Journal
HELVETICA CHIMICA ACTA
Volume 97, Issue 3, Pages 426-430Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/hlca.201300367
Keywords
Oxazoles; Phomopsis; Sesquiterpenes; Taxus chinensis; Fungi
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Funding
- National Natural Science Foundation of China [81203006]
- Science Foundation for the Youth Scholars of Guangdong Academy of Science [qnjj201009]
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A new sesquiterpene, eremophil-9-ene-11,12,13-triol (1), a new oxazole, 4-(2-hydroxyethyl)-5-methyloxazole (2), and the two known lactones, 5 '-hydroxyalternariol (3) and alternariol (4), were isolated from the extract of Phomopsis sp. A240, an endophytic fungus isolated from the bark of Taxus chinensis var. mairei. The structures of the isolated compounds were determined by analyses of their spectroscopic data, as well as by comparison with literature reports. The isolated compounds were evaluated for their cytotoxic and antioxidant activities.
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