Article
Cardiac & Cardiovascular Systems
Andreas Rueck, Won-Keun Kim, Mohamed Abdel-Wahab, Holger Thiele, Tanja K. Rudolph, Alexander Wolf, Jan Martin Wambach, Ole De Backer, Lars Sondergaard, Christian Hengstenberg, Mika Laine, Hirokazu Miyashita, Henrik Bjursten, Matthias Goetberg, Costanza Pellegrini, Stefan Toggweiler, Joanna J. Wykrzykowska, Osama Soliman, Nawzad Saleh, Christopher U. Meduri
Summary: This study aimed to evaluate the safety and efficacy of ACURATE neo2 in transcatheter aortic valve implantation in Europe. The results showed favorable postoperative hemodynamics and clinical outcomes, as well as a low rate of postoperative pacemaker implantation.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Cardiac & Cardiovascular Systems
Kerstin Piayda, Timm Bauer, Andreas Beckmann, Raffi Bekeredjian, Sabine Bleiziffer, Stephan Ensminger, Christian Frerker, Helge Moellmann, Thomas Walther, Uemniye Balaban, Eva Herrmann, Christian Hamm, Friedhelm Beyersdorf, Artur Lichtenberg, Tobias Zeus, Arash Mehdiani
Summary: Patients with large and extra-large aortic annulus diameters who underwent TAVI have comparable 30-day mortality. However, beyond the recommended annulus range, there is a higher risk for longer procedure duration, vascular complications, and permanent pacemaker implantation.
AMERICAN JOURNAL OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Eduardo Flores-Umanzor, Jason Nogic, Pedro Cepas-Guillen, Sebastien Hascoet, Piotr Pysz, Jose Antonio Baz, Ignacio Cruz-Gonzalez, Ignacio Amat-Santos, Pablo Antunez-Muinos, Jose Carlos Gonzalez, Valeriano Ruiz-Quevedo, Rodrigo Estevez-Loureiro, Benoit Gerardin, Xavier Millan, Marcel Santalo-Corcoy, Ander Regueiro, Reda Ibrahim, Dabit Arzamendi, Eustaquio Maria Onorato, Josep Rodes-Cabau, Eric Horlick, Patrick A. Calvert, Xavier Freixa
Summary: This study presents a large multicentre international experience, demonstrating that percutaneous closure of para-valvular leak (PVL) after transcatheter aortic valve implantation (TAVI) is a feasible and safe option. Successful reduction of PVL to mild or less may be associated with acute and long-lasting improvements in clinical outcomes.
Article
Cardiac & Cardiovascular Systems
Gloria Faerber, Sabine Bleiziffer, Torsten Doenst, Dimitra Bon, Andreas Boening, Helge Weiler, Eva Herrmann, Christian Frerker, Andreas Beckmann, Helge Moellmann, Stephan Ensminger, Raffi Bekeredjian, Thomas Walther, Wolfgang Harringer, Hugo A. Katus, Christian W. Hamm, Friedhelm Beyersdorf, Timm Bauer, Stephan Fichtlscherer
Summary: Chronic dialysis patients with AS undergoing TAVI or SAVR had similar 1-year mortality rates, with better survival at 30 days for TAVI patients. TAVI may improve peri-procedural outcomes, although TAVI patients required more pacemaker implantation and showed more aortic regurgitation, while SAVR patients required more blood transfusions and had longer hospital stays.
CLINICAL RESEARCH IN CARDIOLOGY
(2021)
Article
Medicine, General & Internal
Taishi Okuno, Caglayan Demirel, Daijiro Tomii, Gabor Erdoes, Dik Heg, Jonas Lanz, Fabien Praz, Rainer Zbinden, David Reineke, Lorenz Raber, Stefan Stortecky, Stephan Windecker, Thomas Pilgrim
Summary: This study aimed to evaluate the risk of noncardiac surgery after TAVI. The results suggest that noncardiac surgery can be performed early after successful TAVI, and device performance may impact the risk of adverse outcomes after surgery.
Article
Cardiac & Cardiovascular Systems
Uri Landes, Aviram Hochstadt, Lisa Manevich, John G. Webb, Janarthanan Sathananthan, Horst Sievert, Kerstin Piayda, Martin B. Leon, Tamim M. Nazif, David Hildick-Smith, Chris Pavitt, Holger Thiele, Mohamed Abdel-Wahab, Nicolas M. Van Mieghem, Rik Adrichem, Lars Sondergaard, Ole De Backer, Raj R. Makkar, Ofir Koren, Thomas Pilgrim, Taishi Okuno, Ran Kornowski, Pablo Codner, Ariel Finkelstein, Itamar Loewenstein, Israel Barbash, Amir Sharon, Federico De Marco, Matteo Montorfano, Nicola Buzzatti, Azeem Latib, Andrea Scotti, Won-Keun Kim, Christian Hamm, Luis Nombela Franco, Antonio Mangieri, Wolfgang H. Schoels, Marco Barbanti, Matjaz Bunc, Myriama Akodad, Ronen Rubinshtein, Haim Danenberg
Summary: This study investigated the effect of transcatheter interventions to treat paravalvular regurgitation (PVR) after transcatheter aortic valve implantation (TAVI). The results showed that patients with successful reduction of PVR had better prognosis, but further investigation is needed to determine the selection of patients and the optimal treatment modality for PVR.
EUROPEAN HEART JOURNAL
(2023)
Review
Medicine, General & Internal
Sarah Mauler-Wittwer, Stephane Noble
Summary: Practice is important in complex interventions, as there is a strong relationship between high volume and better outcomes. The complexity of the procedure affects the volume-outcome relationship. Failure to rescue is a factor leading to higher mortality rates after complex surgery. High-volume centers offer a better safety net with improved structure and protocols, while low-volume operators have better results in high-volume centers.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Medicine, General & Internal
Ana Paula Tagliari, Rodrigo Petersen Saadi, Eduardo Keller Saadi
Summary: TAVI is a well-established procedure for treating aortic stenosis, but using it for high-risk patients with pure native aortic regurgitation is considered an off-label intervention, especially when the aortic annulus dimensions are beyond the recommended range.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Evaldas Girdauskas, Johannes Petersen, Uemniye Balaban, Eva Herrmann, Timm Bauer, Andreas Beckmann, Raffi Bekeredjian, Stephan Ensminger, Christian Frerker, Helge Moellmann, Thomas Walther, Sabine Bleiziffer
Summary: AV repair/AV-sparing root surgery is an effective strategy for treating young patients with aortic regurgitation and/or aortic root aneurysm. This study analyzed real-world data from the German Aortic Valve Registry and found that the surgical procedure resulted in satisfactory clinical outcomes, including high survival rates and freedom from cardiac adverse events at one year. Additionally, the specific surgical technique used did not significantly impact the outcomes.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Uri Landes, Olga Morelli, Haim Danenberg, Janarthanan Sathananthan, Ole De Backer, Lars Sondergaard, Mohamed Abdel-Wahab, Sung-Han Yoon, Raj R. Makkar, Holger Thiele, Won-Keun Kim, Christian Hamm, Mayra Guerrero, Josep Rodes-Cabau, Taishi Okuno, Thomas Pilgrim, Antonio Mangieri, Nicolas M. Van Mieghem, Didier Tchetche, Wolfgang H. Schoels, Marco Barbanti, Jan-Malte Sinning, Alfonso Ielasi, Giuseppe Tarantini, Federico De Marco, Ariel Finkelstein, Horst Sievert, Martin Andreas, Azeem Latib, Rebecca Godfrey, David Hildick-Smith, Lisa Manevich, Ran Kornowski, Tamim M. Nazif, Martin B. Leon, John G. Webb
Summary: The study focused on the efficacy of redo-TAVI in reducing para-valvular regurgitation after transcatheter aortic valve implantation. Results showed that redo-TAVI was effective in reducing regurgitation and improving procedural success rates for PVR patients. Further investigation is needed for patient selection in PVR therapies.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2022)
Article
Medicine, General & Internal
Juqian Zhang, Arnaud Bisson, Jad Boumhidi, Julien Herbert, Christophe Saint Etienne, Anne Bernard, Gregory Y. H. Lip, Laurent Fauchier
Summary: Baseline MR and TR were associated with increased all-cause and cardiovascular mortality post-TAVI, however, neither of them was an independent predictor for all-cause or cardiovascular mortality.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Jun Shi, Lai Wei, Yucheng Chen, Xu Wang, Jian Ye, Chaoyi Qin, Lulu Liu, Hong Qian, Chunsheng Wang, Yingqiang Guo
Summary: The study showed good midterm outcomes of transcatheter aortic valve implantation with the J-Valve system in treating patients with aortic stenosis or pure aortic insufficiency, suggesting it as a promising alternative therapy for high-risk patients.
ANNALS OF THORACIC SURGERY
(2021)
Review
Cardiac & Cardiovascular Systems
Sahoor A. Khan, Suzanne J. Baron
Summary: Approximately 2% of people aged 70 to 83 in the United States suffer from moderate or severe aortic regurgitation, with up to 8% of eligible patients not receiving treatment. While transcatheter devices specifically for AR are still in development, off-label use of current TAVI devices has shown acceptable safety and efficacy for severe AR treatment in inoperable patients.
Article
Cardiac & Cardiovascular Systems
Christian Nitsche, Matthias Koschutnik, Carolina Dona, David Mutschlechner, Kseniya Halavina, Georg Spinka, Varius Dannenberg, Katharina Mascherbauer, Leah Sinnhuber, Andreas Kammerlander, Max Paul Winter, Philipp Bartko, Georg Goliasch, Philippe Pibarot, Christian Hengstenberg, Julia Mascherbauer
Summary: This study aimed to assess the incidence, correlates, causes, and outcome of early to mid-term bioprosthetic valve dysfunction (BVD) after transcatheter aortic valve implantation (TAVI). The study found that BVD occurred at the same rate across different life expectancies and was associated with increased mortality in patients with shorter life expectancies.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2023)
Article
Medicine, General & Internal
Thorald Stolte, Jasper Boeddinghaus, Giampiero Allegra, Gregor Leibundgut, Oliver Reuthebuch, Christoph Kaiser, Christian Mueller, Thomas Nestelberger
Summary: This study highlights the increasing trend of valve-in-valve procedures for patients with aortic stenosis over the last decade. The results show that these interventions are feasible and result in lasting improvements in mean aortic valve gradients. There were no differences in technical and device successes or event-free survival between TAVR-in-SAVR and TAVR-in-TAVR.
JOURNAL OF CLINICAL MEDICINE
(2023)