Article
Cardiac & Cardiovascular Systems
Mirae Lee, Alon Shechter, Donghee Han, Long-Co Nguyen, Min Sun Kim, Daniel S. Berman, Florian Rader, Robert J. Siegel
Summary: This study evaluated the morphologic progression of the left ventricle (LV) in apical hypertrophic cardiomyopathy (AHC) patients using serial echocardiograms. The results showed that about half of the patients had changes in LV morphology, with some patients experiencing further hypertrophic involvement and the development of apical pouches or aneurysms. The study also found that patients with more severe LV hypertrophy and apical involvement had higher rates of adverse clinical events.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Fabian Laumer, Davide Di Vece, Victoria L. Cammann, Michael Wuerdinger, Vanya Petkova, Maximilian Schoenberger, Alexander Schoenberger, Julien C. Mercier, David Niederseer, Burkhardt Seifert, Moritz Schwyzer, Rebekka Burkholz, Luca Corinzia, Anton S. Becker, Frank Scherff, Sofie Brouwers, Aju P. Pazhenkottil, Svetlana Dougoud, Michael Messerli, Felix C. Tanner, Thomas Fischer, Victoria Delgado, P. Christian Schulze, Christian Hauck, Lars S. Maier, Ha Nguyen, Sven Y. Surikow, John Horowitz, Kan Liu, Rodolfo Citro, Jeroen Bax, Frank Ruschitzka, Jelena-Rima Ghadri, Joachim M. Buhmann, Christian Templin
Summary: This cohort study established a real-time system for fully automated interpretation of echocardiogram videos and used machine learning to differentiate takotsubo syndrome (TTS) from acute myocardial infarction (AMI). The system achieved higher accuracy in echocardiography-based disease classification compared to cardiologists.
Article
Cardiac & Cardiovascular Systems
Mark Sherrid, Samuel Bernard, Nidhi Tripathi, Yash Patel, Vivek Modi, Leon Axel, Soheila Talebi, Brian B. Ghoshhajra, Danita Y. Sanborn, Muhamed Saric, Elizabeth Adlestein, Isabel Castro Alvarez, Yuhe Xia, Daniel G. Swistel, Daniele Massera, Michael A. Fifer, Bette Kim
Summary: This study investigated the frequency of mid-LV obstruction in apical aneurysms of hypertrophic cardiomyopathy (HCM). The results showed that 95% of patients with aneurysms had mid-LV obstruction. Further research is needed to explore the relationship between mid-LV obstruction and aneurysms.
JACC-CARDIOVASCULAR IMAGING
(2023)
Article
Cardiac & Cardiovascular Systems
John S. Dayco, Riyad Y. Kherallah, Josh Epstein, Oluwole Adegbala, Christina Reji, Karim Dirani, Carlos Oviedo, Luis Afonso
Summary: Standard echocardiographic indices of diastolic function have limited diagnostic value in patients with Takotsubo cardiomyopathy and are not as accurate as invasive measurements of left ventricular end-diastolic pressure and left ventricular pre-A wave diastolic pressure. Therefore, invasive measurements should be used for optimal risk stratification and management in these patients.
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
(2023)
Article
Cardiac & Cardiovascular Systems
Majd Al Deen Alhuarrat, Diego Barzallo, Jiyoung Seo, Ahmad Naser, Mohammad Rasoul Alhuarrat, Aurelia Minuti, Damianos G. Kokkinidis, Dimitrios Schizas
Summary: Perioperative takotsubo cardiomyopathy (pTCM) is a type of cardiomyopathy that occurs during surgery due to emotional and physiological stress. This study aimed to classify and understand the clinical features, management, and prognosis of noncardiac surgery pTCM. The analysis of 101 cases showed that pTCM commonly occurred during general surgery and transplant procedures, with a median age of 55 years. Hypertension and mood disorders were prevalent in these cases. Initial symptoms included STT-wave changes, arrhythmias, and hypotension. Mechanical circulatory support was required in some cases, and the all-cause in-hospital mortality rate was 6.9%.
AMERICAN JOURNAL OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Marie F. Borresen, Elisabeth Blixenkrone-Moller, Thilde O. Kock, Anne-Sophie Sillesen, R. Ottilia B. Vogg, Christian A. Pihl, Jakob B. Norsk, Niels G. Vejlstrup, Alex H. Christensen, Kasper K. Iversen, Henning Bundgaard, Anna Axelsson Raja
Summary: Left ventricular noncompaction (LVNC) is characterized by excessive trabeculations of the LV and may be associated with reduced systolic function or severe adverse outcomes. This study found a prevalence of 0.076% for LVNC in neonates and significant association with lower LV systolic function.
CIRCULATION-CARDIOVASCULAR IMAGING
(2022)
Review
Pharmacology & Pharmacy
Jaime Andres Pereanez, Johan Granados, Raquel Agudelo
Summary: This study investigated the relationship between Tako-tsubo cardiomyopathy (TTC) and exposure to animal venoms, toxins, or poisons. The findings suggest that most cases of TTC are triggered by venomous species such as snakes and insects. The study hypothesized that the release of catecholamines may be the mechanism behind this association. Further research is needed to explore other possible mechanisms in this field.
Review
Medicine, General & Internal
Jerzy Paluszkiewicz, Hendrik Milting, Marta Kaluzna-Oleksy, Malgorzata Pyda, Magdalena Janus, Hermann Koerperich, Misagh Piran
Summary: Left ventricular non-compaction (LVNC) refers to the excessive trabeculation and formation of a deep recess filled with blood in the left ventricle. Due to the lack of a standardized definition and criteria, it is difficult to accurately estimate the incidence of the disease, and overdiagnosis is a common issue. Non-compacted myocardium can be a disease representation, a variant of normal, or an adaptive phenomenon. This article covers different approaches to the incidence, pathogenesis, diagnostics, and treatment of LVNC, as well as recommendations for patient follow-up.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Respiratory System
Christos G. Mihos, Sofia A. Horvath, Rafle Fernandez, Esteban Escolar
Summary: This study investigates the long-term follow-up of left ventricular function and mechanics in ApHCM patients. The results show progressive impairment in GLS, GWI, and global constructive work over time. Atrial fibrillation and glomerular filtration rate are independently associated with decreased GLS and GWI. Global wasted work >186 mmHg% predicts composite complications.
JOURNAL OF THORACIC DISEASE
(2023)
Article
Cardiac & Cardiovascular Systems
Deacon Z. J. Lee, Raymond H. Chan, Mahdi Montazeri, Sara Hoss, Arnon Adler, Elsie T. Nguyen, Harry Rakowski
Summary: The study suggests that contrast echocardiography has high sensitivity for detecting LV apical aneurysms in patients with HCM. Compared with CMR and noncontrast echocardiography, contrast echocardiography showed higher sensitivity, providing an important reference for the evaluation and risk stratification of high-risk HCM patients.
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
(2021)
Article
Cardiac & Cardiovascular Systems
Mark Sherrid, Daniel G. Swistel, Iacopo Olivotto, Maurizio Pieroni, Omar Wever-Pinzon, Katherine Riedy, Richard G. Bach, Mustafa Husaini, Sharon Cresci, Alex Reyentovich, Daniele Massera, Martin S. Maron, Barry J. Maron, Bette Kim
Summary: Patients with obstructive hypertrophic cardiomyopathy who develop cardiogenic shock and left ventricular ballooning present with distinctive anatomical and physiological features, including LV outflow obstruction. Treatment involves targeted pharmacotherapy, mechanical circulatory support, and, if necessary, myectomy for refractory shock.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Review
Cardiac & Cardiovascular Systems
Lorraine Lok-Wing Chiang, Shek Long Tsang, Jing Xian Lee, Mengqi Gong, Tong Liu, Gary Tse, Dong Chang, Ishan Lakhani, Ka Hou Christien Li
Summary: Reduced LVEF, both as a categorical and continuous variable, is associated with increased mortality risk in Takotsubo cardiomyopathy patients. However, the presence of apical ballooning did not show a significant link with mortality risk.
HEART FAILURE REVIEWS
(2021)
Article
Medicine, General & Internal
Hamada Alsheikh, Nour Shaheen, Wageih Saber, Mostafa Meshref, Yara Amro, Ahmed Shaheen, Mahmoud Galal Ahmed, Sarya Swed
Summary: A patient with high-risk myocardial infarction was retroactively diagnosed with TCM after normal epicardial coronaries were revealed in coronary angiography. The patient underwent surgical repair of VSR and had a good recovery.
Review
Cardiac & Cardiovascular Systems
Rocco Antonio Montone, Giulia La Vecchia, Marco Giuseppe Del Buono, Antonio Abbate, Tommaso Sanna, Daniela Pedicino, Giampaolo Niccoli, Massimo Antonelli, Filippo Crea
Summary: This review article provides an overview of the acute clinical manifestations of patients with Takotsubo syndrome (TTS), highlighting predictors of worse short-term outcomes and challenges in the management of TTS-related complications in the acute care setting.
CURRENT PROBLEMS IN CARDIOLOGY
(2022)
Review
Medicine, General & Internal
Emanuele Monda, Marta Rubino, Giuseppe Palmiero, Federica Verrillo, Michele Lioncino, Gaetano Diana, Annapaola Cirillo, Adelaide Fusco, Francesca Dongiglio, Martina Caiazza, Ippolita Altobelli, Alfredo Mauriello, Natale Guarnaccia, Alessandra Scatteia, Arturo Cesaro, Giuseppe Pacileo, Berardo Sarubbi, Giulia Frisso, Barbara Bauce, Antonello D'Andrea, Santo Dellegrottaglie, Maria Giovanna Russo, Paolo Calabro, Giuseppe Limongelli
Summary: Arrhythmogenic cardiomyopathy (ACM) is a broad term for myocardial diseases characterized by progressive fibrotic or fibrofatty replacement, which leads to ventricular tachyarrhythmias and ventricular dysfunction. Arrhythmogenic left ventricular cardiomyopathy (ALVC) is a specific subtype that exclusively affects the left ventricle. Diagnosis of ALVC requires a combination of family history, clinical, electrocardiographic, and imaging features, with genetic testing for confirmation. Multimodality imaging techniques, such as echocardiography, cardiac magnetic resonance, and cardiac nuclear imaging, are essential for diagnosis, differential diagnosis, risk stratification, and management of ALVC.
JOURNAL OF CLINICAL MEDICINE
(2023)