Review
Chemistry, Analytical
Wei Wei, Yaping Wang, Zhaoxun Wang, Xuexin Duan
Summary: Acoustofluidics, a branch of microfluidics, has developed rapidly in recent decades, with applications in various biomedical and bioanalytical fields. The manipulation of liquids and bioparticles using acoustic pressure and acoustic streaming effects is the main focus of acoustofluidics. While the use of acoustic radiation force has been extensively studied, the recent development of new piezoelectric devices has sparked interest in particle manipulations using drag force induced by acoustic streaming. This review article summarizes the recent advancements in microscale acoustic streaming, including high-frequency transducer-induced high-speed streaming, confinement and programed streaming, and acoustic streaming tweezers, which combine acoustic radiation force and drag force to overcome size limitations in conventional acoustic manipulations. The article also provides a brief overview of acoustic streaming theory, its generation, applications, and key issues in the field. Lastly, the future prospects of micro acoustic streaming in bioanalytical and biomedical applications are discussed.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Article
Acoustics
Mushtaq Ali, Jinsoo Park
Summary: In droplet-based microfluidic platforms, there is increasing demand for precise separation of microscale droplets of different chemical composition. Most existing techniques focus on separating droplets of the same kind, while there is less effort on separating uniform-sized droplets of different chemical composition. This study proposes an acoustofluidic method using ultrasonic surface acoustic wave (SAW)-induced acoustic radiation force (ARF) to simultaneously separate uniform-sized droplets of different acoustic impedance. The experimental results show that the proposed method provides a label-free and detection-free approach for on-chip, precise separation of multiple kinds of droplets in microfluidic applications.
ULTRASONICS SONOCHEMISTRY
(2023)
Article
Biochemical Research Methods
Robert Weser, Zhichao Deng, Vijay V. Kondalkar, Alexandre N. Darinskii, Christian Cierpka, Hagen Schmidt, Joerg Koenig
Summary: Acoustic tweezers provide a noninvasive, contactless method for precise manipulation of micro objects, including biological cells. This study reveals the correlation between acoustic fields, acoustophoretic motion and heating effects, and demonstrates three-dimensional particle patterning and rapid heating.
Article
Engineering, Mechanical
Hua-Yang Chen, Zhen-Hui Qin, Sheng-Nan Liang, Xin Li, Si-Yuan Yu, Yan-Feng Chen
Summary: A gradient-index seismic metamaterial based on a surface acoustic PnC is proposed to provide omnidirectional protection against ultra-broadband seismic Rayleigh waves.
EXTREME MECHANICS LETTERS
(2023)
Article
Mathematics, Interdisciplinary Applications
H. Alinejad
Summary: In this paper, the non-linear propagation of dust ion-acoustic waves in a complex dusty plasma is fully analyzed using bifurcation techniques and numerical simulations. A dynamical system capturing the main features of traveling wave solutions and transition between nonlinear modes is derived. The study reveals the existence domains of stability regions for different ranges of electron nonextensivity and dust concentration. The motion dynamics of low-frequency dust ion-acoustic traveling waves undergoes a transcritical bifurcation at critical points of nonextensivity parameter and dust concentration, resulting in a switch of stability. A new kind of solitary structure characterized by transcritical bifurcation parameters with half-stable equilibrium points is observed. The effects of nonextensive parameter and dust polarity on the transition between nonlinear traveling waves are investigated.
CHAOS SOLITONS & FRACTALS
(2022)
Article
Engineering, Multidisciplinary
U. M. Abdelsalam
Summary: A mathematical model was developed to study plasma systems in space where electrons follow non-extensive distribution and ions and dust particles are charged. The study found that the magnetic field plays an important role in the nonlinear propagation of dense astrophysical objects, along with charged ions and dust particles. Numerical analysis showed that the magnetic field is equally important in this nonlinear process.
AIN SHAMS ENGINEERING JOURNAL
(2021)
Article
Chemistry, Analytical
Adam L. Hollerbach, Yehia M. Ibrahim, Vanessa Meras, Randolph V. Norheim, Adam P. Huntley, Gordon A. Anderson, Thomas O. Metz, Robert G. Ewing, Richard D. Smith
Summary: High-resolution ion mobility spectrometry-mass spectrometry (HR-IMS-MS) instruments have significantly enhanced the characterization of complex biological mixtures. By using a dual-gated ion injection approach, we coupled an 11 m path length SLIM module to a Q-Exactive Plus Orbitrap MS platform, enabling simultaneous SLIM separation, high-resolution Orbitrap mass analysis, and high-energy collision-induced dissociation (HCD). The SLIM-Orbitrap platform was characterized using standard phosphazene cations, standard peptides, and complex lipid mixtures, demonstrating its capability for peptide identification and isobaric lipid separations.
ANALYTICAL CHEMISTRY
(2023)
Article
Multidisciplinary Sciences
Benoit Tallon, Philippe Roux, Guillaume Matte, Jean Guillard, John H. Page, Sergey E. Skipetrov
Summary: The study observed a significant slowdown in acoustic wave transport in dense fish shoals in open-sea fish cages, with the energy transport velocity found to be about 10 times smaller than the speed of sound in water, indicating a slow transport of ultrasonic waves. While the swim bladder of the fish plays an important role in wave scattering, other organs must also be considered to explain the ultra-low energy transport velocities observed.
SCIENTIFIC REPORTS
(2021)
Article
Chemistry, Analytical
Ilaria Di Luch, Maddalena Ferrario, Davide Fumagalli, Michele Carboni, Mario Martinelli
Summary: This study presents a coherent optical fiber sensor with adequate sensitivity for detecting the acoustic emission during the propagation of a crack in a ferrous material. The sensor is compared to commercially available AE piezo-transducers sensors in terms of SNR and detectable AE energy levels, showing it to be an effective and advantageous alternative for sensing and monitoring fatigue damage in structural applications.
Article
Computer Science, Artificial Intelligence
Juan-Gerardo Avalos, Giovanny Sanchez, Carlos Trejo, Luis Garcia, Eduardo Pichardo, Angel Vazquez, Esteban Anides, Juan-Carlos Sanchez, Hector Perez
Summary: This work presents a high-performance and ultra-compact spike-based hardware architecture for acoustic echo cancellation, addressing factors such as reducing computational costs and improving processing speeds through new adaptive filters and compact high-precision neural multipliers. This hardware implementation technique shows potential for easy integration into portable devices for real-world acoustic echo cancellation scenarios.
APPLIED SOFT COMPUTING
(2021)
Article
Engineering, Electrical & Electronic
Jun Long Han, Hong Hu, Qing Yun Huang, Yu Lin Lei
Summary: In this study, an acoustofluidic platform based on standing surface acoustic waves (SSAWs) was established to analyze the influence of droplet contact angle on particle separation. Experimental results demonstrated the importance of reducing the contact angle for achieving better particle separation efficiency.
SENSORS AND ACTUATORS A-PHYSICAL
(2021)
Review
Nanoscience & Nanotechnology
Matteo Agostini, Marco Cecchini
Summary: Surface acoustic waves (SAWs) are an advanced technology used in microfluidics and biosensing, with high sensitivity and fluid manipulation capabilities, suitable for LoC applications. By using high-frequency SAWs, device miniaturization and high-performance manipulation of biological liquids are achieved.
Article
Acoustics
Yoav Vered, Izhak Bucher
Summary: This paper presents a method for measuring acoustic properties in fluids using wavetubes, and proposes a new approach to manipulate the boundary impedance of the tube at will using loudspeakers. By estimating a parametric reduced-order model in real-time and implementing nonlinear control algorithms, modal traveling wave ratio control can be achieved, ensuring smooth and convergent control of the system.
JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA
(2021)
Article
Engineering, Mechanical
Yoav Vered, Izhak Bucher
Summary: This paper introduces a method that expands the concept of traveling wave ratio, which decomposes waves through several schemes and proposes an optimal balance between increasing model order and maintaining low uncertainty. Experimental results demonstrate the importance of including additional propagating modes in nondestructive testing and waveguide experiments, as well as the capability of using the recursive multichannel least-mean-squares method to control wave propagation patterns.
MECHANICAL SYSTEMS AND SIGNAL PROCESSING
(2021)
Article
Materials Science, Multidisciplinary
Carolin Drees, Simon Hoving, Wolfgang Vautz, Joachim Franzke, Sebastian Brandt
Summary: This article introduces the process and results of manufacturing an ion mobility spectrometer using 3D printing technology, demonstrating the potential of 3D printing for design optimization and rapid prototyping of analytical instrumentation.
Article
Physics, Applied
B. J. Ash, A. R. Rezk, L. Y. Yeo, G. R. Nash
Summary: The research demonstrates how arrays of annular hole resonators can confine surface acoustic waves to regions much smaller than their wavelength, opening up new possibilities for applications in signal processing, sensing, and microfluidics.
APPLIED PHYSICS LETTERS
(2021)
Article
Chemistry, Multidisciplinary
Lizebona August Ambattu, Amy Gelmi, Leslie Y. Yeo
Summary: Mechanostimulation using high frequency mechanical cues has been shown to induce differentiation of human mesenchymal stem cells towards an osteoblast lineage. This discovery has significant implications for stem cell differentiation technologies in regenerative medicine.
Article
Chemistry, Physical
Yemima Ehrnst, Heba Ahmed, Robert Komljenovic, Emily Massahud, Nick A. Shepelin, Peter C. Sherrell, Amanda Ellis, Amgad R. Rezk, Leslie Y. Yeo
Summary: In this study, we reported an acoustomicrofluidic method for the rapid synthesis of homogeneous MOF/graphene oxide (GO) planar heterostructures without the need for additives. The method successfully templated quasi-2D MOF crystals onto GO sheets, forming stacked layers. Compared to the traditional 3D copper-based MOF, the quasi-2D MOFs have exposed Cu sites that facilitate efficient coordination with GO. The freestanding membranes constructed with this structure exhibit excellent reduction resistance and integrity of the MOF crystal structure.
JOURNAL OF MATERIALS CHEMISTRY A
(2022)
Article
Nanoscience & Nanotechnology
Nicholas S. L. Chew, Kiing S. Wong, Wei S. Chang, Chien W. Ooi, Leslie Y. Yeo, Ming K. Tan
Summary: Plasma treatment is an efficient chemical-free disinfection method. By combining nanoscale technologies, we have achieved nanoscale plasma activation and surface spraying in a small and lightweight device. This device shows significant improvements in plasma activation and disinfection time compared to previous methods.
MICROSYSTEMS & NANOENGINEERING
(2022)
Article
Engineering, Chemical
James Van Strien, Phred Petersen, Petros Lappas, Leslie Yeo, Amgad Rezk, Sara Vahaji, Kiao Inthavong
Summary: In addition to topical delivery, nasal sprays provide an alternative drug administration route that avoids the need for painful and invasive techniques. However, conflicting studies on the efficacy of nasal drug delivery exist. This study characterizes different types of nasal sprays to provide benchmark experimental data for computational models, aiming to improve future studies on nasal spray drug delivery in the nasal cavity.
JOURNAL OF AEROSOL SCIENCE
(2022)
Article
Engineering, Biomedical
Lizebona August Ambattu, Callum Knight, Keng-hui Lin, Amy Gelmi, Leslie Y. Yeo
Summary: This study investigates the effects of short-duration mechanostimulation on endothelial junction stability and barrier capacity. The study found that the integrity of the endothelial barrier can not only recover but also enhance considerably after transient disruption, thanks to the role of calcium and cAMP signaling. Such enhancement in barrier capacity is useful for developing in vitro models that resemble in vivo conditions.
Article
Multidisciplinary Sciences
Heba Ahmed, Hossein Alijani, Ahmed El-Ghazaly, Joseph Halim, Billy J. Murdoch, Yemima Ehrnst, Emily Massahud, Amgad R. Rezk, Johanna Rosen, Leslie Y. Yeo
Summary: MXenes possess superior electrical properties, but their practical adoption is hindered by oxidative susceptibility. This study demonstrates that subjecting oxidized MXene films to nanoscale electromechanical vibration can remove the oxide layer and restore their electrochemical performance close to the original state. These promising results offer the potential for MXene rejuvenation and improve its practical application.
NATURE COMMUNICATIONS
(2023)
Article
Chemistry, Physical
Yemima Ehrnst, Peter C. Sherrell, Amgad R. Rezk, Leslie Y. Yeo
Summary: A novel strategy using high-frequency hybrid sound waves to enhance hydrogen evolution reactions in neutral electrolytes is presented. By modifying the coordination state of water molecules and utilizing other synergistic effects, the technology achieves a significant reduction in overpotential, increase in current density, and energy saving.
ADVANCED ENERGY MATERIALS
(2023)
Article
Chemistry, Physical
Emily Massahud, Heba Ahmed, Ravichandar Babarao, Yemima Ehrnst, Hossein Alijani, Connie Darmanin, Billy J. Murdoch, Amgad R. Rezk, Leslie Y. Yeo
Summary: This study demonstrates that defects can be engineered into ZIF-8 crystals by coupling high frequency hybrid surface and bulk acoustic waves and applying acoustic radiation pressure and hydrodynamic stresses. The diffusion of guest molecules into the material's pores is enhanced, leading to expansion of the pore framework and the creation of dangling-linker and missing-linker defects. The technology is also shown to be practical for solvent-assisted ligand exchange without compromising the framework porosity or crystal structure.
Article
Chemistry, Multidisciplinary
Emily Massahud, Heba Ahmed, Lizebona A. Ambattu, Amgad R. Rezk, Leslie Y. Yeo
Summary: This study reports a rapid and simple one-pot aerosol-based method for synthesizing metal-organic frameworks (MOFs) and encapsulating enzymes. The method increases the porosity of MOFs and modifies the structure of enzymes, resulting in higher loading efficiency, enhanced enzyme activity, and stronger protective effect against high temperature and organic solvents. Compared to traditional methods, the biocomposite material obtained in this study demonstrates improved enzyme activity and protection.
MATERIALS TODAY CHEMISTRY
(2023)
Article
Mechanics
Jasmine O. Castro, Melati Abdul S. Halim, Lizebona A. Ambattu, Amgad R. Rezk, Ranganathan Prabhakar, Reza Nosrati, Leslie Y. Yeo
Summary: We demonstrate that the time required for a liquid bridge filament to thin and break up under elastocapillary stresses can be used as a proxy for quantifying the motile sperm concentration. By comparing the results with OpenCASA measurements, our platform is capable of predicting sperm quality with high accuracy, sensitivity, and specificity. These findings highlight the potential of our platform as a rapid, low-cost, and portable alternative for veterinary male bovine fertility assessment.
Review
Biophysics
Lizebona August Ambattu, Leslie Y. Yeo
Summary: All cells have the ability to respond to mechanical stimuli through their internal machinery. This review discusses the mechanotransductive processes associated with acoustic stimuli and the applications that arise from the cellular responses, particularly in regenerative therapeutics.
BIOPHYSICS REVIEWS
(2023)
