Journal
HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA
Volume 24, Issue 4, Pages 777-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.hoc.2010.05.003
Keywords
Cancer; Anticoagulants; Heparin
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The bi-directional association between cancer and the coagulation system has been known for almost 2 centuries. During the past 2 decades research has focused on the precise mechanisms through which cancer cells are able to induce a hypercoagulable state and how this leads to an environment favorable for cancer growth. Furthermore, the potential inhibitory effect of anticoagulant drugs on cancer progression has been explored. This article discusses these two aspects of the association.
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