Article
Cardiac & Cardiovascular Systems
Amil. M. M. Shah, Brian Claggett, Narayana Prasad, Guichu Li, Mayra Volquez, Karola Jering, Maja Cikes, Attila Kovacs, Wilfried Mullens, Jose C. Nicolau, Lars Kober, Peter Van der Meer, Pardeep. S. S. Jhund, Ghionul Ibram, Martin Lefkowitz, Yinong Zhou, Scott. D. D. Solomon, Marc A. Pfeffer
Summary: This study compared the effects of sacubitril/valsartan and ramipril on left ventricular function and adverse remodeling after acute myocardial infarction (AMI). The results showed that patients randomized to sacubitril/valsartan had better improvements in filling pressure, left ventricular volume changes, and other aspects compared to those randomized to ramipril.
Article
Medicine, General & Internal
Harish Sharma, Mengshi Yuan, Iqra Shakeel, James Hodson, Ashwin Radhakrishnan, Samuel Brown, John May, Kieran O'Connor, Nawal Zia, Sagar N. Doshi, Sandeep S. Hothi, Jonathan N. Townend, Saul G. Myerson, Peter F. Ludman, Richard P. Steeds, M. Adnan Nadir
Summary: This study aimed to examine the change in mitral regurgitation (MR) severity and its impact on long-term outcomes following acute myocardial infarction (MI). The results showed that approximately one-third of the patients had improved MR severity at the first follow-up transthoracic echocardiography (TTE), while 10% had increased severity. Older age and lower creatinine clearance were predictors of worsening MR. Patients with persistent or worsening MR had worse clinical outcomes compared to those with improving MR.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Filipa X. Valente, Jose Gavara, Laura Gutierrez, Cesar Rios-Navarro, Pau Rello, Manel Maymi, Ruben Fernandez-Galera, Jose V. Monmeneu, Augusto Sao-Aviles, Maria P. Lopez-Lereu, M. Teresa Gonzalez-Alujas, David Moratal, Hug Cuellar, Jose Barrabes, Imanol Otaegui, Artur Evangelista, Ignacio Ferreira, Vicente Bodi, Jose Rodriguez-Palomares
Summary: This study found that circumferential strain (CS) is the strongest CMR-FT predictor of segmental functional recovery after STEMI. The combination of CS with LGE can improve overall accuracy, especially in segments with 50-74% LGE.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Medicine, General & Internal
Jingxin Wang, Mengxi Yang, Zhi Yang, Lu Ye, Hong Luo, Yingkun Guo
Summary: Myocardial contrast echocardiography (MCE) can effectively predict major adverse cardiac events after acute myocardial infarction (AMI) and provide moderate predictive accuracy. The assessment of myocardial viability (MV) by MCE may become an alternative technique for improving long-term risk stratification in AMI patients.
MEDICINA-LITHUANIA
(2022)
Article
Medicine, General & Internal
Sushil Allen Luis, Chris R. Luis, Mohsen Habibian, Myo T. Lwin, Tahlia C. Gadowski, Jonathan Chan, Christian Hamilton-Craig, Owen Christopher Raffel
Summary: Cardiac magnetic resonance has high diagnostic yield in MINOCA patients and predicts long-term prognosis. MINOCA patients with normal CMR imaging have an increased risk of major adverse cardiac events and lower use of guideline-recommended myocardial infarction therapy compared with those with CMR-confirmed myocardial infarction.
MAYO CLINIC PROCEEDINGS
(2021)
Article
Cardiac & Cardiovascular Systems
Yi Jiang, Yuansong Zhu, Zhenxian Xiang, Bryan Richard Sasmita, Yaxin Wang, Gong Ming, Siyu Chen, Suxin Luo, Bi Huang
Summary: The level of D-dimer upon admission is independently associated with the short-term outcome in patients with cardiogenic shock complicating acute myocardial infarction, and adding D-dimer to traditional risk prediction models improves the accuracy of risk prediction.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Medical Laboratory Technology
Gjin Ndrepepa, Stefan Holdenrieder, Adnan Kastrati
Summary: This study investigated the association between the aspartate aminotransferase to alanine aminotransferase ratio (De Ritis ratio) and the prognosis of patients with acute myocardial infarction (AMI). The results showed that an elevated De Ritis ratio was associated with an increased risk of 3-year mortality in AMI patients.
CLINICA CHIMICA ACTA
(2022)
Article
Cardiac & Cardiovascular Systems
Yan-Xiang Zhou, Yu-Gang Hu, Sheng Cao, Ye Xiong, Jia-Rui Lei, Wen-Yue Yuan, Jin-Ling Chen, Qing Zhou
Summary: This study aims to investigate the prognostic role of qualitative and quantitative myocardial contrast echocardiography (MCE) in patients with acute anterior wall ST-Segment elevation myocardial infarction (STEMI) who underwent successful epicardial recanalization. The results showed that qualitative and quantitative MCE can accurately predict major adverse cardiovascular events (MACEs) in these patients, and their combined predictive value is higher.
INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING
(2022)
Article
Endocrinology & Metabolism
T. Schmitz, D. Freuer, E. Harmel, M. Heier, A. Peters, J. Linseisen, C. Meisinger
Summary: This study investigated the association between stress hyperglycemia ratio (SHR) and admission blood glucose with short- and long-term mortality in diabetic and non-diabetic acute myocardial infarction (AMI) patients. The results showed a nonlinear association between higher admission glucose and SHR with higher 28-day mortality in both diabetic and non-diabetic patients. However, the association with long-term mortality was only significant in diabetic patients. These findings suggest that stress hyperglycemia plays a significant role in short-term prognosis for AMI patients, but less so for long-term prognosis.
ACTA DIABETOLOGICA
(2022)
Article
Cardiac & Cardiovascular Systems
Goro Yoshioka, Atsushi Tanaka, Kensaku Nishihira, Masahiro Natsuaki, Atsushi Kawaguchi, Nozomi Watanabe, Yoshisato Shibata, Koichi Node
Summary: This study investigated the prognostic impact of low serum albumin (LSA) in the remote phase after acute myocardial infarction (AMI) on long-term outcomes. The results showed that LSA after discharge was significantly associated with a higher risk of adverse outcomes, including hospitalization for heart failure and cardiovascular death.
Article
Cardiac & Cardiovascular Systems
Goro Yoshioka, Atsushi Tanaka, Kensaku Nishihira, Masahiro Natsuaki, Atsushi Kawaguchi, Nozomi Watanabe, Yoshisato Shibata, Koichi Node
Summary: This study found that low serum albumin (LSA) in the remote phase after acute myocardial infarction (AMI) is significantly associated with long-term adverse outcomes, regardless of albumin status at admission.
Article
Cardiac & Cardiovascular Systems
Seung Hun Lee, Hyun Kuk Kim, Jong-Hwa Ahn, Min Gyu Kang, Kye-Hwan Kim, Jae Seok Bae, Sang Young Cho, Jin-Sin Koh, Yongwhi Park, Seok Jae Hwang, Diana A. Gorog, Udaya S. Tantry, Kevin P. Bliden, Paul A. Gurbel, Jin-Yong Hwang, Young-Hoon Jeong
Summary: This study evaluated thrombogenicity indices and their prognostic implications in patients undergoing percutaneous coronary intervention (PCI). It found that acute myocardial infarction (AMI) patients had higher platelet-fibrin clot strength and lower fibrinolytic activity compared to non-AMI patients. The combined phenotype of high clot strength and low fibrinolytic activity was associated with post-PCI atherothrombotic events only in AMI patients.
EUROPEAN HEART JOURNAL
(2023)
Review
Cell Biology
Bradley Tucker, Kaivan Vaidya, Blake J. Cochran, Sanjay Patel
Summary: Periprocedural myocardial injury and myocardial infarction are common complications of percutaneous coronary intervention, associated with increased short- and long-term mortality. Inflammation levels before, during, and after the procedure are linked to higher rates of myonecrosis and future cardiovascular events. In addition to inflammation from underlying coronary disease, PCI itself triggers an acute inflammatory response.
Editorial Material
Cardiac & Cardiovascular Systems
David A. Morrow
Summary: This paragraph highlights the complexity and overlapping nature of current diagnostic and prognostic algorithms for high-sensitivity cardiac troponin measurement. It also explains the different zones that indicate varying levels of confidence in diagnosing myocardial injury or myocardial infarction.
EUROPEAN HEART JOURNAL
(2023)
Article
Peripheral Vascular Disease
Yuki Matsuoka, Yohei Sotomi, Shungo Hikoso, Daisaku Nakatani, Katsuki Okada, Tomoharu Dohi, Hirota Kida, Bolrathanak Oeun, Akihiro Sunaga, Taiki Sato, Tetsuhisa Kitamura, Yasuhiko Sakata, Hiroshi Sato, Masatsugu Hori, Issei Komuro, Yasushi Sakata
Summary: This study aimed to investigate the impact of bleeding or thrombotic events during acute phase on subsequent mortality in AMI patients undergoing PCI. The study found that major bleeding within 7 days of PCI was independently associated with higher 30-day and 1-year mortality, whereas ReMI did not affect mortality. This association was only observed in the short term.
JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS
(2023)
Letter
Cardiac & Cardiovascular Systems
Gaetano Nucifora, Carl Gillebert, Joseph B. Selvanayagam
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2016)
Editorial Material
Cardiac & Cardiovascular Systems
Daniele Muser, Michela Puppato, Alessandro Proclemer, Gaetano Nucifora
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2016)
Article
Cardiac & Cardiovascular Systems
Gaetano Nucifora, John-Paul Tantiongco, Gareth Crouch, Jayme Bennetts, Ajay Sinhal, Phillip J. Tully, Craig Bradbrook, Robert A. Baker, Joseph B. Selvanayagam
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2017)
Article
Cardiac & Cardiovascular Systems
Gaetano Nucifora, Giovanni D. Aquaro, Pier Giorgio Masci, Alessandro Pingitore, Massimo Lombardi
AMERICAN JOURNAL OF CARDIOLOGY
(2014)
Article
Cardiac & Cardiovascular Systems
Gaetano Nucifora, Daniele Muser, Giorgio Morocutti, Gianluca Piccoli, Davide Zanuttini, Pasquale Gianfagna, Alessandro Proclemer
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
(2014)
Article
Cardiac & Cardiovascular Systems
Annalisa Sechi, Gaetano Nucifora, Gianluca Piccoli, Andrea Dardis, Bruno Bembi
BMC CARDIOVASCULAR DISORDERS
(2014)
Article
Cardiac & Cardiovascular Systems
Gaetano Nucifora, Daniele Muser, Pier Giorgio Masci, Andrea Barison, Luca Rebellato, Gianluca Piccoli, Elisabetta Daleffe, Mauro Toniolo, Davide Zanuttini, Domenico Facchin, Massimo Lombardi, Alessandro Proclemer
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY
(2014)
Letter
Cardiac & Cardiovascular Systems
Enrico Fabris, Giorgio Morocutti, Gianfranco Sinagra, Alessandro Proclemer, Gaetano Nucifora
CLINICAL RESEARCH IN CARDIOLOGY
(2014)
Editorial Material
Cardiac & Cardiovascular Systems
Daniele Muser, Gaetano Nucifora, Enrico Gianfagna, Daisy Pavoni, Luca Rebellato, Domenico Facchin, Elisabetta Daleffe, Alessandro Proclemer
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2014)
Editorial Material
Medicine, General & Internal
Daniele Muser, Pasquale Santangeli, Gaetano Nucifora
Article
Medicine, General & Internal
Jakub Lagan, Christien Fortune, David Hutchings, Joshua Bradley, Josephine H. Naish, Richard Timoney, Daniel Prescott, Hamish D. C. Bain, Tasneem Bangi, Jerome McIntosh, Robin Egdell, R. Bruce Irwin, David Clark, Erik B. Schelbert, Gaetano Nucifora, Matthias Schmitt, Christopher A. Miller
Summary: This study investigated the utility of contemporary multiparametric CMR in a large prospective cohort of patients with suspected acute myocarditis. The results showed that multiparametric CMR has a high diagnostic yield in suspected acute myocarditis and should be performed early and include parametric mapping. The study also identified clinical characteristics and factors predicting outcome associated with CMR findings.
Article
Medicine, General & Internal
Jakub Lagan, Josephine H. Naish, Christien Fortune, Christopher Campbell, Shien Chow, Manon Pillai, Joshua Bradley, Lenin Francis, David Clark, Anita Macnab, Gaetano Nucifora, Rebecca Dobson, Erik B. Schelbert, Matthias Schmitt, Robert Hawkins, Christopher A. Miller
Summary: High dose interleukin-2 (IL-2) therapy is associated with acute cardiopulmonary inflammation and chronic left ventricular hypertrophy, leading to acute left ventricular dilatation, reduced cardiac function, and prolonged QT interval. Most of these effects are reversible.
Article
Cardiac & Cardiovascular Systems
Charles Carey, Gaetano Nucifora, Anita Macnab
Summary: This article presents a case of recurrent Takotsubo cardiomyopathy, including one episode of the inverted form. The patient had a history of chronic stress and anxiety, and experienced three episodes of Takotsubo cardiomyopathy over a period of four years, one of which was the inverted form. Full cardiac function was restored after each episode, and the patient is now receiving long-term treatment for heart failure and support for her emotional well-being from mental health teams.
EUROPEAN HEART JOURNAL-CASE REPORTS
(2022)
Review
Cardiac & Cardiovascular Systems
Igor Vendramin, Andrea Lechiancole, Daniela Piani, Gaetano Nucifora, Giovanni Benedetti, Sandro Sponga, Daniele Muser, Uberto Bortolotti, Ugolino Livi
Summary: Sutureless and rapid-deployment bioprostheses have been shown to be effective alternatives in complex redo procedures, suitable for replacing degenerated valves, with all patients surviving postoperatively.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2021)
Article
Cardiac & Cardiovascular Systems
Daniele Muser, Chiara Tioni, Ranjit Shah, Joseph B. Selvanayagam, Gaetano Nucifora
AMERICAN JOURNAL OF CARDIOLOGY
(2017)
