.
Article
Medicine, General & Internal
Jessica Webb, Alexandra Brightwell, Pamela Sarkar, Roy Rabbie, Indranil Chakravorty
POSTGRADUATE MEDICAL JOURNAL
(2015)
Editorial Material
Medicine, General & Internal
Indranil Chakravorty
BRITISH JOURNAL OF HOSPITAL MEDICINE
(2018)
Article
Respiratory System
Linda Perkins-Porras, Muhammad Riaz, Adeoba Okekunle, Svitlana Zhelezna, Indranil Chakravorty, Michael Ussher
CHRONIC RESPIRATORY DISEASE
(2018)
Review
Cardiac & Cardiovascular Systems
Angshu Bhowmik, Kamaljeet Chahal, Gillian Austin, Indranil Chakravorty
RESPIRATORY MEDICINE
(2009)
Article
Respiratory System
Indranil Chakravorty, Kamaljit Chahal, Gillian Austin
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
(2011)
Meeting Abstract
Respiratory System
Shairana Naleem, Indranil Chakravorty
EUROPEAN RESPIRATORY JOURNAL
(2013)
Meeting Abstract
Respiratory System
Tamina Khalil, Hannah Walton, Wing Ng, Indranil Chakravorty
EUROPEAN RESPIRATORY JOURNAL
(2013)
Meeting Abstract
Respiratory System
Aisha McClintock-Tiongco, Arjun Patel, Indranil Chakravorty
EUROPEAN RESPIRATORY JOURNAL
(2012)
Meeting Abstract
Critical Care Medicine
C. Brown, G. Austin, J. McGowan, I. Chakravorty
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2009)
Meeting Abstract
Critical Care Medicine
T. Khalil, K. -W. Ng, W. Fleming-Nouri, A. K. Sarnowski, A. Field, I. Chakravorty
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2014)
Meeting Abstract
Critical Care Medicine
S. Naleem, V. Holme, N. Gosling, I. Chakravorty
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2013)
Meeting Abstract
Critical Care Medicine
I. Chakravorty, C. Fasakin, G. Austin, C. Timbury, C. Basu
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2011)
Meeting Abstract
Critical Care Medicine
V. Joshi, M. Penna, C. Wotton, E. Firth, I. Chakravorty
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2010)
Meeting Abstract
Critical Care Medicine
M. Sivalingam, S. Mouatt, K. Hall, I. Chakravorty, K. Farrington
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2009)