Journal
HELVETICA CHIMICA ACTA
Volume 92, Issue 8, Pages 1586-1593Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/hlca.200900028
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Funding
- National Natural Science Foundation of China (NSFC) [20706012]
- National High Technology Research and Development Key Program of China [2007AA021506]
- Scientific Research Foundation for the Returned Overseas Chinese Scholars (Ministry of Personnel)
- Hubei Provincial Innovative Research Team in University [T200608]
- Hubei Provincial Natural Science Foundation for Innovative Research Twin
- Hubei Provincial International Cooperation Foundation for Scientific Research [2007CA012]
- Science and Technology Commission of Wuhan Municipality 'Chenguang Jihua' [20065004116-31]
- Scientific Research Key, Foundation from Hubei University of Technology [306.18002]
- Hubei Provincial Department of Education, China
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Three new lanostane triterpene acids, 3-O-acetylganoderic acid B (1), 8 beta,9 alpha-dihydroganoderic acid C (3), and 3-O-acetylganoderic acid K (4), as well as two new lanostane triterpene acid ethyl esters, ethyl 3-O-acetylganode rate B (2) and ethyl ganoderate J (5), were isolated and characterized from Ganoderma lucidum mycelia which was cultured by submerged fermentation method. Their structures were elucidated on the basis of spectroscopic methods. In addition, the identification of two known lanostane triterpene acid methyl esters, methyl O-acetyl ganoderate C and methyl 3,7,11,15,23-pentaoxolanost-8-en-26-oate were identified by comparison of the NMR data with those reported in the literature.
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