4.3 Article

Three New Benzophenone Glucosides from the Leaves of Planchonella obovata

Journal

HELVETICA CHIMICA ACTA
Volume 93, Issue 3, Pages 522-529

Publisher

WILEY-BLACKWELL
DOI: 10.1002/hlca.200900264

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Funding

  1. National Science Council, Taiwan, R.O.C. [NSC 95-2320-B-002-033, NSC 96-2320-B-002-015]

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Chemical investigation of the EtOH extract of the leaves of Planchonella obovata resulted in the isolation of four benzophenone glucosides, 1-4. of which three, 2-4, are new chemical entities together with five known flavonol glycosides. Their structures were elucidated by spectroscopic analysis. Among the isolated compounds, iriflophenone 2-O-(2,6-di-O-galloyl)-beta-D-glucopyranoside (4) showed some activity (91.4 and 15.0% inhibition at 100 and 10 mu g/ml. resp.) against the alpha-glucosidase of Bacillus stearothermophilus.

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