Journal
HELVETICA CHIMICA ACTA
Volume 95, Issue 3, Pages 448-454Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/hlca.201100256
Keywords
1H-1; 2; 3-Triazoles; 1-aryl-; Click chemistry'; Multicomponent reactions
Categories
Funding
- Natural Science Foundation of China [30873153]
- Key Projects of Shanghai in Biomedicine [08431902700]
- Scientific Research Foundation of the State Education Ministry for the Returned Overseas Chinese Scholars
Ask authors/readers for more resources
The synthesis of monosubstituted 1-aryl-1H-1,2,3-triazoles was achieved in a one-pot reaction from arylboronic acids and prop-2-ynoic acid or calcium acetylide (=calcium carbide), respectively, as a source of acetylene, with yields ranging from moderate to excellent (Scheme 1, Table 2). The reaction conditions were successfully applied to arylboronic acids, including analogs with various functionalities. Unexpectedly, the 1,2,3-triazole moiety promoted a regioselective hydrodebromination (Scheme 2).
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available