A systematic review and meta-analysis of genotype–phenotype associations in patients with hypertrophic cardiomyopathy caused by sarcomeric protein mutations

New population-based exome data are questioning the pathogenicity of previously cardiomyopathy-associated genetic variants

(2013) Charlotte Andreasen et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Genetic complexity in hypertrophic cardiomyopathy revealed by high-throughput sequencing

(2013) Luis R Lopes et al.   JOURNAL OF MEDICAL GENETICS

Multiple gene mutations, not the type of mutation, are the modifier of left ventricle hypertrophy in patients with hypertrophic cardiomyopathy

(2013) Yubao Zou et al.   MOLECULAR BIOLOGY REPORTS

Burden of Rare Sarcomere Gene Variants in the Framingham and Jackson Heart Study Cohorts

(2012) Alexander G. Bick et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Cardiac Myosin Binding Protein-C Mutations in Families With Hypertrophic Cardiomyopathy

(2012) Stephen P. Page et al.   Circulation-Cardiovascular Genetics

Cardiac Structural and Sarcomere Genes Associated With Cardiomyopathy Exhibit Marked Intolerance of Genetic Variation

(2012) Stephen Pan et al.   Circulation-Cardiovascular Genetics

Population-Based Variation in Cardiomyopathy Genes

(2012) Jessica R. Golbus et al.   Circulation-Cardiovascular Genetics

Toronto Hypertrophic Cardiomyopathy Genotype Score for Prediction of a Positive Genotype in Hypertrophic Cardiomyopathy

(2012) Christiane Gruner et al.   Circulation-Cardiovascular Genetics

Genetics of Hypertrophic Cardiomyopathy After 20 Years

(2012) Barry J. Maron et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Myofilament Protein Gene Mutation Screening and Outcome of Patients With Hypertrophic Cardiomyopathy

(2012) Iacopo Olivotto et al.   MAYO CLINIC PROCEEDINGS

2011 ACCF/AHA Guideline for the Diagnosis and Treatment of Hypertrophic Cardiomyopathy: Executive Summary

(2011) et al.   CIRCULATION

Sarcomere Protein Gene Mutations in Patients With Apical Hypertrophic Cardiomyopathy

(2011) Christiane Gruner et al.   Circulation-Cardiovascular Genetics

Long-Term Outcomes in Hypertrophic Cardiomyopathy Caused by Mutations in the Cardiac Troponin T Gene

(2011) Ferdinando Pasquale et al.   Circulation-Cardiovascular Genetics

Novel correlations between the genotype and the phenotype of hypertrophic and dilated cardiomyopathy: results from the German Competence Network Heart Failure

(2011) Stephan Waldmüller et al.   EUROPEAN JOURNAL OF HEART FAILURE

Genetic basis of end-stage hypertrophic cardiomyopathy

(2011) Pablo Garcia-Pavia et al.   EUROPEAN JOURNAL OF HEART FAILURE

Microvascular Function Is Selectively Impaired in Patients With Hypertrophic Cardiomyopathy and Sarcomere Myofilament Gene Mutations

(2011) Iacopo Olivotto et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Inherited Cardiomyopathies

(2011) Hugh Watkins et al.   NEW ENGLAND JOURNAL OF MEDICINE

Espectro mutacional de los genes sarcoméricos MYH7, MYBPC3, TNNT2, TNNI3 y TPM1 en pacientes con miocardiopatía hipertrófica

(2011) Mónica García-Castro et al.   REVISTA ESPANOLA DE CARDIOLOGIA

Mutación en homocigosis en el gen MYBPC3 asociada a fenotipos severos y alto riesgo de muerte súbita en una familia con miocardiopatía hipertrófica

(2011) Martín F. Ortiz et al.   REVISTA ESPANOLA DE CARDIOLOGIA

Screening mutations in myosin binding protein C3 gene in a cohort of patients with Hypertrophic Cardiomyopathy

(2010) María Isabel Rodríguez-García et al.   BMC Medical Genetics

Mutation Type Is Not Clinically Useful in Predicting Prognosis in Hypertrophic Cardiomyopathy

(2010) Andrew P. Landstrom et al.   CIRCULATION

Prevalence and spectrum of mutations in a cohort of 192 unrelated patients with hypertrophic cardiomyopathy

(2010) Gilles Millat et al.   European Journal of Medical Genetics

Clinical Features and Outcome of Hypertrophic Cardiomyopathy Associated With Triple Sarcomere Protein Gene Mutations

(2010) Francesca Girolami et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Myocardial Fibrosis as an Early Manifestation of Hypertrophic Cardiomyopathy

(2010) Carolyn Y. Ho et al.   NEW ENGLAND JOURNAL OF MEDICINE

Histologic characterization of hypertrophic cardiomyopathy with and without myofilament mutations

(2009) Christopher J. McLeod et al.   AMERICAN HEART JOURNAL

The yield of risk stratification for sudden cardiac death in hypertrophic cardiomyopathy myosin-binding protein C gene mutation carriers: focus on predictive screening

(2009) Imke Christiaans et al.   EUROPEAN HEART JOURNAL

Abnormal blood pressure response to exercise occurs more frequently in hypertrophic cardiomyopathy patients with the R92W troponin T mutation than in those with myosin mutations

(2009) Marshall Heradien et al.   HEART RHYTHM

Diagnostic, Prognostic, and Therapeutic Implications of Genetic Testing for Hypertrophic Cardiomyopathy

(2009) J. Martijn Bos et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Myocardial fibrosis in patients with symptomatic obstructive hypertrophic cardiomyopathy: correlation with echocardiographic measurements, sarcomeric genotypes, and pro-left ventricular hypertrophy polymorphisms involving the renin-angiotensin-aldosterone system

(2008) Lori A. Blauwet et al.   CARDIOVASCULAR PATHOLOGY

Worse Prognosis with Gene Mutations of Beta-myosin Heavy Chain than Myosin-Binding Protein C in Chinese Patients with Hypertrophic Cardiomyopathy

(2008) Rutai Hui et al.   CLINICAL CARDIOLOGY

Diagnostic yield, interpretation, and clinical utility of mutation screening of sarcomere encoding genes in Danish hypertrophic cardiomyopathy patients and relatives

(2008) Paal Skytt Andersen et al.   HUMAN MUTATION

Hypertrophic cardiomyopathy: the genetic determinants of clinical disease expression

(2008) Andre Keren et al.   Nature clinical practice. Cardiovascular medicine